YRC Public Data Repository - Protein Structure Prediction

Protein:	YDR391C
Organism:	Saccharomyces cerevisiae
Length:	232 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDR391C.

Description	E-value	Query Range	Subject Range
YDR391C - Putative protein of unknown function, possibly involved in zinc homeostasis; Bdf1p-dependent transcr... YD391_YEAST - Uncharacterized protein YDR391C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YDR391C ... gi\|207346355 - gi\|207346355\|gb\|EDZ72876.1\| YDR391Cp-like protein [Saccharomyces cerevisiae AWRI1631]	8.0E-92	[1..232]	[1..232]
gi\|25355500 - pir\|\|E95375 probable acetyltransferase [imported] - Sinorhizobium meliloti (strain 1021) magaplasmid... gi\|14524046, gi\|... - gi\|16263362\|ref\|NP_436155.1\| hypothetical protein SMa1660 [Sinorhizobium meliloti 1021], gi\|14524046...	3.0E-44	[32..198]	[16..181]
SPCC550.08 - N-acetyltransferase YJV8_SCHPO - Uncharacterized N-acetyltransferase C550.08 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G...	2.0E-43	[27..190]	[8..184]
gi\|1665837, gi\|2... - gi\|2329856\|emb\|CAA03936.1\| modified puromycin N-acetyl transferase [synthetic construct], gi\|1665837...	2.0E-43	[23..197]	[8..185]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-43	[23..197]	[7..184]
PUAC_STRLP - (P13249) Puromycin N-acetyltransferase (EC 2.3.-.-) gi\|104744460 - gi\|104744460\|gb\|ABF74576.1\| puromycin N-acetyltransferase [Mammalian expression vector pNBio] gi\|239583489 - gi\|239583489\|gb\|ACR82772.1\| puromycin N-acetyltransferase [Cloning vector Mini-Tn4001PSpuro] gi\|104744495 - gi\|104744495\|gb\|ABF74579.1\| puromycin N-acetyltransferase [Mammalian expression vector pCBio] gi\|158534339 - gi\|158534339\|gb\|ABW71928.1\| puromycin N-acetyltransferase [Mammalian expression vector pNBioSec] gi\|239909525 - gi\|239909525\|gb\|ACS32472.1\| puromycin N-acetyltransferase [Human herpesvirus 5] gi\|92918409 - gi\|92918409\|gb\|ABE96683.1\| puromycin N-acetyl transferase [shRNA expression vector pSiRPG] gi\|76364296 - gi\|76364296\|gb\|ABA41666.1\| puromycin-N-acetyltransferase [Firefly luciferase reporter vector pGL4.21... gi\|76364292 - gi\|76364292\|gb\|ABA41663.1\| puromycin-N-acetyltransferase [Firefly luciferase reporter vector pGL4.20... gi\|74273818 - gi\|74273818\|gb\|ABA01557.1\| puromycin N-acetyltransferase [Transfection vector pN-PURO-PTP] gi\|76364324 - gi\|76364324\|gb\|ABA41687.1\| puromycin-N-acetyltransferase [Synthetic Renilla luciferase reporter vect... gi\|76364320 - gi\|76364320\|gb\|ABA41684.1\| puromycin-N-acetyltransferase [Synthetic Renilla luciferase reporter vect... PUAC_STRAD - Puromycin N-acetyltransferase OS=Streptomyces alboniger GN=pac PE=3 SV=2 gi\|76364316 - gi\|76364316\|gb\|ABA41681.1\| puromycin-N-acetyltransferase [Synthetic Renilla luciferase reporter vect... PUAC_STRMI - (P13249) Puromycin N-acetyltransferase (EC 2.3.-.-) gi\|76364300 - gi\|76364300\|gb\|ABA41669.1\| puromycin-N-acetyltransferase [Firefly luciferase reporter vector pGL4.22... gi\|22671671 - gi\|22671671\|gb\|AAN04470.1\| puromycin N-acetyltransferase [Episomal transfection vector pPac] gi\|40804933 - gi\|40804933\|gb\|AAR91728.1\| puromycin-N-acetyltransferase [Cloning vector psiSTRIKE Puromycin] gi\|38260589 - gi\|38260589\|gb\|AAR15422.1\| puromycin N-acetyltransferase [synthetic construct] gi\|53829099 - gi\|53829099\|gb\|AAU94558.1\| puromycin-n-acetyltransferase [pGeneClip Puromycin Vector] gi\|193884058 - gi\|193884058\|dbj\|BAG54841.1\| puromycin phosphotransferase [Cloning vector pInSRT] gi\|193884061 - gi\|193884061\|dbj\|BAG54843.1\| puromycin phosphotransferase [Cloning vector pInSRT-GFPhFDC.SP]	6.0E-43	[23..200]	[7..187]
gi\|13027704 - gi\|13027704\|gb\|AAK08635.1\| puromycin N-acetyltransferase [Integration vector pINT]	9.0E-43	[23..200]	[7..187]
gi\|6063153, gi\|1... - gi\|6063153\|gb\|AAF03159.1\|AF190732_1 NrgA [Bradyrhizobium japonicum], gi\|12620611\|gb\|AAG60887.1\|AF322...	3.0E-42	[34..198]	[19..182]
gi\|10175953, gi\|... - gi\|15615892\|ref\|NP_244196.1\| hypothetical protein BH3330 [Bacillus halodurans C-125], gi\|10175953\|db... gi\|25490834 - pir\|\|B84066 hypothetical protein BH3330 [imported] - Bacillus halodurans (strain C-125)	2.0E-39	[29..198]	[12..194]
gi\|11349598 - pir\|\|G83327 hypothetical protein PA2544 [imported] - Pseudomonas aeruginosa (strain PAO1) gi\|9948602, gi\|1... - gi\|9948602\|gb\|AAG05932.1\|AE004682_4 hypothetical protein PA2544 [Pseudomonas aeruginosa PAO1], gi\|15... gi\|116050488, gi... - gi\|116050488\|ref\|YP_790693.1\| hypothetical protein PA14_31660 [Pseudomonas aeruginosa UCBPP-PA14], g...	3.0E-39	[21..198]	[32..220]

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Predicted Domain #1

Region A:
Residues: [1-109]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFENKLPTP LENNDAKGHM VCTLNKTTDA RRAAETLSIA FSNSPAFHFI CKKILNIPLA  60
   61 EKVPTRTITT DIISPFLDSP YGEISEVNTF DAVAVWSLPP HVPKARSND

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [110-232]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKFNKDFIDD LNARVKQVIP NGINYYYLFC IGKNLNEKGI RGSVRTIFEE YKRRADEENC  60
   61 AIVLEAIAEH AKSVYEYFGF RNYMTFKYGE CEVDSNGNCD PNGEGFTAYL MIYHKDGNKV 120
  121 LKE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.045757
Match:	1cjwA_
Description:	Serotonin N-acetyltranferase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits