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View Structure Prediction Details

Protein: PES4
Organism: Saccharomyces cerevisiae
Length: 611 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PES4.

Description E-value Query
Range
Subject
Range
gi|73974146 - gi|73974146|ref|XP_857039.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...
445.0 [0..82] [505..2]
PABP1_MOUSE - Polyadenylate-binding protein 1 OS=Mus musculus GN=Pabpc1 PE=1 SV=2
445.0 [0..82] [505..2]
PABP1_BOVIN - Polyadenylate-binding protein 1 OS=Bos taurus GN=PABPC1 PE=2 SV=1
gi|109087089 - gi|109087089|ref|XP_001098239.1| PREDICTED: poly(A) binding protein, cytoplasmic 1 isoform 2 [Macaca...
gi|123993665, gi... - gi|168278070|dbj|BAG11013.1| polyadenylate-binding protein 1 [synthetic construct], gi|123999981|gb|...
gi|194036975 - gi|194036975|ref|XP_001927782.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-bind...
PABPC1 - poly(A) binding protein, cytoplasmic 1
gi|73974130, gi|... - gi|73974178|ref|XP_857695.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...
445.0 [0..82] [505..2]
gi|71896197, gi|... - gi|71896197|ref|NP_001026768.1| poly(A) binding protein, cytoplasmic 1 [Gallus gallus], gi|53130422|...
444.0 [0..82] [505..2]

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Predicted Domain #1
Region A:
Residues: [1-76]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYSISNKKPS ILSMVPLNIL KNQDLKVKKD QEKKISFNPV VTPIRPDDYH EKTSRSSSSS  60
   61 HSDSPEFLRI NNNKSG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.806 N/A N/A a.20.1 PGBD-like
View Download 0.410 N/A N/A a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.410 N/A N/A a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.405 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.387 N/A N/A b.82.3 cAMP-binding domain-like
View Download 0.367 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.351 N/A N/A a.20.1 PGBD-like
View Download 0.320 N/A N/A a.28.1 ACP-like

Predicted Domain #2
Region A:
Residues: [77-176]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HKNGKLKSFE SKKLVPLFIG DLHETVTEET LKGIFKKYPS FVSAKVCLDS VTKKSLGHGY  60
   61 LNFEDKEEAE KAMEELNYTK VNGKEIRIMP SLRNTTFRKN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 312.927757
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [177-273]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FGTNVFFSNL PLNNPLLTTR VFYDTFSRYG KILSCKLDSR KDIGFVYFED EKTARNVIKM  60
   61 YNNTSFFGKK ILCGIHFDKE VRSVPNFETQ KSRLDAE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.221849
Match: 1fjcA
Description: Nucleolin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [274-377]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TIIEKEQSLN EKHSKGNDKE SKNIYSSSQN SIFIKNLPTI TTRDDILNFF SEVGPIKSIY  60
   61 LSNATKVKYL WAFVTYKNSS DSEKAIKRYN NFYFRGKKLL VTRA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.228787
Match: 1h6kX
Description: CBP20, 20KDa nuclear cap-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [378-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QDKEERAKFI ESQKISTLFL ENLSAVCNKE FLKYLCHQEN IRPFKIQIDG YDENSSTYSG  60
   61 FIKFRNFEDA TRIFNFLNNR LVGGSIVTTS WERQNNAPKY HDGYGMRNIH TSSHPQITPY 120
  121 YQYSHANSLN SPH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 86.056057
Match: 1l3kA
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [511-611]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRDLSSMNSS TRSLIKNKNF NKKVLETFEK QVRRGIDFMR FPSATRDENV HGIAEYIFDT  60
   61 YWNRDVLILD KFLSLLNSSP YHEGVLQKQI EEAASSLGFK R

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.909 N/A N/A c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.907 N/A N/A a.118.1 ARM repeat
View Download 0.907 N/A N/A a.118.1 ARM repeat
View Download 0.844 N/A N/A c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.829 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.813 N/A N/A a.118.1 ARM repeat
View Download 0.813 N/A N/A a.118.1 ARM repeat
View Download 0.808 N/A N/A c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.773 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.764 N/A N/A a.118.1 ARM repeat


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle