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View Structure Prediction Details

Protein: LPP1
Organism: Saccharomyces cerevisiae
Length: 274 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LPP1.

Description E-value Query
Range
Subject
Range
gi|27542785 - gi|27542785|gb|AAO16875.1| PAP2A-GFP fusion protein [synthetic construct]
249.0 [0..5] [268..1]
PLPP1_CAVPO - Phospholipid phosphatase 1 OS=Cavia porcellus GN=PLPP1 PE=2 SV=1
236.0 [0..5] [269..1]
gi|122692411, gi... - gi|81674095|gb|AAI09902.1| Phosphatidic acid phosphatase type 2A [Bos taurus], gi|122692411|ref|NP_0...
236.0 [0..5] [269..1]
gi|3015569 - gi|3015569|gb|AAC32041.1| type-2 phosphatidic acid phosphohydrolase [Homo sapiens]
233.0 [0..5] [268..1]
PLPP1_MOUSE - Phospholipid phosphatase 1 OS=Mus musculus GN=Plpp1 PE=1 SV=1
229.0 [0..5] [268..1]

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Predicted Domain #1
Region A:
Residues: [1-64]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISVMADEKH KEYFKLYYFQ YMIIGLCTIL FLYSEISLVP RGQNIEFSLD DPSISKRYVP  60
   61 NELV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.691 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.590 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.523 d.58.17 Metal-binding domain
View Download 0.523 d.58.17 Metal-binding domain
View Download 0.482 d.57.1 DNA damage-inducible protein DinI
View Download 0.482 d.57.1 DNA damage-inducible protein DinI
View Download 0.465 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.464 d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.458 f.28.1 Nonheme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)

Predicted Domain #2
Region A:
Residues: [65-274]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPLECLILSV GLSNMVVFWT CMFDKDLLKK NRVKRLRERP DGISNDFHFM HTSILCLMLI  60
   61 ISINAALTGA LKLIIGNLRP DFVDRCIPDL QKMSDSDSLV FGLDICKQTN KWILYEGLKS 120
  121 TPSGHSSFIV STMGFTYLWQ RVFTTRNTRS CIWCPLLALV VMVSRVIDHR HHWYDVVSGA 180
  181 VLAFLVIYCC WKWTFTNLAK RDILPSPVSV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.09691
Match: 1d2tA
Description: Bacterial acid phosphatase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle