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View Structure Prediction Details

Protein: YDR532C
Organism: Saccharomyces cerevisiae
Length: 385 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDR532C.

Description E-value Query
Range
Subject
Range
YDR532C - Subunit of a kinetochore-microtubule binding complex with Spc105p that bridges centromeric heterochr...
KRE28_YEAST - Spindle pole body component KRE28 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KRE28 ...
0.0 [1..385] [1..385]
gi|13259497 - gi|13259497|ref|NP_002883.2| retinoblastoma-binding protein 1 isoform I [Homo sapiens]
2.0E-88 [16..276] [700..946]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
8.0E-84 [16..276] [363..609]

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Predicted Domain #1
Region A:
Residues: [1-131]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTGSASIKD YETVLTDIED SIAVSSEEVL NNQELRLKNT LHEITSSILA INEENKFVNP  60
   61 LRNDESLDVE GKEVFVNPKI LSAKIKEFNK LMELLKLTYL EQETLDYFFR FTLSSTKPLQ 120
  121 LDSEKDPQFV K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.820 0.196 spindle pole body a.45.1 Glutathione S-transferase (GST), C-terminal domain

Predicted Domain #2
Region A:
Residues: [132-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNERVNDLKE EISNVQESKI EQIKAEIQET GHNFAERQDL INELYLEATG DIENCWDSLN  60
   61 ELKNLTNKED KNMMGEKDTI LNSSDSDDFV EETYTNWQKL LFLQKQNQRL TKELKEMHEV 120
  121 KNQIIRKGEQ SKKEDSGHLM ANESEL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [324-385]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IAISLSDLKR PMIKDITILQ KAGGNIVTDI EASSKFNNKY RNNTKVQIFE VMDDIISELT  60
   61 NE

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.44
Match: 1qoyA
Description: Hemolysin E (HlyE, ClyA, SheA)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [278-323]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CQSINLLTKF WEKHFLLKGS KTTILNFEIF TQLGKVQFEI KDMQYI

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.44
Match: 1qoyA
Description: Hemolysin E (HlyE, ClyA, SheA)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle