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View Structure Prediction Details

Protein: PES4
Organism: Saccharomyces cerevisiae
Length: 611 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PES4.

Description E-value Query
Range
Subject
Range
gi|73974146 - gi|73974146|ref|XP_857039.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...
445.0 [0..82] [505..2]
PABP1_MOUSE - Polyadenylate-binding protein 1 OS=Mus musculus GN=Pabpc1 PE=1 SV=2
445.0 [0..82] [505..2]
PABP1_BOVIN - Polyadenylate-binding protein 1 OS=Bos taurus GN=PABPC1 PE=2 SV=1
gi|109087089 - gi|109087089|ref|XP_001098239.1| PREDICTED: poly(A) binding protein, cytoplasmic 1 isoform 2 [Macaca...
gi|123993665, gi... - gi|168278070|dbj|BAG11013.1| polyadenylate-binding protein 1 [synthetic construct], gi|123999981|gb|...
gi|194036975 - gi|194036975|ref|XP_001927782.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-bind...
PABPC1 - poly(A) binding protein, cytoplasmic 1
gi|73974130, gi|... - gi|73974178|ref|XP_857695.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...
445.0 [0..82] [505..2]
gi|71896197, gi|... - gi|71896197|ref|NP_001026768.1| poly(A) binding protein, cytoplasmic 1 [Gallus gallus], gi|53130422|...
444.0 [0..82] [505..2]

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Predicted Domain #1
Region A:
Residues: [1-76]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYSISNKKPS ILSMVPLNIL KNQDLKVKKD QEKKISFNPV VTPIRPDDYH EKTSRSSSSS  60
   61 HSDSPEFLRI NNNKSG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.806 N/A N/A a.20.1 PGBD-like

Predicted Domain #2
Region A:
Residues: [77-176]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HKNGKLKSFE SKKLVPLFIG DLHETVTEET LKGIFKKYPS FVSAKVCLDS VTKKSLGHGY  60
   61 LNFEDKEEAE KAMEELNYTK VNGKEIRIMP SLRNTTFRKN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 312.927757
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [177-273]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FGTNVFFSNL PLNNPLLTTR VFYDTFSRYG KILSCKLDSR KDIGFVYFED EKTARNVIKM  60
   61 YNNTSFFGKK ILCGIHFDKE VRSVPNFETQ KSRLDAE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.221849
Match: 1fjcA
Description: Nucleolin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [274-377]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TIIEKEQSLN EKHSKGNDKE SKNIYSSSQN SIFIKNLPTI TTRDDILNFF SEVGPIKSIY  60
   61 LSNATKVKYL WAFVTYKNSS DSEKAIKRYN NFYFRGKKLL VTRA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.228787
Match: 1h6kX
Description: CBP20, 20KDa nuclear cap-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [378-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QDKEERAKFI ESQKISTLFL ENLSAVCNKE FLKYLCHQEN IRPFKIQIDG YDENSSTYSG  60
   61 FIKFRNFEDA TRIFNFLNNR LVGGSIVTTS WERQNNAPKY HDGYGMRNIH TSSHPQITPY 120
  121 YQYSHANSLN SPH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 86.056057
Match: 1l3kA
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [511-611]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRDLSSMNSS TRSLIKNKNF NKKVLETFEK QVRRGIDFMR FPSATRDENV HGIAEYIFDT  60
   61 YWNRDVLILD KFLSLLNSSP YHEGVLQKQI EEAASSLGFK R

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.909 N/A N/A c.58.1 Aminoacid dehydrogenase-like, N-terminal domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle