| Protein: | MTC5 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1148 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTC5.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1148] | [1..1148] |
|
|
0.0 | [3..1142] | [211..1313] |
|
|
0.0 | [170..1143] | [18..827] |
|
|
0.0 | [5..593] | [888..1477] |
|
|
0.0 | [3..497] | [821..1265] |
|
Region A: Residues: [1-346] |
1 11 21 31 41 51
| | | | | |
1 MCSSINEGPY NSPTFGKSLS LKVDGGFNAV SINPSGRDIV LASRQGLYII DLDDPFTPPR 60
61 WLHHITPWQV ADVQWSPHPA KPYWIVSTSN QKAIIWNLAK SSSNAIEFVL HGHSRAITDI 120
121 NFNPQHPDVL ATCSVDTYVH AWDMRSPHRP FYSTSSWRSA ASQVKWNYKD PNVLASSHGN 180
181 DIFVWDLRKG STPLCSLKGH VSSVNSIDFN RFKYSEIMSS SNDGTVKFWD YSKSTTESKR 240
241 TVTTNFPIWR GRYLPFGEGY CIMPMVGGNN AVYLINLCDD DDSEQNKKTK LQPIYAFKGH 300
301 SDRVIDFLWR SRHTCDGDYD DREFQLVTWS KDCDLKLWPI SDSIYG
|
| Detection Method: |  |
| Confidence: | 74.0 |
| Match: | 1gg2B_ |
| Description: | beta1-subunit of the signal-transducing G protein heterotrimer |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [347-485] |
1 11 21 31 41 51
| | | | | |
1 KVNFDRGKRL EEKLPDYDYC SYNKEPENRE NVQKNEFRRL RENFVTTSGL KKNKTNHITW 60
61 LSGIRMNSAT SQEDLFNETK IQNLGEEVSA IGHKFPKVVF EKISVSTREL CLTLNGPWSE 120
121 ENPDDYIFLR ISINFPLNY
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.403 | 0.295 | fungal-type vacuole membrane | b.55.1 | PH domain-like |
| View | Download | 0.375 | 0.049 | fungal-type vacuole membrane | b.82.3 | cAMP-binding domain-like |
| View | Download | 0.298 | 0.039 | fungal-type vacuole membrane | d.185.1 | LuxS/MPP-like metallohydrolase |
| View | Download | 0.364 | 0.006 | fungal-type vacuole membrane | b.54.1 | Core binding factor beta, CBF |
| View | Download | 0.390 | N/A | N/A | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.290 | N/A | N/A | d.79.1 | YjgF-like |
| View | Download | 0.283 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.279 | N/A | N/A | c.50.1 | Macro domain-like |
| View | Download | 0.271 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.267 | N/A | N/A | c.50.1 | Macro domain-like |
| View | Download | 0.267 | N/A | N/A | d.198.2 | Arp2/3 complex subunits |
| View | Download | 0.243 | N/A | N/A | d.198.2 | Arp2/3 complex subunits |
| View | Download | 0.233 | N/A | N/A | d.74.1 | Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) |
| View | Download | 0.229 | N/A | N/A | a.118.14 | FliG |
| View | Download | 0.229 | N/A | N/A | d.74.1 | Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) |
| View | Download | 0.224 | N/A | N/A | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.222 | N/A | N/A | d.142.1 | Glutathione synthetase ATP-binding domain-like |
| View | Download | 0.216 | N/A | N/A | d.77.1 | Ribosomal protein L5 |
| View | Download | 0.201 | N/A | N/A | a.4.6 | C-terminal effector domain of the bipartite response regulators |
|
Region A: Residues: [486-562] |
1 11 21 31 41 51
| | | | | |
1 PNKGDPPKFT IEENSNLTMS KRQEILSNLA TIGQKYTDSN LYCLEPCIRF VLGEKVSLED 60
61 IEEGQEPLLN FDIADHI
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.417 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.387 | a.74.1 | Cyclin-like |
| View | Download | 0.391 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.391 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.487 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.487 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.417 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.391 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.391 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.387 | a.74.1 | Cyclin-like |
| View | Download | 0.367 | a.51.1 | Cytochrome c oxidase subunit h |
| View | Download | 0.362 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.361 | a.28.1 | ACP-like |
| View | Download | 0.360 | a.74.1 | Cyclin-like |
| View | Download | 0.353 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.342 | a.74.1 | Cyclin-like |
| View | Download | 0.338 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.327 | a.64.1 | Saposin |
| View | Download | 0.325 | a.28.2 | Colicin E immunity proteins |
| View | Download | 0.323 | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.322 | a.74.1 | Cyclin-like |
| View | Download | 0.319 | d.15.1 | Ubiquitin-like |
| View | Download | 0.314 | d.39.1 | Dynein light chain 8 (DLC8) |
| View | Download | 0.312 | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.306 | a.5.2 | UBA-like |
| View | Download | 0.299 | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.296 | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.285 | a.5.3 | N-terminal domain of phosphatidylinositol transfer protein sec14p |
| View | Download | 0.281 | a.60.2 | RuvA domain 2-like |
| View | Download | 0.278 | a.74.1 | Cyclin-like |
| View | Download | 0.276 | a.4.1 | Homeodomain-like |
| View | Download | 0.273 | a.159.2 | FF domain |
| View | Download | 0.272 | a.74.1 | Cyclin-like |
| View | Download | 0.271 | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.268 | a.2.3 | Chaperone J-domain |
| View | Download | 0.268 | a.28.2 | Colicin E immunity proteins |
| View | Download | 0.267 | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.261 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.252 | a.69.3 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain |
| View | Download | 0.244 | a.74.1 | Cyclin-like |
| View | Download | 0.240 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.237 | a.39.1 | EF-hand |
| View | Download | 0.236 | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.229 | a.74.1 | Cyclin-like |
| View | Download | 0.225 | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.217 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.217 | a.74.1 | Cyclin-like |
| View | Download | 0.214 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.214 | a.153.1 | Nuclear receptor coactivator interlocking domain |
| View | Download | 0.211 | a.159.1 | Protein serine/threonine phosphatase 2C, C-terminal domain |
| View | Download | 0.209 | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.205 | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.205 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.201 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
|
Region A: Residues: [563-832] |
1 11 21 31 41 51
| | | | | |
1 DFEELSSLDS SYSDSQNPEN LSSQSDIESY KEALVFPDTS NQGLDFGRNL ALDTTPVPNG 60
61 CGSCWTATGE LFCFFANEKK PEKKQNAIIK LSQKEAGVEK HPFKIEPQVL YDKEVDSSVI 120
121 TAADELKARP KRYVDTLGLG GGTNGDSRTY FDDETSSDDS FDSVADDWDD ILRNDIIVRT 180
181 KIPILRGNFK AFSSVHSESG KTVESTKKNK NLVISKNFSS LLSDRKELAL EYLFMDATPE 240
241 GFARNNALVA EKFDLDEISH CWQILSDMLI
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [833-1063] |
1 11 21 31 41 51
| | | | | |
1 DQSDYDPYTT IWNNHPMGIK WFIKEAIVYF ERQQNLQMLA MLCCVILSAR RKKIPARYYG 60
61 QELENMEGTI VFNDNESQNT SFWKGSDAFS TRSRSSTVTP NFYGNHLRGK NIHGGDNSSI 120
121 RSDDHHARLR THNTLNGSSK FTEPAQKQGS RAISSSPFHS RMPDIKVELL HDDIIEAYEQ 180
181 EDLLHLEVSD IPKFQTYIYQ YSKLLFRWGL PLERVKILKV STDFRSSYSS Q
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1064-1148] |
1 11 21 31 41 51
| | | | | |
1 GIPPNNNKKS PYNGVLTHWI ENNEFGEEKF LARNCNYCDL RVTRSSFICG NCQHVLHSSC 60
61 ARIWWEIGDE CPSGCGCNCP EMFDA
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.410 | 0.247 | fungal-type vacuole membrane | d.58.17 | Metal-binding domain |
| View | Download | 0.493 | N/A | N/A | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.324 | N/A | N/A | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.299 | N/A | N/A | d.58.17 | Metal-binding domain |
| View | Download | 0.242 | N/A | N/A | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.241 | N/A | N/A | d.58.24 | CheY-binding domain of CheA |
| View | Download | 0.230 | N/A | N/A | d.52.1 | Alpha-lytic protease prodomain |
| View | Download | 0.217 | N/A | N/A | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.202 | N/A | N/A | d.74.2 | C-terminal domain of arginine repressor |
|
Region A: Residues: [968-1062] |
1 11 21 31 41 51
| | | | | |
1 NGSSKFTEPA QKQGSRAISS SPFHSRMPDI KVELLHDDII EAYEQEDLLH LEVSDIPKFQ 60
61 TYIYQYSKLL FRWGLPLERV KILKVSTDFR SSYSS
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1063-1148] |
1 11 21 31 41 51
| | | | | |
1 QGIPPNNNKK SPYNGVLTHW IENNEFGEEK FLARNCNYCD LRVTRSSFIC GNCQHVLHSS 60
61 CARIWWEIGD ECPSGCGCNC PEMFDA
|
| Detection Method: | |
| Confidence: | 2.05 |
| Match: | 2d8tA |
| Description: | No description for 2d8tA was found. |
