| Protein: | HST4 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 370 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HST4.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..370] | [1..370] |
|
|
4.0E-73 | [46..370] | [265..576] |
|
|
8.0E-72 | [8..370] | [60..373] |
|
|
3.0E-68 | [69..367] | [195..473] |
|
|
3.0E-68 | [81..370] | [1..241] |
|
|
3.0E-68 | [81..370] | [48..288] |
|
Region A: Residues: [1-112] |
1 11 21 31 41 51
| | | | | |
1 MKQKFVLPIT PPSTAEKKPQ TENRCNENLK PRRLLPQLKK SVRNRKPRLS YRPELNSVFD 60
61 LDAYVDSTHL SKSQRHHMDR DAGFISYALN YSKRMVVVSG AGISVAAGIP DF
|
|
Region B: Residues: [157-215] |
1 11 21 31 41 51
| | | | | |
1 SKNCQPTKFH EMLNEFARDG RLLRLYTQNI DGLDTQLPHL STNVPLAKPI PSTVQLHGS
|
|
Region C: Residues: [285-370] |
1 11 21 31 41 51
| | | | | |
1 HPEGDFIGEI ANNDLKKRID CLIIVGTSLK IPGVKNICRQ FAAKVHANRG IVLYLNTSMP 60
61 PKNVLDSLKF VDLVVLGDCQ HVTSLL
|
| Detection Method: |  |
| Confidence: | 143.035458 |
| Match: | 1iciA_ |
| Description: | AF1676, Sir2 homolog (Sir2-AF1?) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein deacetylase activity | 7.35763207610992 | bayes_pls_golite062009 |
| histone deacetylase activity | 7.26335959347303 | bayes_pls_golite062009 |
| NAD-dependent protein deacetylase activity | 6.47581529902049 | bayes_pls_golite062009 |
| NAD-dependent histone deacetylase activity | 6.47581529902049 | bayes_pls_golite062009 |
| deacetylase activity | 6.37006322346047 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 3.69142507295713 | bayes_pls_golite062009 |
| transcription regulator activity | 2.9155913558118 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 2.82468859281133 | bayes_pls_golite062009 |
| DNA binding | 2.43141001866996 | bayes_pls_golite062009 |
| nucleic acid binding | 2.41433477472968 | bayes_pls_golite062009 |
| transcription repressor activity | 2.24657784428979 | bayes_pls_golite062009 |
| binding | 2.06552694538163 | bayes_pls_golite062009 |
| histone binding | 1.71445510915336 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.64212790017753 | bayes_pls_golite062009 |
| transcription factor activity | 1.30143289828088 | bayes_pls_golite062009 |
| transcription factor binding | 1.14766678956419 | bayes_pls_golite062009 |
| catalytic activity | 0.739210399081789 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.54005617175343 | bayes_pls_golite062009 |
| NAD-dependent histone deacetylase activity (H4-K16 specific) | 0.524001879800456 | bayes_pls_golite062009 |
| protein binding | 0.475479132768057 | bayes_pls_golite062009 |
| tubulin deacetylase activity | 0.191267552550115 | bayes_pls_golite062009 |
| NAD+ ADP-ribosyltransferase activity | 0.0099486881187274 | bayes_pls_golite062009 |
|
Region A: Residues: [113-156] |
1 11 21 31 41 51
| | | | | |
1 RSSEGIFSTV NGGSGKDLFD YNRVYGDESM SLKFNQLMVS LFRL
|
|
Region B: Residues: [216-284] |
1 11 21 31 41 51
| | | | | |
1 IKHMECNKCL NIKPFDPELF KCDDKFDSRT EIIPSCPQCE EYETVRKMAG LRSTGVGKLR 60
61 PRVILYNEV
|
| Detection Method: | |
| Confidence: | 143.035458 |
| Match: | 1iciA_ |
| Description: | AF1676, Sir2 homolog (Sir2-AF1?) |
| Matching Structure (courtesy of the PDB): |
|
