YRC Public Data Repository - Protein Structure Prediction

Protein:	YDR391C
Organism:	Saccharomyces cerevisiae
Length:	232 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDR391C.

Description	E-value	Query Range	Subject Range
YDR391C - Putative protein of unknown function, possibly involved in zinc homeostasis; Bdf1p-dependent transcr... YD391_YEAST - Uncharacterized protein YDR391C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YDR391C ... gi\|207346355 - gi\|207346355\|gb\|EDZ72876.1\| YDR391Cp-like protein [Saccharomyces cerevisiae AWRI1631]	8.0E-92	[1..232]	[1..232]
gi\|25355500 - pir\|\|E95375 probable acetyltransferase [imported] - Sinorhizobium meliloti (strain 1021) magaplasmid... gi\|14524046, gi\|... - gi\|16263362\|ref\|NP_436155.1\| hypothetical protein SMa1660 [Sinorhizobium meliloti 1021], gi\|14524046...	3.0E-44	[32..198]	[16..181]
SPCC550.08 - N-acetyltransferase YJV8_SCHPO - Uncharacterized N-acetyltransferase C550.08 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G...	2.0E-43	[27..190]	[8..184]
gi\|1665837, gi\|2... - gi\|2329856\|emb\|CAA03936.1\| modified puromycin N-acetyl transferase [synthetic construct], gi\|1665837...	2.0E-43	[23..197]	[8..185]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-43	[23..197]	[7..184]
PUAC_STRLP - (P13249) Puromycin N-acetyltransferase (EC 2.3.-.-) gi\|104744460 - gi\|104744460\|gb\|ABF74576.1\| puromycin N-acetyltransferase [Mammalian expression vector pNBio] gi\|239583489 - gi\|239583489\|gb\|ACR82772.1\| puromycin N-acetyltransferase [Cloning vector Mini-Tn4001PSpuro] gi\|104744495 - gi\|104744495\|gb\|ABF74579.1\| puromycin N-acetyltransferase [Mammalian expression vector pCBio] gi\|158534339 - gi\|158534339\|gb\|ABW71928.1\| puromycin N-acetyltransferase [Mammalian expression vector pNBioSec] gi\|239909525 - gi\|239909525\|gb\|ACS32472.1\| puromycin N-acetyltransferase [Human herpesvirus 5] gi\|92918409 - gi\|92918409\|gb\|ABE96683.1\| puromycin N-acetyl transferase [shRNA expression vector pSiRPG] gi\|76364296 - gi\|76364296\|gb\|ABA41666.1\| puromycin-N-acetyltransferase [Firefly luciferase reporter vector pGL4.21... gi\|76364292 - gi\|76364292\|gb\|ABA41663.1\| puromycin-N-acetyltransferase [Firefly luciferase reporter vector pGL4.20... gi\|74273818 - gi\|74273818\|gb\|ABA01557.1\| puromycin N-acetyltransferase [Transfection vector pN-PURO-PTP] gi\|76364324 - gi\|76364324\|gb\|ABA41687.1\| puromycin-N-acetyltransferase [Synthetic Renilla luciferase reporter vect... gi\|76364320 - gi\|76364320\|gb\|ABA41684.1\| puromycin-N-acetyltransferase [Synthetic Renilla luciferase reporter vect... PUAC_STRAD - Puromycin N-acetyltransferase OS=Streptomyces alboniger GN=pac PE=3 SV=2 gi\|76364316 - gi\|76364316\|gb\|ABA41681.1\| puromycin-N-acetyltransferase [Synthetic Renilla luciferase reporter vect... PUAC_STRMI - (P13249) Puromycin N-acetyltransferase (EC 2.3.-.-) gi\|76364300 - gi\|76364300\|gb\|ABA41669.1\| puromycin-N-acetyltransferase [Firefly luciferase reporter vector pGL4.22... gi\|22671671 - gi\|22671671\|gb\|AAN04470.1\| puromycin N-acetyltransferase [Episomal transfection vector pPac] gi\|40804933 - gi\|40804933\|gb\|AAR91728.1\| puromycin-N-acetyltransferase [Cloning vector psiSTRIKE Puromycin] gi\|38260589 - gi\|38260589\|gb\|AAR15422.1\| puromycin N-acetyltransferase [synthetic construct] gi\|53829099 - gi\|53829099\|gb\|AAU94558.1\| puromycin-n-acetyltransferase [pGeneClip Puromycin Vector] gi\|193884058 - gi\|193884058\|dbj\|BAG54841.1\| puromycin phosphotransferase [Cloning vector pInSRT] gi\|193884061 - gi\|193884061\|dbj\|BAG54843.1\| puromycin phosphotransferase [Cloning vector pInSRT-GFPhFDC.SP]	6.0E-43	[23..200]	[7..187]
gi\|13027704 - gi\|13027704\|gb\|AAK08635.1\| puromycin N-acetyltransferase [Integration vector pINT]	9.0E-43	[23..200]	[7..187]
gi\|6063153, gi\|1... - gi\|6063153\|gb\|AAF03159.1\|AF190732_1 NrgA [Bradyrhizobium japonicum], gi\|12620611\|gb\|AAG60887.1\|AF322...	3.0E-42	[34..198]	[19..182]
gi\|10175953, gi\|... - gi\|15615892\|ref\|NP_244196.1\| hypothetical protein BH3330 [Bacillus halodurans C-125], gi\|10175953\|db... gi\|25490834 - pir\|\|B84066 hypothetical protein BH3330 [imported] - Bacillus halodurans (strain C-125)	2.0E-39	[29..198]	[12..194]
gi\|11349598 - pir\|\|G83327 hypothetical protein PA2544 [imported] - Pseudomonas aeruginosa (strain PAO1) gi\|9948602, gi\|1... - gi\|9948602\|gb\|AAG05932.1\|AE004682_4 hypothetical protein PA2544 [Pseudomonas aeruginosa PAO1], gi\|15... gi\|116050488, gi... - gi\|116050488\|ref\|YP_790693.1\| hypothetical protein PA14_31660 [Pseudomonas aeruginosa UCBPP-PA14], g...	3.0E-39	[21..198]	[32..220]

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Predicted Domain #1

Region A:
Residues: [1-109]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFENKLPTP LENNDAKGHM VCTLNKTTDA RRAAETLSIA FSNSPAFHFI CKKILNIPLA  60
   61 EKVPTRTITT DIISPFLDSP YGEISEVNTF DAVAVWSLPP HVPKARSND

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.323	a.118.8	TPR-like
View	Download	0.441	c.51.1	Anticodon-binding domain of Class II aaRS
View	Download	0.624	a.24.10	Histidine-containing phosphotransfer domain, HPT domain
View	Download	0.320	a.71.1	Endoplasmic reticulum protein ERP29, C-domain
View	Download	0.444	a.60.13	Putative methyltransferase TM0872, insert domain
View	Download	0.311	a.69.1	C-terminal domain of alpha and beta subunits of F1 ATP synthase
View	Download	0.297	c.84.1	Phosphoglucomutase, first 3 domains
View	Download	0.290	a.83.1	Guanido kinase N-terminal domain
View	Download	0.285	b.34.9	Tudor/PWWP/MBT
View	Download	0.257	a.24.17	Group V grass pollen allergen
View	Download	0.253	a.118.18	Cysteine rich protein B (HcpB)
View	Download	0.235	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.232	a.60.9	lambda integrase-like, N-terminal domain
View	Download	0.231	a.118.11	Cytochrome c oxidase subunit E
View	Download	0.223	a.24.10	Histidine-containing phosphotransfer domain, HPT domain
View	Download	0.214	a.118.1	ARM repeat
View	Download	0.211	a.80.1	DNA polymerase III clamp loader subunits, C-terminal domain
View	Download	0.211	a.24.17	Group V grass pollen allergen
View	Download	0.210	a.74.1	Cyclin-like
View	Download	0.209	d.26.1	FKBP-like
View	Download	0.208	a.39.1	EF-hand
View	Download	0.201	a.80.1	DNA polymerase III clamp loader subunits, C-terminal domain

Predicted Domain #2

Region A:
Residues: [110-232]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKFNKDFIDD LNARVKQVIP NGINYYYLFC IGKNLNEKGI RGSVRTIFEE YKRRADEENC  60
   61 AIVLEAIAEH AKSVYEYFGF RNYMTFKYGE CEVDSNGNCD PNGEGFTAYL MIYHKDGNKV 120
  121 LKE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.045757
Match:	1cjwA_
Description:	Serotonin N-acetyltranferase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits