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View Structure Prediction Details

Protein: SAK1
Organism: Saccharomyces cerevisiae
Length: 1142 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SAK1.

Description E-value Query
Range
Subject
Range
SAK1_YEAST - SNF1-activating kinase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SAK1 PE=1 SV=1
SAK1 - Upstream serine/threonine kinase for the SNF1 complex; partially redundant with Elm1p and Tos3p; mem...
0.0 [1..1142] [1..1142]
CDPKL_ARATH - Calcium-dependent protein kinase 21 OS=Arabidopsis thaliana GN=CPK21 PE=1 SV=1
0.0 [61..637] [5..525]
gi|16215467 - gi|16215467|emb|CAC82998.1| calcium-dependent protein kinase 2 [Nicotiana tabacum]
0.0 [16..646] [8..571]
gi|16215475 - gi|16215475|emb|CAC83000.1| calcium-dependent protein kinase 2 [Nicotiana benthamiana]
0.0 [16..646] [8..571]
gi|15289758 - gi|15289758|dbj|BAB63463.1| calcium dependent protein kinase [Solanum tuberosum]
0.0 [16..646] [8..568]
CDPK2_ORYSJ - Calcium-dependent protein kinase isoform 2 OS=Oryza sativa subsp. japonica GN=CPK2 PE=2 SV=2
CDPK2_ORYSA - Calcium-dependent protein kinase, isoform 2 (EC 2.7.11.1) (CDPK 2) - Oryza sativa (Rice)
0.0 [27..634] [2..527]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRSDKKVNV EEVNVPSNLQ IELEKSGTSS SVSLRSPTKS SATNLAGMAE GARDNASIAS  60
   61 SSVDSLNMLL ERQRVRQLNH PQHQQHISSS LAKTPT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [97-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTSSFCSSGS SKNKVKETNR ISLTYDPVSK RKVLNTYEII KELGHGQHGK VKLARDILSK  60
   61 QLVAIKIVDR HEKKQRKFFT FIKSSKISEN DKIKREIAIM KKCHHKHVVQ LIEVLDDLKS 120
  121 RKIYLVLEYC SR

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [473-496]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FQCNQTDQFE PISISKHELK NAVS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 350.70927
Match: 1a06__
Description: Calmodulin-dependent protein kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [229-472]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEVKWCPPDC MESDAKGPSL LSFQETREIL RGVVLGLEYL HYQGIIHRDI KPANLLISGD  60
   61 GTVKISDFGV SLAASSTNSS DSSESLDELE LAKTVGTPAF FAPEMCLGED AFTRYNLTKE 120
  121 NLFRGSCISF MIDIWAVGVT LYCLLFGMLP FFSDFELKLF EKIVNDPLKF PTFKEIQSNK 180
  181 VSKVSCEEEY EMAKDLLLKL LEKNPQKRMT IPAIKKHPFV SWDFDHVPEN DEKLLSSVLE 240
  241 QKLR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 350.70927
Match: 1a06__
Description: Calmodulin-dependent protein kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [497-569]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVGKKIKESV LKSIPLKDPS DLSNKNYLHP TETTRGRGDA NVIVSEGSVL SNIKELSAND  60
   61 GCLNTDSDTN INI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.0
Match: 1iq5A_
Description: Calmodulin
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [570-644]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDDDHYSGDD NDGHLTKREL ERELNKFDDK HEAGNMVNLP INSSFASLDS FYIDNFAMAR  60
   61 MGMSSPEAGD SVSSV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.0
Match: 1iq5A_
Description: Calmodulin
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [645-796]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNLPSAPSST RLGRSPVFSG VTNQPSPIRP VLPQQKSSFC ATGRYDKSHN SLLRNSSSHL  60
   61 TSYNSGRPSS RTGRMNSRNQ NLPKIPNSLS KISTTKLTEL RVPKDSEIPS PAKNPNADRL 120
  121 RRFPVKKNTK TPAIKDPPRI NINSSDKSGS KN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.78
Match: 1jl5A
Description: Leucine rich effector protein YopM
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [797-1142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPIKSLYQRM KQSKDNSKTF EVRRGNFFSH FNGDDDDSSS QSSVTSSGSE SDSELSSTSS  60
   61 SCTSGTQSRN SSNNNAYSET ESLPFEFGVD SEDGSGVLLR DLPNEDQIRP FLDIQPCRRM 120
  121 KVKSSLNLEP PSVSSSSSSS SDEDELILNV GTAGHRRRHN SSKLSELSNS PQKGSNNFMY 180
  181 SNGSVHDSET TITPQNMDDL TLHQALSRSQ PISKPGPLVL PKRLDQKKAT TETSNLTDIV 240
  241 EFNGNNDHRK DKNFDKVLYS RDLLKDALSS TNAGRRRSIP SNKIRGRKDA SITMSTNVGN 300
  301 DEHARNTSCH GDKGQENGAI KQRTHERSRS LTVAELNEEK RRSALP

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.78
Match: 1jl5A
Description: Leucine rich effector protein YopM
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle