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View Structure Prediction Details

Protein: SIP1
Organism: Saccharomyces cerevisiae
Length: 863 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SIP1.

Description E-value Query
Range
Subject
Range
SIP1 - Alternate beta-subunit of the Snf1p kinase complex, may confer substrate specificity; vacuolar prote...
0.0 [1..863] [1..863]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
4.0E-76 [553..851] [225..484]
gi|11935162 - gi|11935162|gb|AAG41995.1|AF322108_1 SNF1-related kinase complex anchoring protein SIP1 [Lycopersico...
5.0E-41 [707..850] [99..223]
gi|5702015 - gi|5702015|emb|CAB52141.1| GAL83 protein [Solanum tuberosum]
3.0E-40 [706..851] [162..286]
KINB2_ARATH - SNF1-related protein kinase regulatory subunit beta-2 OS=Arabidopsis thaliana GN=KINB2 PE=1 SV=1
2.0E-39 [706..850] [160..285]

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Predicted Domain #1
Region A:
Residues: [1-483]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDISDTSGY LHKQGVLPSV SFICTSFFAC GLTSWKVELS YYIVVAAAMG NSPSTQDPSH  60
   61 STKKEHGHHF HDAFNKDRQG SITSQLFNNR KSTHKRRASH TSEHNGAIPP RMQLLASHDP 120
  121 STDCDGRMSS DTTIDKGPSH LFKKDYSLSS AADVNDTTLA NLTLSDDHDV GAPEEQVKSP 180
  181 SFLSPGPSMA TVKRTKSDLD DLSTLNYTMV DETTENERND KPHHERHRSS IIALKKNLLE 240
  241 SSATASPSPT RSSSVHSASL PALTKTDSID IPVRQPYSKK PSIHAYQYQY LNNDETFSEN 300
  301 SQMDKEGNSD SVDAEAGVLQ SEDMVLNQSL LQNALKKDMQ RLSRVNSSNS MYTAERISHA 360
  361 NNNGNIENNT RNKGNAGGSN DDFTAPISAT AKMMMKLYGD KTLMERDLNK HHNKTKKAQN 420
  421 KKIRSVSNSR RSSFASLHSL QSRKSILTNG LNLQPLHPLH PIINDNESQY SAPQHREISH 480
  481 HSN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [484-677]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SMSSMSSISS TNSTENTLVV LKWKDDGTVA ATTEVFIVST DIASALKEQR ELTLDENASL  60
   61 DSEKQLNPRI RMVYDDVHKE WFVPDLFLPA GIYRLQFSIN GILTHSNFLP TATDSEGNFV 120
  121 NWFEVLPGYH TIEPFRNEAD IDSQVEPTLD EELPKRPELK RFPSSSRKSS YYSAKGVERP 180
  181 STPFSDYRGL SRSS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [678-863]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SINMRDSFVR LKASSLDLMA EVKPERLVYS NEIPNLFNIG DGSTISVKGD SDDVHPQEPP  60
   61 SFTHRVVDCN QDDLFATLQQ GGNIDAETAE AVFLSRYPVP DLPIYLNSSY LNRILNQSNQ 120
  121 NSESHERDEG AINHIIPHVN LNHLLTSSIR DEIISVACTT RYEGKFITQV VYAPCYYKTQ 180
  181 KSQISN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [551-863]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRIRMVYDDV HKEWFVPDLF LPAGIYRLQF SINGILTHSN FLPTATDSEG NFVNWFEVLP  60
   61 GYHTIEPFRN EADIDSQVEP TLDEELPKRP ELKRFPSSSR KSSYYSAKGV ERPSTPFSDY 120
  121 RGLSRSSSIN MRDSFVRLKA SSLDLMAEVK PERLVYSNEI PNLFNIGDGS TISVKGDSDD 180
  181 VHPQEPPSFT HRVVDCNQDD LFATLQQGGN IDAETAEAVF LSRYPVPDLP IYLNSSYLNR 240
  241 ILNQSNQNSE SHERDEGAIN HIIPHVNLNH LLTSSIRDEI ISVACTTRYE GKFITQVVYA 300
  301 PCYYKTQKSQ ISN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.0
Match: 2qlvB
Description: No description for 2qlvB was found.

Predicted functions:

Term Confidence Notes
AMP-activated protein kinase activity 4.78975226545815 bayes_pls_golite062009
binding 2.22611204798233 bayes_pls_golite062009
protein binding 1.50286160643298 bayes_pls_golite062009
cation transmembrane transporter activity 1.21252601175223 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.20869454170074 bayes_pls_golite062009
kinase activity 1.1759320472197 bayes_pls_golite062009
protein kinase activity 1.16294708854294 bayes_pls_golite062009
cation channel activity 1.10928620793874 bayes_pls_golite062009
ligand-gated ion channel activity 1.08920948133636 bayes_pls_golite062009
ligand-gated channel activity 1.08920948133636 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.03266511838083 bayes_pls_golite062009
gated channel activity 0.9831902560942 bayes_pls_golite062009
ion channel activity 0.88499192552319 bayes_pls_golite062009
protein serine/threonine kinase activity 0.726369450752205 bayes_pls_golite062009
transferase activity 0.563590737734601 bayes_pls_golite062009
cytoskeletal protein binding 0.24498703916422 bayes_pls_golite062009
actin binding 0.15943777627145 bayes_pls_golite062009
hydrolase activity 0.0943317805489587 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle