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View Structure Prediction Details

Protein: ATG18
Organism: Saccharomyces cerevisiae
Length: 500 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATG18.

Description E-value Query
Range
Subject
Range
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [2..499] [903..1413]
gi|17225210 - gi|17225210|gb|AAL37301.1|AF323585_1 beta transducin-like protein HET-D2Y [Podospora anserina]
0.0 [1..499] [827..1296]

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Predicted Domain #1
Region A:
Residues: [1-79]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDSSPTINF INFNQTGTCI SLGTSKGFKI FNCEPFGKFY SEDSGGYAIV EMLFSTSLLA  60
   61 LVGIGDQPAL SPRRLRIIN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.913 0.006 protein targeting to vacuole b.1.14 Invasin/intimin cell-adhesion fragments

Predicted Domain #2
Region A:
Residues: [80-131]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKKHSIICEV TFPTSILSVK MNKSRLVVLL QEQIYIYDIN TMRLLHTIET NP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.69897
Match: 1gg2B_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.8484919978091 bayes_pls_golite062009
protein binding 1.42618832381942 bayes_pls_golite062009
transporter activity 1.21549336905926 bayes_pls_golite062009
nucleic acid binding 0.624115832843391 bayes_pls_golite062009
substrate-specific transporter activity 0.479978536094414 bayes_pls_golite062009
hydrolase activity 0.36638536879917 bayes_pls_golite062009
cytoskeletal protein binding 0.359536347486199 bayes_pls_golite062009
signal transducer activity 0.343972561304413 bayes_pls_golite062009
molecular transducer activity 0.343972561304413 bayes_pls_golite062009
transcription regulator activity 0.282387003961579 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [132-500]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPRGLMAMSP SVANSYLVYP SPPKVINSEI KAHATTNNIT LSVGGNTETS FKRDQQDAGH  60
   61 SDISDLDQYS SFTKRDDADP TSSNGGNSSI IKNGDVIVFN LETLQPTMVI EAHKGEIAAM 120
  121 AISFDGTLMA TASDKGTIIR VFDIETGDKI YQFRRGTYAT RIYSISFSED SQYLAVTGSS 180
  181 KTVHIFKLGH SMSNNKLDSD DSNMEEAAAD DSSLDTTSID ALSDEENPTR LAREPYVDAS 240
  241 RKTMGRMIRY SSQKLSRRAA RTLGQIFPIK VTSLLESSRH FASLKLPVET NSHVMTISSI 300
  301 GSPIDIDTSE YPELFETGNS ASTESYHEPV MKMVPIRVVS SDGYLYNFVM DPERGGDCLI 360
  361 LSQYSILMD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.69897
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle