YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: EBS1
Organism: Saccharomyces cerevisiae
Length: 884 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EBS1.

Description E-value Query
Range
Subject
Range
EBS1_YEAST - Protein EBS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EBS1 PE=3 SV=1
EBS1 - Protein involved in inhibition of translation and nonsense-mediated decay; interacts with cap bindin...
0.0 [1..884] [1..884]
gi|12240222 - gi|12240222|gb|AAG49579.1|AF324496_1 putative EBS1-like protein [Kluyveromyces lactis]
4.0E-95 [10..347] [8..342]
gi|16550923 - gi|16550923|dbj|BAB71079.1| unnamed protein product [Homo sapiens]
2.0E-72 [49..386] [36..338]
SMG7L_ARATH - Protein SMG7L OS=Arabidopsis thaliana GN=SMG7L PE=2 SV=1
4.0E-59 [16..318] [19..254]
est1 - telomerase regulator Est1
EST1_SCHPO - Telomere elongation protein est1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=est1 PE=1...
1.0E-48 [51..285] [32..252]
gi|18146966 - gi|18146966|dbj|BAB82502.1| cig3 [Nicotiana tabacum]
3.0E-37 [143..294] [3..138]

Back

Predicted Domain #1
Region A:
Residues: [1-80]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPSNTQKED LPTAFNGIKS QLNSILKSNQ LFQDYALLNG FLAFVHSKLN AAILTSIESQ  60
   61 CGKSFAADLD SFDQSSISSI 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.29
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.76684454218635 bayes_pls_golite062009
binding 2.71974493738804 bayes_pls_golite062009
transcription regulator activity 1.96129657517284 bayes_pls_golite062009
protein binding 1.6279032205159 bayes_pls_golite062009
nucleic acid binding 1.62783430593918 bayes_pls_golite062009
DNA binding 1.62663906748938 bayes_pls_golite062009
transcription repressor activity 1.16294866757073 bayes_pls_golite062009
transcription factor activity 0.934706586922936 bayes_pls_golite062009
hydrolase activity 0.488980079329603 bayes_pls_golite062009
transcription factor binding 0.441518464573089 bayes_pls_golite062009
transcription cofactor activity 0.19094857768269 bayes_pls_golite062009
ligase activity 0.102007806594868 bayes_pls_golite062009
signal sequence binding 0.0231142793406351 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [81-264]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDFSWESVHY PIFKWFQMWR NYILFEKENK KQQTKFIDFR KMNSKMLKFF KTVQNFYVNV  60
   61 INTVYKKYDI SVLLPKRIIQ DLKLSDIENT TNVGDILAVK TFNSSSPLAH LIPTLFHRCL 120
  121 LFLGTAYRYK TLLEEISNKY SISNFKKSLD FFRLASLVLP SAGETYSQAG AIFLQTGNLG 180
  181 IAVF

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.29
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [265-480]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFVKGMMTKM PSPVSIKNFG ALMVDNKSSL NRSLHTTIMN TYLQESKGPR TPAKEILEFY  60
   61 FLGLFGSVWS PTSWRDDTKP NQLNNGIKLR HLENALYETM SARYLNNIKT IFHNLIITIG 120
  121 GFHLLLKRRS DVSAKTLKDL RSNELDYLNF AFKYIAHILN DIVKESWSEN PEVSEILGMV 180
  181 RIINCWIKAN PMVLQYSQSN LEFVNALAYL INDIVK

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.29
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [481-884]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKPSPSFSIT EHIPKRTYWF EEDLMVKGLS FVNFQLSDFD DYEKILEMDH SLDRLIGNPP  60
   61 LCDKLSASSE MLLRLQAVVN ISSQLLQNNN CGVEWSDNKS RYIFNKKIGF KETVKNSMKT 120
  121 SKQSNEKAKL QRKNKPSTTN GSISMADLER QMRSSSLDSF SPTMGYSGSS VPMAPDTFNV 180
  181 KPSGTITGNK VNVELLKIEL SGQNADGAIT NISPGYSNAA ISSSNSTDES SFDLNNILSS 240
  241 MQQKHAEKSF AKSMQGVNEQ IPANDVCHQA QRPMQGGLYS SQQPSSMSSL NSAYQNASMP 300
  301 PSASMVSYPY PFLNQQGQGV FPPYNAQNLQ WQSEAYSLKS MNFANPTWLG DQYQTSAPSS 360
  361 AYAQAQRQMF QQPMQQDVGK YMQFPFDAQS NTDSMRGNSR NNMF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle