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View Structure Prediction Details

Protein: GAT1
Organism: Saccharomyces cerevisiae
Length: 510 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GAT1.

Description E-value Query
Range
Subject
Range
TCNA_TRYCR - Sialidase OS=Trypanosoma cruzi GN=TCNA PE=2 SV=1
225.0 [0..11] [498..603]
gi|70869911 - gi|70869911|gb|EAN84377.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71407532 - gi|71407532|ref|XP_806228.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
208.0 [0..24] [498..669]
gi|4808166 - gi|4808166|emb|CAB42797.1| largest subunit of the RNA polymerase II complex [Drosophila pseudoobscur...
185.0 [0..70] [434..1419]
RpII215-PA - The gene RNA polymerase II 215kD subunit is referred to in FlyBase by the symbol Dmel\RpII215 (CG155...
178.0 [0..70] [434..1497]
gi|61372534, gi|... - gi|61372538|gb|AAX43862.1| GATA binding protein 3 [synthetic construct], gi|61372534|gb|AAX43861.1| ...
174.0 [0..17] [441..32]
GATA3 - GATA binding protein 3
174.0 [0..17] [441..32]
gi|9695347 - gi|9695347|gb|AAF97432.1|U23947_9 VsaC1 [Mycoplasma pulmonis]
173.0 [0..34] [496..47]
gi|15828996 - gi|15828996|ref|NP_326356.1| lipoprotein VSAC (fragment) [Mycoplasma pulmonis UAB CTIP]
gi|14089939, gi|... - pir||E90577 lipoprotein vsaC [imported] - Mycoplasma pulmonis (strain UAB CTIP) (fragment), gi|14089...
171.0 [0..46] [496..39]

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Predicted Domain #1
Region A:
Residues: [1-238]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHVFFPLLFR PSPVLFIACA YIYIDIYIHC TRCTVVNITM STNRVPNLDP DLNLNKEIWD  60
   61 LYSSAQKILP DSNRILNLSW RLHNRTSFHR INRIMQHSNS IMDFSASPFA SGVNAAGPGN 120
  121 NDLDDTDTDN QQFFLSDMNL NGSSVFENVF DDDDDDDDVE THSIVHSDLL NDMDSASQRA 180
  181 SHNASGFPNF LDTSCSSSFD DHFIFTNNLP FLNNNSINNN HSHNSSHNNN SPSIANNT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [239-296]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NANTNTNTSA STNTNSPLLR RNPSPSIVKP GSRRNSSVRK KKPALKKIKS STSVQSSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 91.9897
Match: 1gnfA
Description: SOLUTION STRUCTURE OF THE N-TERMINAL ZINC FINGER OF MURINE GATA-1, NMR, 25 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [297-404]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPPSNTSSNP DIKCSNCTTS TTPLWRKDPK GLPLCNACGL FLKLHGVTRP LSLKTDIIKK  60
   61 RQRSSTKINN NITPPPSSSL NPGAAGKKKN YTASVAASKR KNSLNIVA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 192.69897
Match: 4gatA
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [405-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLKSQDIPIP KIASPSIPQY LRSNTRHHLS SSVPIEAETF SSFRPDMNMT MNMNLHNAST  60
   61 SSFNNEAFWK PLDSAIDHHS GDTNPNSNMN TTPNGNLSLD WLNLNL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.796 N/A N/A a.133.1 Phospholipase A2, PLA2
View Download 0.796 N/A N/A a.133.1 Phospholipase A2, PLA2
View Download 0.749 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.749 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.509 N/A N/A a.4.12 TrpR-like
View Download 0.509 N/A N/A a.4.12 TrpR-like
View Download 0.500 N/A N/A b.36.1 PDZ domain-like
View Download 0.362 N/A N/A a.118.14 FliG
View Download 0.362 N/A N/A a.118.14 FliG
View Download 0.359 N/A N/A a.29.4 RecG, N-terminal domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle