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View Structure Prediction Details

Protein: SLY1
Organism: Saccharomyces cerevisiae
Length: 666 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SLY1.

Description E-value Query
Range
Subject
Range
SLY1 - Hydrophilic protein involved in vesicle trafficking between the ER and Golgi; SM (Sec1/Munc-18) fami...
SLY1_YEAST - Protein SLY1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SLY1 PE=1 SV=1
0.0 [1..666] [1..666]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [1..666] [1..666]
SCFD1_RAT - Sec1 family domain-containing protein 1 OS=Rattus norvegicus GN=Scfd1 PE=1 SV=1
0.0 [6..659] [2..637]
gi|12851714 - gi|12851714|dbj|BAB29141.1| unnamed protein product [Mus musculus]
0.0 [6..659] [2..639]
gi|12276129 - gi|12276129|gb|AAG50273.1|AF319958_1 vesicle transport-related protein [Homo sapiens]
0.0 [11..659] [12..642]
SLY1_DROVI - Protein sly1 homolog OS=Drosophila virilis GN=Slh PE=3 SV=1
0.0 [12..662] [2..652]
Slh-PC, FBpp0307162 - The gene SLY-1 homologous is referred to in FlyBase by the symbol Dmel\Slh (CG3539, FBgn0015816). It...
gi|220947838 - gi|220947838|gb|ACL86462.1| Slh-PC [synthetic construct]
0.0 [12..662] [2..634]
sly1 - SNARE binding protein Sly1
SLY1_SCHPO - Protein sly1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sly1 PE=3 SV=1
0.0 [13..657] [11..639]

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Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVEEIASRK DISLRDMQIS AILKMLFLNK DLNNNDNITT ITDDIFNQQE IIWKVLILDI  60
   61 KSTATISSVL RVNDLLKAGI TVHSLIKQDR SPLPDVPAIY FVSPTKENID IIVNDLKSDK 120
  121 YSEFYINFTS SLPRNLLEDL AQQVSITGKS DKIKQVYDQY 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 392.9897
Match: 1fvfA_
Description: Neuronal Sec1, NSec1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
SNARE binding 4.56428593085019 bayes_pls_golite062009
syntaxin binding 3.46044132736061 bayes_pls_golite062009
binding 2.7837022903231 bayes_pls_golite062009
protein binding 2.77285532000616 bayes_pls_golite062009
syntaxin-1 binding 0.269372794919901 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [161-278]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDFIVTEPEL FSLEISNAYL TLNDPKTTEE EITGLCANIA DGLFNTVLTI NSIPIIRAAK  60
   61 GGPAEIIAEK LGTKLRDFVI NTNSSSTSTL QGNDSLERGV LIILDRNIDF ASMFSHSW

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [562-666]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDAIMDPLNS SQKNLETTDS YLYIDPKITR GSHTRKPKRQ SYNKSLVFVV GGGNYLEYQN  60
   61 LQEWAHSQLH NPKKVMYGST AITTPAEFLN EISRLGASNS SNNDA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 392.9897
Match: 1fvfA_
Description: Neuronal Sec1, NSec1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [279-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IYQCMVFDIF KLSRNTVTIP LESKENGTDN TTAKPLATKK YDIEPNDFFW MENSHLPFPE  60
   61 AAENVEAALN TYKEEAAEIT RKTGVTNISD LDPNSNNDTV QIQEVVKKLP ELTAKKNTID 120
  121 THMNIFAALL SQLE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 392.9897
Match: 1fvfA_
Description: Neuronal Sec1, NSec1
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [413-561]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKSLDTFFEV EQDPGSTKTR SRFLDILKDG KTNNLEDKLR SFIVLYLTST TGLPKDFVQN  60
   61 VENYFKENDY DINALKYVYK LREFMQLSNM SLQNKSLEDG SDSAFKPSNL TLSGIYGLTE 120
  121 GKLQGGVGSL ISGIKKLLPE KKTIPITNV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 392.9897
Match: 1fvfA_
Description: Neuronal Sec1, NSec1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
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