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View Structure Prediction Details

Protein: GLC7
Organism: Saccharomyces cerevisiae
Length: 312 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLC7.

Description E-value Query
Range		 Subject
Range
PP1A_MOUSE - Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Mus musculus GN=Ppp1ca PE=1 SV=1
tr|G3MX90|G3MX90... - Serine/threonine-protein phosphatase OS=Bos taurus PE=3 SV=1
gi|54035381 - gb|AAH84049.1| Unknown (protein for MGC:98412) [Xenopus laevis]
 0.0 [2..301] [3..302]
gi|1535 - gi|1535|emb|CAA30645.1| unnamed protein product [Oryctolagus cuniculus]
 0.0 [2..301] [3..302]
gi|999339 - gi|999339|gb|AAB34333.1| protein phosphatase 1 alpha; PP1 alpha [Rattus sp.]
PP1A_RABIT - Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Oryctolagus cuniculus GN=PPP1CA ...
PPP1CA - protein phosphatase 1, catalytic subunit, alpha isozyme
ENSMMUG000000172... - null, null
PP1A_BOVIN - Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Bos taurus GN=PPP1CA PE=2 SV=1
IPI:IPI00323370.... - Ensembl_locations(Chr-bp):None Serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit
PP1A_RAT - Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Rattus norvegicus GN=Ppp1ca PE=1...
gi|60656413 - gi|60656413|gb|AAX32770.1| protein phosphatase 1 catalytic subunit alpha isoform [synthetic construc...
HGNC:9281|MIM:17... - phosphatase 1, catalytic subunit, alpha isozyme
gi|87621715, gi|... - gi|87621715|gb|ABD38708.1| protein phosphatase 1 catalytic subunit alpha isoform [Sus scrofa], gi|11...
 0.0 [2..301] [3..302]
GLC7 - Type 1 serine/threonine protein phosphatase catalytic subunit, involved in many processes (eg: glyco...
gi|151944848 - gi|151944848|gb|EDN63107.1| protein phosphatase type I [Saccharomyces cerevisiae YJM789]
PP12_YEAST - Serine/threonine-protein phosphatase PP1-2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) ...
Sbay_5.254 - null
gi|190405694 - gi|190405694|gb|EDV08961.1| protein phosphatase type I [Saccharomyces cerevisiae RM11-1a]
 0.0 [1..312] [1..312]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [2..301] [3..302]
PP1G_RAT - Serine/threonine-protein phosphatase PP1-gamma catalytic subunit OS=Rattus norvegicus GN=Ppp1cc PE=1...
gi|55250791 - gb|AAH86013.1| Unknown (protein for MGC:98061) [Xenopus laevis]
PP1G_BOVIN - Serine/threonine-protein phosphatase PP1-gamma catalytic subunit OS=Bos taurus GN=PPP1CC PE=2 SV=1
PP1G_MOUSE - Serine/threonine-protein phosphatase PP1-gamma catalytic subunit OS=Mus musculus GN=Ppp1cc PE=1 SV=1
gi|87621736, gi|... - gi|87621736|gb|ABD38709.1| protein phosphatase 1 catalytic subunit gamma isoform [Sus scrofa], gi|11...
 0.0 [2..301] [3..302]
gi|5917726 - gi|5917726|gb|AAD56010.1|AF178530_1 serine/threonine protein phosphatase 1; PP1 [Malus x domestica]
 0.0 [4..303] [10..309]
PP11_ACEPE - Serine/threonine-protein phosphatase PP1 isozyme 1 OS=Acetabularia peniculus PE=3 SV=1
 0.0 [1..303] [1..301]

Back

Predicted Domain #1
Region A:
Residues: [1-312] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSQPVDVDN IIDRLLEVRG SKPGQQVDLE ENEIRYLCSK ARSIFIKQPI LLELEAPIKI  60
   61 CGDIHGQYYD LLRLFEYGGF PPESNYLFLG DYVDRGKQSL ETICLLLAYK IKYPENFFIL 120
  121 RGNHECASIN RIYGFYDECK RRYNIKLWKT FTDCFNCLPI AAIIDEKIFC MHGGLSPDLN 180
  181 SMEQIRRVMR PTDIPDVGLL CDLLWSDPDK DIVGWSENDR GVSFTFGPDV VNRFLQKQDM 240
  241 ELICRAHQVV EDGYEFFSKR QLVTLFSAPN YCGEFDNAGA MMSVDESLLC SFQILKPAQK 300
  301 SLPRQAGGRK KK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1734.0
Match: 1it6A_
Description: Protein phosphatase-1 (PP-1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphoprotein phosphatase activity 11.6417995308386 bayes_pls_golite062009
protein serine/threonine phosphatase activity 10.6440947462013 bayes_pls_golite062009
phosphatase activity 10.5525832502704 bayes_pls_golite062009
phosphoric ester hydrolase activity 10.3702645338723 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 9.02791306892273 bayes_pls_golite062009
calcium-dependent protein serine/threonine phosphatase activity 6.04386346716682 bayes_pls_golite062009
myosin phosphatase activity 5.31703100176823 bayes_pls_golite062009
hydrolase activity 3.13006743434485 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.68552051869632 bayes_pls_golite062009
kinase activity 1.67788383575784 bayes_pls_golite062009
structural molecule activity 1.5850868178597 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.57807175808088 bayes_pls_golite062009
protein kinase activity 1.4514460578232 bayes_pls_golite062009
binding 1.44538582463569 bayes_pls_golite062009
catalytic activity 1.39852585255405 bayes_pls_golite062009
transferase activity 1.3407391509244 bayes_pls_golite062009
protein binding 1.33435965029646 bayes_pls_golite062009
transporter activity 1.24767072239634 bayes_pls_golite062009
molecular transducer activity 1.08090214431427 bayes_pls_golite062009
signal transducer activity 1.08090214431427 bayes_pls_golite062009
calmodulin binding 0.77173071932406 bayes_pls_golite062009
protein serine/threonine kinase activity 0.66803085638835 bayes_pls_golite062009
substrate-specific transporter activity 0.528189469950839 bayes_pls_golite062009
structural constituent of muscle 0.126411744957937 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle