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View Structure Prediction Details

Protein: GAT1
Organism: Saccharomyces cerevisiae
Length: 510 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GAT1.

Description E-value Query
Range
Subject
Range
TCNA_TRYCR - Sialidase OS=Trypanosoma cruzi GN=TCNA PE=2 SV=1
225.0 [0..11] [498..603]
gi|70869911 - gi|70869911|gb|EAN84377.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71407532 - gi|71407532|ref|XP_806228.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
208.0 [0..24] [498..669]
gi|4808166 - gi|4808166|emb|CAB42797.1| largest subunit of the RNA polymerase II complex [Drosophila pseudoobscur...
185.0 [0..70] [434..1419]
RpII215-PA - The gene RNA polymerase II 215kD subunit is referred to in FlyBase by the symbol Dmel\RpII215 (CG155...
178.0 [0..70] [434..1497]
gi|61372534, gi|... - gi|61372538|gb|AAX43862.1| GATA binding protein 3 [synthetic construct], gi|61372534|gb|AAX43861.1| ...
174.0 [0..17] [441..32]
GATA3 - GATA binding protein 3
174.0 [0..17] [441..32]
gi|9695347 - gi|9695347|gb|AAF97432.1|U23947_9 VsaC1 [Mycoplasma pulmonis]
173.0 [0..34] [496..47]
gi|15828996 - gi|15828996|ref|NP_326356.1| lipoprotein VSAC (fragment) [Mycoplasma pulmonis UAB CTIP]
gi|14089939, gi|... - pir||E90577 lipoprotein vsaC [imported] - Mycoplasma pulmonis (strain UAB CTIP) (fragment), gi|14089...
171.0 [0..46] [496..39]

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Predicted Domain #1
Region A:
Residues: [1-238]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHVFFPLLFR PSPVLFIACA YIYIDIYIHC TRCTVVNITM STNRVPNLDP DLNLNKEIWD  60
   61 LYSSAQKILP DSNRILNLSW RLHNRTSFHR INRIMQHSNS IMDFSASPFA SGVNAAGPGN 120
  121 NDLDDTDTDN QQFFLSDMNL NGSSVFENVF DDDDDDDDVE THSIVHSDLL NDMDSASQRA 180
  181 SHNASGFPNF LDTSCSSSFD DHFIFTNNLP FLNNNSINNN HSHNSSHNNN SPSIANNT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [239-296]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NANTNTNTSA STNTNSPLLR RNPSPSIVKP GSRRNSSVRK KKPALKKIKS STSVQSSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 91.9897
Match: 1gnfA
Description: SOLUTION STRUCTURE OF THE N-TERMINAL ZINC FINGER OF MURINE GATA-1, NMR, 25 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [297-404]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPPSNTSSNP DIKCSNCTTS TTPLWRKDPK GLPLCNACGL FLKLHGVTRP LSLKTDIIKK  60
   61 RQRSSTKINN NITPPPSSSL NPGAAGKKKN YTASVAASKR KNSLNIVA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 192.69897
Match: 4gatA
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [405-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLKSQDIPIP KIASPSIPQY LRSNTRHHLS SSVPIEAETF SSFRPDMNMT MNMNLHNAST  60
   61 SSFNNEAFWK PLDSAIDHHS GDTNPNSNMN TTPNGNLSLD WLNLNL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle