YRC Public Data Repository - Protein Structure Prediction

Protein:	HSP31
Organism:	Saccharomyces cerevisiae
Length:	237 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HSP31.

Description	E-value	Query Range	Subject Range
HSP31 - Possible chaperone and cysteine protease with similarity to E. coli Hsp31; member of the DJ-1/ThiJ/P... HSP31_YEAST - Glutathione-independent glyoxalase HSP31 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN...	2.0E-52	[1..237]	[1..237]
HSP31_SCHPO - Glutathione-independent glyoxalase hsp3101 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN... SPCC757.03c - ThiJ domain protein	7.0E-49	[1..233]	[1..236]
gi\|25309714 - pir\|\|E95867 conserved hypothetical protein [imported] - Sinorhizobium meliloti (strain 1021) magapla... gi\|16263953, gi\|... - gi\|16263953\|ref\|NP_436745.1\| hypothetical protein SM_b20212 [Sinorhizobium meliloti 1021], gi\|151400...	8.0E-46	[1..236]	[1..226]
gi\|119187515, gi... - gi\|90303150\|gb\|EAS32781.1\| hypothetical protein CIMG_03805 [Coccidioides immitis RS], gi\|119187515\|r... gi\|12007496 - gi\|12007496\|gb\|AAG45226.1\|AF326276_1 macrophage binding protein [Coccidioides immitis] gi\|240108165 - gi\|240108165\|gb\|EER26339.1\| DJ-1/PfpI family protein [Coccidioides posadasii C735 delta SOWgp]	9.0E-46	[3..233]	[5..235]

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Predicted Domain #1

Region A:
Residues: [1-237]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPKKVLLAL TSYNDVFYSD GAKTGVFVVE ALHPFNTFRK EGFEVDFVSE TGKFGWDEHS  60
   61 LAKDFLNGQD ETDFKNKDSD FNKTLAKIKT PKEVNADDYQ IFFASAGHGT LFDYPKAKDL 120
  121 QDIASEIYAN GGVVAAVCHG PAIFDGLTDK KTGRPLIEGK SITGFTDVGE TILGVDSILK 180
  181 AKNLATVEDV AKKYGAKYLA PVGPWDDYSI TDGRLVTGVN PASAHSTAVR SIDALKN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.69897
Match:	1g2iA_
Description:	Intracellular protease
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.761311388604334	bayes_pls_golite062009
binding	0.674707430307546	bayes_pls_golite062009
ligase activity	0.314215307503825	bayes_pls_golite062009
hydrolase activity	0.132707384514464	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: