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View Structure Prediction Details

Protein: LPP1
Organism: Saccharomyces cerevisiae
Length: 274 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LPP1.

Description E-value Query
Range
Subject
Range
gi|27542785 - gi|27542785|gb|AAO16875.1| PAP2A-GFP fusion protein [synthetic construct]
249.0 [0..5] [268..1]
PLPP1_CAVPO - Phospholipid phosphatase 1 OS=Cavia porcellus GN=PLPP1 PE=2 SV=1
236.0 [0..5] [269..1]
gi|122692411, gi... - gi|81674095|gb|AAI09902.1| Phosphatidic acid phosphatase type 2A [Bos taurus], gi|122692411|ref|NP_0...
236.0 [0..5] [269..1]
gi|3015569 - gi|3015569|gb|AAC32041.1| type-2 phosphatidic acid phosphohydrolase [Homo sapiens]
233.0 [0..5] [268..1]
PLPP1_MOUSE - Phospholipid phosphatase 1 OS=Mus musculus GN=Plpp1 PE=1 SV=1
229.0 [0..5] [268..1]

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Predicted Domain #1
Region A:
Residues: [1-64]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISVMADEKH KEYFKLYYFQ YMIIGLCTIL FLYSEISLVP RGQNIEFSLD DPSISKRYVP  60
   61 NELV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [65-274]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPLECLILSV GLSNMVVFWT CMFDKDLLKK NRVKRLRERP DGISNDFHFM HTSILCLMLI  60
   61 ISINAALTGA LKLIIGNLRP DFVDRCIPDL QKMSDSDSLV FGLDICKQTN KWILYEGLKS 120
  121 TPSGHSSFIV STMGFTYLWQ RVFTTRNTRS CIWCPLLALV VMVSRVIDHR HHWYDVVSGA 180
  181 VLAFLVIYCC WKWTFTNLAK RDILPSPVSV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.09691
Match: 1d2tA
Description: Bacterial acid phosphatase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle