YRC Public Data Repository - Protein Structure Prediction

Protein:	DYN2
Organism:	Saccharomyces cerevisiae
Length:	92 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DYN2.

Description	E-value	Query Range	Subject Range
gi\|38048413, gi\|... - gi\|38048413\|gb\|AAR10109.1\| similar to Drosophila melanogaster ctp [Drosophila yakuba], gi\|195477050\|... gi\|156547267 - gi\|156547267\|ref\|XP_001602336.1\| PREDICTED: similar to cytoplasmic dynein light chain 1 [Nasonia vit... gi\|220951882 - gi\|220951882\|gb\|ACL88484.1\| ctp-PA [synthetic construct] gi\|198469256, gi... - gi\|198469256\|ref\|XP_002134258.1\| GA25980 [Drosophila pseudoobscura pseudoobscura], gi\|198146786\|gb\|E... gi\|194161004, gi... - gi\|195433849\|ref\|XP_002064919.1\| GK15188 [Drosophila willistoni], gi\|194161004\|gb\|EDW75905.1\| GK1518... ctp-PB, ctp-PC, ... - The gene cut up is referred to in FlyBase by the symbol Dmel\ctp (CG6998, FBgn0011760). It is a prot... gi\|121543715 - gi\|121543715\|gb\|ABM55544.1\| dynein light chain 1, cytoplasmic-like protein [Maconellicoccus hirsutus... gi\|190648556, gi... - gi\|194888380\|ref\|XP_001976907.1\| GG18720 [Drosophila erecta], gi\|190648556\|gb\|EDV45834.1\| GG18720 [D... gi\|193687024 - gi\|193687024\|ref\|XP_001947701.1\| PREDICTED: similar to cut up CG6998-PA [Acyrthosiphon pisum] gi\|195386040, gi... - gi\|195386040\|ref\|XP_002051712.1\| GJ17036 [Drosophila virilis], gi\|194148169\|gb\|EDW63867.1\| GJ17036 [... gi\|195340767, gi... - gi\|195340767\|ref\|XP_002036984.1\| GM12359 [Drosophila sechellia], gi\|194131100\|gb\|EDW53143.1\| GM12359... gi\|662195013\|ref... - PREDICTED: dynein light chain 1, cytoplasmic [Diaphorina citri], PREDICTED: dynein light chain 1, cy... gi\|195114680, gi... - gi\|195114680\|ref\|XP_002001895.1\| GI14563 [Drosophila mojavensis], gi\|193912470\|gb\|EDW11337.1\| GI1456... gi\|195034398, gi... - gi\|195034398\|ref\|XP_001988887.1\| GH11410 [Drosophila grimshawi], gi\|193904887\|gb\|EDW03754.1\| GH11410...	4.0E-41	[1..91]	[1..88]
gi\|72044059, gi\|... - gi\|72046933\|ref\|XP_785110.1\| PREDICTED: similar to dynein light chain-2 [Strongylocentrotus purpurat... DYL1_ANTCR - Dynein light chain LC6, flagellar outer arm OS=Anthocidaris crassispina PE=3 SV=1 DYL1_HELCR - Dynein light chain LC6, flagellar outer arm OS=Heliocidaris crassispina PE=3 SV=1	2.0E-40	[1..91]	[1..88]
gi\|73994730, gi\|... - gi\|73994732\|ref\|XP_863417.1\| PREDICTED: similar to dynein, cytoplasmic, light peptide isoform 4 [Can... ENSCJAT00000002182 - null gi\|149720591 - gi\|149720591\|ref\|XP_001488984.1\| PREDICTED: similar to dynein light chain 1 [Equus caballus] gi\|114647338, gi... - gi\|114647340\|ref\|XP_001162616.1\| PREDICTED: dynein light chain 1 isoform 3 [Pan troglodytes], gi\|114... gi\|149437695 - gi\|149437695\|ref\|XP_001506020.1\| PREDICTED: similar to cytoplasmic dynein light chain 1 [Ornithorhyn... gi\|126324339 - gi\|126324339\|ref\|XP_001365264.1\| PREDICTED: similar to cytoplasmic dynein light chain 1 [Monodelphis... DYL1_MOUSE - Dynein light chain 1, cytoplasmic OS=Mus musculus GN=Dynll1 PE=1 SV=1 gi\|194043058 - gi\|194043058\|ref\|XP_001924144.1\| PREDICTED: hypothetical protein [Sus scrofa] gi\|254071303, gi... - gi\|254071305\|gb\|ACT64412.1\| dynein, light chain, LC8-type 1 protein [synthetic construct], gi\|254071... DYL1_RAT - Dynein light chain 1, cytoplasmic OS=Rattus norvegicus GN=Dynll1 PE=1 SV=1 DYL1_BOVIN - Dynein light chain 1, cytoplasmic OS=Bos taurus GN=DYNLL1 PE=1 SV=1 tr\|M3WEC0\|M3WEC0... - Dynein light chain LC8-type 1 OS=Felis catus GN=DYNLL1 PE=4 SV=1 DYL1_RABIT - Dynein light chain 1, cytoplasmic OS=Oryctolagus cuniculus GN=DYNLL1 PE=1 SV=1 DYNLL1 - dynein, light chain, LC8-type 1 DYL1_MACFA - Dynein light chain 1, cytoplasmic OS=Macaca fascicularis GN=DYNLL1 PE=3 SV=1 CCDS9200.1_1 - null gi\|109099555, gi... - gi\|109099555\|ref\|XP_001089481.1\| PREDICTED: similar to dynein, cytoplasmic, light peptide isoform 1 ...	3.0E-40	[1..91]	[1..88]
gi\|114669516, gi... - gi\|114669518\|ref\|XP_001172477.1\| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes], gi\|114... DYNLL2 - dynein, light chain, LC8-type 2 gi\|126307450 - gi\|126307450\|ref\|XP_001363123.1\| PREDICTED: similar to dynein, light chain, LC8-type 2, [Monodelphis... gi\|118100425 - gi\|118100425\|ref\|XP_415908.2\| PREDICTED: hypothetical protein [Gallus gallus] tr\|G3H1E5\|G3H1E5... - Dynein light chain 2, cytoplasmic OS=Cricetulus griseus GN=I79_003970 PE=4 SV=1 DYL2_MOUSE - Dynein light chain 2, cytoplasmic OS=Mus musculus GN=Dynll2 PE=1 SV=1 gi\|149724619 - gi\|149724619\|ref\|XP_001503476.1\| PREDICTED: similar to dynein, light chain, LC8-type 2 [Equus caball... gi\|73966562, gi\|... - gi\|73966570\|ref\|XP_866905.1\| PREDICTED: similar to dynein light chain-2 isoform 8 [Canis familiaris]... DYL2_BOVIN - Dynein light chain 2, cytoplasmic OS=Bos taurus GN=DYNLL2 PE=3 SV=1 gi\|94957771, gi\|... - gi\|94957771\|gb\|ABF47136.1\| dynein light chain dlc8b [Xenopus laevis], gi\|56789627\|gb\|AAH88794.1\| Dyn... tr\|G1TBW9\|G1TBW9... - pep:novel chromosome:oryCun2:19:30124457:30126512:-1 gene:ENSOCUG00000016563 transcript:ENSOCUT00000... gi\|165971122 - gi\|165971122\|gb\|AAI58330.1\| Dynll2 protein [Xenopus tropicalis] tr\|M3WJ42\|M3WJ42... - Dynein light chain LC8-type 2 OS=Felis catus GN=DYNLL2 PE=4 SV=1 gi\|226372022 - gi\|226372022\|gb\|ACO51636.1\| Dynein light chain 2, cytoplasmic [Rana catesbeiana] gi\|224076704 - gi\|224076704\|ref\|XP_002199546.1\| PREDICTED: dynein, light chain, LC8-type 2 [Taeniopygia guttata] DYL2_RAT - Dynein light chain 2, cytoplasmic OS=Rattus norvegicus GN=Dynll2 PE=1 SV=1 CCDS11601.1_1 - null	4.0E-40	[1..91]	[1..88]
gi\|74272647 - gi\|74272647\|gb\|ABA01119.1\| dynein light chain 8 kDa outer arm [Chlamydomonas incerta] DYL1_CHLRE - Dynein 8 kDa light chain, flagellar outer arm OS=Chlamydomonas reinhardtii PE=1 SV=1	7.0E-40	[7..91]	[6..90]
gi\|187023993, gi... - gi\|39581022\|emb\|CAE72503.1\| Hypothetical protein CBG19682 [Caenorhabditis briggsae], gi\|187023993\|em... FL81_18108-RA, C... - RP11979 WBGene00055495 locus:Cre-dlc-1 status:Confirmed, null dlc-1 - status:Confirmed UniProt:Q22799 protein_id:AAC77510.1 gi\|157758877 - gi\|157758877\|ref\|XP_001671782.1\| Hypothetical protein CBG19682 [Caenorhabditis briggsae AF16]	1.0E-39	[1..91]	[1..88]
gi\|7582193 - gi\|7582193\|gb\|AAF64249.1\|AF153718_1 dynein light chain 1 protein DLC-1 [Onchocerca volvulus]	1.0E-37	[13..91]	[1..79]

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Predicted Domain #1

Region A:
Residues: [1-92]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDENKSTPI VKASDITDKL KEDILTISKD ALDKYQLERD IAGTVKKQLD VKYGNTWHVI  60
   61 VGKNFGSYVT HEKGHFVYFY IGPLAFLVFK TA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	258.035458
Match:	1f3cA_
Description:	Dynein light chain 8 (DLC8)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
microtubule motor activity	9.69298846835381	bayes_pls_golite062009
motor activity	5.85494716006373	bayes_pls_golite062009
dynein intermediate chain binding	4.30226487277718	bayes_pls_golite062009
nitric-oxide synthase regulator activity	3.06572632418145	bayes_pls_golite062009
dynein binding	2.90318309608701	bayes_pls_golite062009
cytoskeletal protein binding	2.8232927372914	bayes_pls_golite062009
binding	2.04793419379986	bayes_pls_golite062009
protein binding	1.75479345161448	bayes_pls_golite062009
nucleoside-triphosphatase activity	1.47503021587966	bayes_pls_golite062009
pyrophosphatase activity	1.40860884968216	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.39154744890125	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.38919307572739	bayes_pls_golite062009
ATPase activity, coupled	1.20571334292956	bayes_pls_golite062009
ATPase activity	0.96367371812709	bayes_pls_golite062009
catalytic activity	0.448769452796145	bayes_pls_golite062009
hydrolase activity	0.442050017414837	bayes_pls_golite062009
protein dimerization activity	0.257276734446829	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: