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View Structure Prediction Details

Protein: MTC5
Organism: Saccharomyces cerevisiae
Length: 1148 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTC5.

Description E-value Query
Range
Subject
Range
MTC5 - Protein of unknown function; mtc5 is synthetically sick with cdc13-1
WDR59_YEAST - Maintenance of telomere capping protein 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
0.0 [1..1148] [1..1148]
WDR59_SCHPO - Uncharacterized RWD, RING finger and WD repeat-containing protein C11E3.05 OS=Schizosaccharomyces po...
SPAC11E3.05 - ubiquitin-protein ligase E3
0.0 [3..1142] [211..1313]
gi|15620905 - gi|15620905|dbj|BAB67816.1| KIAA1923 protein [Homo sapiens]
0.0 [170..1143] [18..827]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [5..593] [888..1477]
gi|17225208 - gi|17225208|gb|AAL37300.1|AF323584_1 beta transducin-like protein HET-E2C*40 [Podospora anserina]
0.0 [3..497] [821..1265]

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Predicted Domain #1
Region A:
Residues: [1-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCSSINEGPY NSPTFGKSLS LKVDGGFNAV SINPSGRDIV LASRQGLYII DLDDPFTPPR  60
   61 WLHHITPWQV ADVQWSPHPA KPYWIVSTSN QKAIIWNLAK SSSNAIEFVL HGHSRAITDI 120
  121 NFNPQHPDVL ATCSVDTYVH AWDMRSPHRP FYSTSSWRSA ASQVKWNYKD PNVLASSHGN 180
  181 DIFVWDLRKG STPLCSLKGH VSSVNSIDFN RFKYSEIMSS SNDGTVKFWD YSKSTTESKR 240
  241 TVTTNFPIWR GRYLPFGEGY CIMPMVGGNN AVYLINLCDD DDSEQNKKTK LQPIYAFKGH 300
  301 SDRVIDFLWR SRHTCDGDYD DREFQLVTWS KDCDLKLWPI SDSIYG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.0
Match: 1gg2B_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [347-485]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVNFDRGKRL EEKLPDYDYC SYNKEPENRE NVQKNEFRRL RENFVTTSGL KKNKTNHITW  60
   61 LSGIRMNSAT SQEDLFNETK IQNLGEEVSA IGHKFPKVVF EKISVSTREL CLTLNGPWSE 120
  121 ENPDDYIFLR ISINFPLNY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [486-562]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNKGDPPKFT IEENSNLTMS KRQEILSNLA TIGQKYTDSN LYCLEPCIRF VLGEKVSLED  60
   61 IEEGQEPLLN FDIADHI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [563-832]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFEELSSLDS SYSDSQNPEN LSSQSDIESY KEALVFPDTS NQGLDFGRNL ALDTTPVPNG  60
   61 CGSCWTATGE LFCFFANEKK PEKKQNAIIK LSQKEAGVEK HPFKIEPQVL YDKEVDSSVI 120
  121 TAADELKARP KRYVDTLGLG GGTNGDSRTY FDDETSSDDS FDSVADDWDD ILRNDIIVRT 180
  181 KIPILRGNFK AFSSVHSESG KTVESTKKNK NLVISKNFSS LLSDRKELAL EYLFMDATPE 240
  241 GFARNNALVA EKFDLDEISH CWQILSDMLI 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [833-1063]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DQSDYDPYTT IWNNHPMGIK WFIKEAIVYF ERQQNLQMLA MLCCVILSAR RKKIPARYYG  60
   61 QELENMEGTI VFNDNESQNT SFWKGSDAFS TRSRSSTVTP NFYGNHLRGK NIHGGDNSSI 120
  121 RSDDHHARLR THNTLNGSSK FTEPAQKQGS RAISSSPFHS RMPDIKVELL HDDIIEAYEQ 180
  181 EDLLHLEVSD IPKFQTYIYQ YSKLLFRWGL PLERVKILKV STDFRSSYSS Q

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1064-1148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GIPPNNNKKS PYNGVLTHWI ENNEFGEEKF LARNCNYCDL RVTRSSFICG NCQHVLHSSC  60
   61 ARIWWEIGDE CPSGCGCNCP EMFDA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [968-1062]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGSSKFTEPA QKQGSRAISS SPFHSRMPDI KVELLHDDII EAYEQEDLLH LEVSDIPKFQ  60
   61 TYIYQYSKLL FRWGLPLERV KILKVSTDFR SSYSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1063-1148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QGIPPNNNKK SPYNGVLTHW IENNEFGEEK FLARNCNYCD LRVTRSSFIC GNCQHVLHSS  60
   61 CARIWWEIGD ECPSGCGCNC PEMFDA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.05
Match: 2d8tA
Description: No description for 2d8tA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle