YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: PEX5
Organism: Saccharomyces cerevisiae
Length: 612 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PEX5.

Description E-value Query
Range
Subject
Range
PEX5 - Peroxisomal membrane signal receptor for the C-terminal tripeptide signal sequence (PTS1) of peroxis...
PEX5_YEAST - Peroxisomal targeting signal receptor OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PE...
7.0E-98 [1..612] [1..612]
ogt-1 - status:Confirmed UniProt:O18158 protein_id:AAA62535.2
6.0E-80 [34..584] [15..597]
gi|13775066 - gi|13775066|gb|AAK39123.1|AF363030_1 UDP-N-acetylglucosaminyltransferase [Mus musculus]
2.0E-79 [166..593] [83..502]
gi|5052534 - gi|5052534|gb|AAD38597.1|AF145622_1 BcDNA.GH04245 [Drosophila melanogaster]
3.0E-79 [61..570] [3..503]
OGT1_RAT - UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Rattus norvegicu...
1.0E-78 [115..593] [12..492]
OGT - O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylgluco...
gi|123993895, gi... - gi|224487755|dbj|BAH24112.1| O-linked N-acetylglucosamine (GlcNAc) transferase [synthetic construct]...
2.0E-78 [115..593] [12..492]
gi|15823781 - gi|15823781|dbj|BAB69071.1| short form of PTS1-receptor [Cricetulus griseus]
5.0E-74 [4..610] [9..599]

Back

Predicted Domain #1
Region A:
Residues: [1-195]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVGSCSVGN NPLAQLHKHT QQNKSLQFNQ KNNGRLNESP LQGTNKPGIS EAFISNVNAI  60
   61 SQENMANMQR FINGEPLIDD KRRMEIGPSS GRLPPFSNVH SLQTSANPTQ IKGVNDISHW 120
  121 SQEFQGSNSI QNRNADTGNS EKAWQRGSTT ASSRFQYPNT MMNNYAYASM NSLSGSRLQS 180
  181 PAFMNQQQSG RSKEG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [196-395]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNEQEQQPWT DQFEKLEKEV SENLDINDEI EKEENVSEVE QNKPETVEKE EGVYGDQYQS  60
   61 DFQEVWDSIH KDAEEVLPSE LVNDDLNLGE DYLKYLGGRV NGNIEYAFQS NNEYFNNPNA 120
  121 YKIGCLLMEN GAKLSEAALA FEAAVKEKPD HVDAWLRLGL VQTQNEKELN GISALEECLK 180
  181 LDPKNLEAMK TLAISYINEG 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 525.221849
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [396-471]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YDMSAFTMLD KWAETKYPEI WSRIKQQDDK FQKEKGFTHI DMNAHITKQF LQLANNLSTI  60
   61 DPEIQLCLGL LFYTKD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 525.221849
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peroxisome targeting sequence binding 6.28836842401449 bayes_pls_golite062009
peroxisome matrix targeting signal-1 binding 5.30441166392789 bayes_pls_golite062009
binding 2.14253214573541 bayes_pls_golite062009
protein binding 1.83529176977066 bayes_pls_golite062009
signal sequence binding 1.13935627118933 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [472-531]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFDKTIDCFE SALRVNPNDE LMWNRLGASL ANSNRSEEAI QAYHRALQLK PSFVRARYNL  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 525.221849
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [532-612]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVSSMNIGCF KEAAGYLLSV LSMHEVNTNN KKGDVGSLLN TYNDTVIETL KRVFIAMNRD  60
   61 DLLQEVKPGM DLKRFKGEFS F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 525.221849
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle