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View Structure Prediction Details

Protein: DAK2
Organism: Saccharomyces cerevisiae
Length: 591 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DAK2.

Description E-value Query
Range		 Subject
Range
DAK2 - Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress a...
DAK2_YEAST - Dihydroxyacetone kinase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DAK2 PE=3 SV=1
 0.0 [1..591] [1..591]
DAK_PICAN - Dihydroxyacetone kinase OS=Pichia angusta GN=DAK PE=3 SV=1
DAK_PICAN - Dihydroxyacetone kinase OS=Pichia angusta GN=DAK PE=3 SV=1
 0.0 [1..589] [1..602]
dak2 - dihydroxyacetone kinase Dak2
DAK2_SCHPO - Dihydroxyacetone kinase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dak2 PE=3 SV=2
 0.0 [1..588] [1..588]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [1..588] [1..588]
dak2 - dihydroxyacetone kinase Dak2
DAK2_SCHPO - Dihydroxyacetone kinase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dak2 PE=3 SV=2
 0.0 [1..588] [1..588]
gi|238032869, gi... - gi|254571923|ref|XP_002493071.1| Dihydroxyacetone kinase, required for detoxification of dihydroxyac...
DAK_PICPA - Dihydroxyacetone kinase OS=Komagataella pastoris GN=DAK PE=3 SV=1
jgi|Picpa1|39132... - null
 0.0 [1..589] [1..601]
gi|15229519, gi|... - gi|71143068|gb|AAZ23925.1| At3g17770 [Arabidopsis thaliana], gi|15229519|ref|NP_188404.1| dihydroxya...
 0.0 [3..576] [6..574]
gi|18309082, gi|... - gi|18309082|ref|NP_561016.1| dihydroxyacetone kinase [Clostridium perfringens str. 13], gi|18143757|...
 0.0 [2..582] [1..574]

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Predicted Domain #1
Region A:
Residues: [1-591] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHKQFKSDG NIVTPYLLGL ARSNPGLTVI KHDRVVFRTA SAPNSGNPPK VSLVSGGGSG  60
   61 HEPTHAGFVG EGALDAIAAG AIFASPSTKQ IYSAIKAVES PKGTLIIVKN YTGDIIHFGL 120
  121 AAERAKAAGM KVELVAVGDD VSVGKKKGSL VGRRGLGATV LVHKIAGAAA SHGLELAEVA 180
  181 EVAQSVVDNS VTIAASLDHC TVPGHKPEAI LGENEYEIGM GIHNESGTYK SSPLPSISEL 240
  241 VSQMLPLLLD EDEDRSYVKF EPKEDVVLMV NNMGGMSNLE LGYAAEVISE QLIDKYQIVP 300
  301 KRTITGAFIT ALNGPGFGIT LMNASKAGGD ILKYFDYPTT ASGWNQMYHS AKDWEVLAKG 360
  361 QVPTAPSLKT LRNEKGSGVK ADYDTFAKIL LAGIAKINEV EPKVTWYDTI AGDGDCGTTL 420
  421 VSGGEALEEA IKNHTLRLED AALGIEDIAY MVEDSMGGTS GGLYSIYLSA LAQGVRDSGD 480
  481 KELTAETFKK ASNVALDALY KYTRARPGYR TLIDALQPFV EALKAGKGPR AAAQAAYDGA 540
  541 EKTRKMDALV GRASYVAKEE LRKLDSEGGL PDPGAVGLAA LLDGFVTAAG Y

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.85
Match: 1e1cB
Description: Methylmalonyl-CoA mutase beta subunit, domain 1; Methylmalonyl-CoA mutase beta subunit, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glycerone kinase activity 3.66907507772019 bayes_pls_golite062009
binding 0.69038000262198 bayes_pls_golite062009
catalytic activity 0.142389024724964 bayes_pls_golite062009
protein binding 0.133716715271428 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle