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View Structure Prediction Details

Protein: YAT2
Organism: Saccharomyces cerevisiae
Length: 923 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YAT2.

Description E-value Query
Range
Subject
Range
YAT2_YEAST - Carnitine O-acetyltransferase YAT2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YAT2 ...
YAT2 - Carnitine acetyltransferase; has similarity to Yat1p, which is a carnitine acetyltransferase associa...
0.0 [1..923] [1..923]
gi|2511761 - gi|2511761|gb|AAC82487.1| carnitine acetyl transferase FacC [Emericella nidulans]
0.0 [8..788] [27..741]
CHAT - choline O-acetyltransferase
0.0 [6..753] [115..739]
gi|18958223, gi|... - gi|57164287|ref|NP_001009259.1| carnitine palmitoyltransferase 1B [Ovis aries], gi|18958223|emb|CAC8...
0.0 [6..742] [155..770]
gi|19309413, gi|... - gi|41581312|emb|CAE47961.1| carnitine acetyl transferase, putative [Aspergillus fumigatus], gi|19309...
0.0 [9..798] [31..769]
CPT1B_MOUSE - Carnitine O-palmitoyltransferase 1, muscle isoform OS=Mus musculus GN=Cpt1b PE=1 SV=1
0.0 [6..743] [156..772]

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Predicted Domain #1
Region A:
Residues: [1-780]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSGSTIVSS DKSGRTFKHE EELPKLPLPK LCDTLQRLKE SLEPLYYADG YYQHPLDPEQ  60
   61 IEKLSSIIRD FEENPVSEKL QSKLQSYHDT RDCYLDELHL DINNQTSTRE IQDDVLPRNP 120
  121 FLVLADDALP NITQADRSAV LVHSAARFIS ALKQDLLPPD INATNGKPLS MAPFLNLFGT 180
  181 TRSPVFQRGE VENFDLNKPY TASDLEDPDY SSDEDDNDEP TQKDFDDRKR KHEEDIFTGN 240
  241 GITIKRHPDS KHILIISRGQ YYTLEVLDST NKIIYTAAEL TTIFNHIIKD SSGIEKSTAL 300
  301 GSLTSHSFRN WKYARKRLQK RYPNELHRID SALFVLVLDE SQEETTNDGD DTADISQMFN 360
  361 RTITERDKKC TSANCKRVFY GTSIINSKGH QVGSCVSRWY DKLQLVVTAD AKATVIWDSF 420
  421 TCDGSVVLRF TSEIYTESVL RLARDVNAGD PQFSLWPNVT QMDPETKKLM TATISADGGG 480
  481 PSEIDPKLVV NKIDWSFSNI LNTHVHLSET KLADLISKYD IVRASIPLGR RSAQRLGVKP 540
  541 DSMVQVALQI AHYALYGRMV FGLEPVSTRG FKNSRSSFIN IQSQALLELC QLFISSSIDG 600
  601 TDKLDKFIQT CETHNNMVKH AKSGVGYEKH FNALKYLFKF HDHFGIHLSG DESSAAKDLF 660
  661 ENPLVLPFSQ PELIVANCGN AATTTFGITP AVPHGFGIGY IIKDDQVDLT VTSQFRQGDR 720
  721 LMFMLSWVLG EIRSYWRMSR GTSHNKTGVK ISPVVDKLYE MDNAVNNPPK RNGHTVNGSR 780
  781 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 245.455932
Match: PF00755
Description: Choline/Carnitine o-acyltransferase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
carnitine O-acyltransferase activity 7.54616819269984 bayes_pls_golite062009
carnitine O-acetyltransferase activity 7.38318207912192 bayes_pls_golite062009
choline O-acetyltransferase activity 6.09272417016149 bayes_pls_golite062009
octanoyltransferase activity 4.52268776339565 bayes_pls_golite062009
O-octanoyltransferase activity 4.52268776339565 bayes_pls_golite062009
carnitine O-octanoyltransferase activity 4.52268776339565 bayes_pls_golite062009
carnitine O-palmitoyltransferase activity 3.83467723502092 bayes_pls_golite062009
O-palmitoyltransferase activity 3.83467723502092 bayes_pls_golite062009
transferase activity, transferring acyl groups 3.7327637835604 bayes_pls_golite062009
O-acyltransferase activity 3.7101056995294 bayes_pls_golite062009
acyltransferase activity 3.08588280042054 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.027770031317 bayes_pls_golite062009
S-acyltransferase activity 2.74258684113582 bayes_pls_golite062009
O-acetyltransferase activity 2.37098434941789 bayes_pls_golite062009
dihydrolipoamide S-acyltransferase activity 2.20915191604487 bayes_pls_golite062009
dihydrolipoyllysine-residue acetyltransferase activity 2.0783127648124 bayes_pls_golite062009
S-acetyltransferase activity 2.04797137596259 bayes_pls_golite062009
transferase activity 1.78692523095641 bayes_pls_golite062009
choline binding 1.59193088660278 bayes_pls_golite062009
catalytic activity 1.51562638409295 bayes_pls_golite062009
succinyltransferase activity 1.48650517081097 bayes_pls_golite062009
acetyltransferase activity 1.12787027896966 bayes_pls_golite062009
S-succinyltransferase activity 1.03771162623809 bayes_pls_golite062009
dihydrolipoyllysine-residue succinyltransferase activity 1.03771162623809 bayes_pls_golite062009
binding 0.999555841397607 bayes_pls_golite062009
palmitoyltransferase activity 0.607756896737891 bayes_pls_golite062009
protein binding 0.104367069798378 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [781-923]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTSSSSQVNL NRYGGFFDLE GHIDSRNISK TPSMKNLQKT FNGLTMSADN DHSSSAVSVP  60
   61 TEKEKLNTGH EILQIQPREV ASNGLEADDE TDIEIVAGNA DGTSSSASSA TSLNSKKRNV 120
  121 INSRFDIDFD RSRVGRKVAT LDQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle