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View Structure Prediction Details

Protein: SRP101
Organism: Saccharomyces cerevisiae
Length: 621 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SRP101.

Description E-value Query
Range
Subject
Range
gi|172707 - gi|172707|gb|AAA35093.1| SRP receptor alpha-chain homologue
0.0 [1..621] [1..621]
gi|18256022 - gi|18256022|gb|AAH21839.1| Signal recognition particle receptor ('docking protein') [Mus musculus]
0.0 [1..620] [1..634]
SRPRA_CANLF - Signal recognition particle receptor subunit alpha OS=Canis lupus familiaris GN=SRPRA PE=2 SV=2
gi|997 - gi|997|emb|CAA26945.1| signal recognition particle receptor [Canis sp.]
0.0 [1..620] [1..636]
gi|49651655, gi|... - gi|49651655|emb|CAG78596.1| YALI0F23375p [Yarrowia lipolytica], gi|4838528|gb|AAD31027.1|AF132597_1 ...
gi|50556754, gi|... - gi|50556754|ref|XP_505785.1| YALI0F23375p [Yarrowia lipolytica], gi|49651655|emb|CAG78596.1| YlSRP10...
3.0E-95 [1..619] [1..555]
gi|14165547 - gi|14165547|gb|AAH08077.1| SRPR protein [Homo sapiens]
7.0E-91 [1..563] [1..573]
gi|4140392 - gi|4140392|gb|AAD11975.1| signal receptor alpha subunit [Giardia intestinalis]
3.0E-88 [1..619] [1..568]
gi|7269961, gi|2... - gi|7269961|emb|CAB79778.1| signal recognition particle receptor-like protein [Arabidopsis thaliana],...
1.0E-86 [1..620] [1..633]

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Predicted Domain #1
Region A:
Residues: [1-215]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDQLAVFTP QGQVLYQYNC LGKKFSEIQI NSFISQLITS PVTRKESVAN ANTDGFDFNL  60
   61 LTINSEHKNS PSFNALFYLN KQPELYFVVT FAEQTLELNQ ETQQTLALVL KLWNSLHLSE 120
  121 SILKNRQGQN EKNKHNYVDI LQGIEDDLKK FEQYFRIKYE ESIKQDHINP DNFTKNGSVP 180
  181 QSHNKNTKKK LRDTKGKKQS TGNVGSGRKW GRDGG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
signal recognition particle binding 6.13359612945359 bayes_pls_golite062009
ribonucleoprotein binding 3.69979261496156 bayes_pls_golite062009
palmitoyltransferase activity 2.39665981402803 bayes_pls_golite062009
protein-cysteine S-palmitoleyltransferase activity 2.13678994750168 bayes_pls_golite062009
protein-cysteine S-acyltransferase activity 2.13678994750168 bayes_pls_golite062009
protein transporter activity 2.04806587835812 bayes_pls_golite062009
transporter activity 1.71943098913274 bayes_pls_golite062009
SNAP receptor activity 1.47915598483249 bayes_pls_golite062009
protein binding 1.08917223347521 bayes_pls_golite062009
binding 1.08343499631215 bayes_pls_golite062009
substrate-specific transporter activity 0.939682472116899 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.131410992694836 bayes_pls_golite062009
pyrophosphatase activity 0.0936690070284361 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0846345824909659 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0820309452260982 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [216-272]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDEMNHEDA AKLDFSSSNS HNSSQVALDS TINKDSFGDR TEGGDFLIKE IDDLLSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [273-293]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HKDEITSGNE AKNSGYVSTA F

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [363-621]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKALTQILTP GVSVDLLREI QSKRSKKDEE GKCDPYVFSI VGVNGVGKST NLSKLAFWLL  60
   61 QNNFKVLIVA CDTFRSGAVE QLRVHVENLA QLMDDSHVRG SKNKRGKTGN DYVELFEAGY 120
  121 GGSDLVTKIA KQAIKYSRDQ NFDIVLMDTA GRRHNDPTLM SPLKSFADQA KPDKIIMVGE 180
  181 ALVGTDSVQQ AKNFNDAFGK GRNLDFFIIS KCDTVGEMLG TMVNMVYATG IPILFVGVGQ 240
  241 TYTDLRTLSV KWAVNTLMS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 271.491979
Match: 1fts__
Description: Signal recognition particle receptor, FtsY; GTPase domain of the signal recognition particle receptor FtsY
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [294-362]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GFLQKHVLGN KTINESDLKS VLEKLTQQLI TKNVAPEAAD YLTQQVSHDL VGSKTANWTS  60
   61 VENTARESL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 271.491979
Match: 1fts__
Description: Signal recognition particle receptor, FtsY; GTPase domain of the signal recognition particle receptor FtsY
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle