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View Structure Prediction Details

Protein: VPS72
Organism: Saccharomyces cerevisiae
Length: 810 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VPS72.

Description E-value Query
Range
Subject
Range
gi|16554449, gi|... - gi|16554449|ref|NP_003377.1| zonadhesin isoform 3 [Homo sapiens], gi|12667414|gb|AAK01433.1|AF332977...
2.0E-55 [185..632] [530..996]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTNRSETEA NSQCTMSDEG ADKSLDTNTE FIIQTRSRRS NAGNKLQKLL EQELRDIEST  60
   61 KRQISSYKNG NDDEEDEIGL LFQEDEDDED FEMMAK

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.73
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #2
Region A:
Residues: [97-175]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDDDEGEEKE DETQSIRKEP SQASSEQAAD DLMFSSSESE DSSNENDEDA EEKEIRRQEL  60
   61 LSRKKRNKRL QKGPVVIKK

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.73
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #3
Region A:
Residues: [176-245]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKPKPKSGEA IPRSHHTHEQ LNAETLLLNT RRTSKRSSVM ENTMKVYEKL SKAEKKRKII  60
   61 QERIRKHKEQ 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.73
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #4
Region A:
Residues: [246-321]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESQHMLTQEE RLRIAKETEK LNILSLDKFK EQEVWKKENR LALQKRQKQK FQPNETILQF  60
   61 LSTAWLMTPA MELEDR

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.73
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #5
Region A:
Residues: [322-405]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYWQEQLNKR DKKKKKYPRK PKKNLNLGKQ DASDDKKRES EESIKNDGDV NSLGENSSSV  60
   61 HNQKRIEETS TNDTVEGESS PDAA

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.05
Match: 1ldvA
Description: No description for 1ldvA was found.

Predicted Domain #6
Region A:
Residues: [406-738]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSRVNSDELK PTALPDVTLD AIANKQSTVD EAPNSQPQKN IITNEQKITN VGEPIQNLHN  60
   61 EEIKDEMVSA LESRENTFEN SSPAAQVVSQ RDNSATPTPS NSTGTEDTIL ISPDTDIKGE 120
  121 PEPCLKTEGI ENLSHNVPQE TKSNTDVSFL KQVTFTDHPQ VAIIDTEESP SKKDTANVDE 180
  181 SSAENSLSTQ TYEGPEQLTS RNFVTLYDFP NAPPNLKDFN TNLFGDRWSY TNGLSATQRP 240
  241 QDMKTVFHSI LPSPPQSSVP SPTVDISLDL SALANFPSFG EYDKKIVHQI NTEINKDLEI 300
  301 KIKTQPPTGV FLANGIRKKC LITNKECQYF DPR

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.45
Match: 1ei3A
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [739-810]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGVPYSDVEA YKIIQRIQDP ISKEEGRSDI KRDETTNEDS DDQVRFKWFG FKNGGIYLDL  60
   61 SQRPAKGVPE GF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle