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View Structure Prediction Details

Protein: SWF1
Organism: Saccharomyces cerevisiae
Length: 336 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SWF1.

Description E-value Query
Range
Subject
Range
SWF1 - Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on all SNAREs; member of...
SWF1_YEAST - Palmitoyltransferase SWF1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SWF1 PE=1 SV=2
7.0E-66 [1..336] [1..336]
gi|12698041 - gi|12698041|dbj|BAB21839.1| KIAA1748 protein [Homo sapiens]
2.0E-51 [9..289] [3..299]
ZDHC5_MOUSE - Palmitoyltransferase ZDHHC5 OS=Mus musculus GN=Zdhhc5 PE=1 SV=1
3.0E-49 [39..289] [1..256]
gi|220943582 - gi|220943582|gb|ACL84334.1| Hip14-PA [synthetic construct]
FBpp0305754, Hip... - The gene Huntingtin-interacting protein 14 is referred to in FlyBase by the symbol Dmel\Hip14 (CG601...
3.0E-47 [3..303] [297..614]
ZDH23_ARATH - Probable protein S-acyltransferase 6 OS=Arabidopsis thaliana GN=PAT06 PE=2 SV=1
6.0E-45 [11..277] [45..293]

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Predicted Domain #1
Region A:
Residues: [1-118]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWNLLFVLL IGFVVLILLS PVFKSTWPFS TFYRNVFQPF LVDDQKYRWK LHLVPLFYTS  60
   61 IYLYLVYTYH MRVESTIKNE LFLLERILIV PIIILPPVAL GILAMVSRAE DSKDHKSG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.860 a.7.1 Spectrin repeat
View Download 0.763 a.47.2 t-snare proteins
View Download 0.669 a.133.1 Phospholipase A2, PLA2
View Download 0.662 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.659 a.7.8 GAT domain

Predicted Domain #2
Region A:
Residues: [119-206]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STEEYPYDYL LYYPAIKCST CRIVKPARSK HCSICNRCVL VADHHCIWIN NCIGKGNYLQ  60
   61 FYLFLISNIF SMCYAFLRLW YISLNSTS

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 34.920819
Match: PF01529
Description: DHHC zinc finger domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
histone acetyltransferase activity 2.27787208911046 bayes_pls_golite062009
lysine N-acetyltransferase activity 2.27787208911046 bayes_pls_golite062009
binding 2.26426010117912 bayes_pls_golite062009
protein transporter activity 1.41828558915713 bayes_pls_golite062009
protein binding 1.35218914294914 bayes_pls_golite062009
transporter activity 1.33264421804057 bayes_pls_golite062009
cytoskeletal protein binding 1.33198351552985 bayes_pls_golite062009
phosphoinositide binding 1.19034196920111 bayes_pls_golite062009
phospholipid binding 1.09010543599677 bayes_pls_golite062009
transcription regulator activity 1.00368169716135 bayes_pls_golite062009
substrate-specific transporter activity 0.929797787738847 bayes_pls_golite062009
DNA binding 0.919146751776512 bayes_pls_golite062009
nucleic acid binding 0.788911508084267 bayes_pls_golite062009
N-acyltransferase activity 0.565596821175093 bayes_pls_golite062009
N-acetyltransferase activity 0.514633973697725 bayes_pls_golite062009
histone binding 0.335672312059968 bayes_pls_golite062009
0.308979985902751 bayes_pls_golite062009
phosphatidylinositol binding 0.251953910109229 bayes_pls_golite062009
ligase activity 0.161281682592326 bayes_pls_golite062009
transcription factor activity 0.0724499929149738 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.0446344906851331 bayes_pls_golite062009
pyrophosphatase activity 0.00643795263722946 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [207-336]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLPRAVLTLT ILCGCFTIIC AIFTYLQLAI VKEGMTTNEQ DKWYTIQEYM REGKLVRSLD  60
   61 DDCPSWFFKC TEQKDDAAEP LQDQHVTFYS TNAYDHKHYN LTHYITIKDA SEIPNIYDKG 120
  121 TFLANLTDLI 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.578 0.304 integral to membrane a.47.2 t-snare proteins
View Download 0.518 0.054 integral to membrane f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.568 0.002 integral to membrane a.1.1 Globin-like
View Download 0.509 0.001 integral to membrane a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.571 0.000 integral to membrane a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View Download 0.578 N/A N/A a.47.2 t-snare proteins
View Download 0.571 N/A N/A a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View Download 0.568 N/A N/A a.1.1 Globin-like
View Download 0.518 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.509 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.499 N/A N/A a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.461 N/A N/A a.19.1 Fertilization protein
View Download 0.453 N/A N/A a.25.1 Ferritin-like
View Download 0.448 N/A N/A a.72.1 Functional domain of the splicing factor Prp18
View Download 0.440 N/A N/A a.1.1 Globin-like
View Download 0.428 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.414 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.398 N/A N/A a.24.3 Cytochromes
View Download 0.396 N/A N/A a.24.3 Cytochromes
View Download 0.382 N/A N/A a.74.1 Cyclin-like
View Download 0.379 N/A N/A a.19.1 Fertilization protein
View Download 0.368 N/A N/A a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.364 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.364 N/A N/A a.26.1 4-helical cytokines
View Download 0.362 N/A N/A a.63.1 Apolipophorin-III
View Download 0.360 N/A N/A f.18.1 F1F0 ATP synthase subunit A
View Download 0.352 N/A N/A a.1.1 Globin-like
View Download 0.343 N/A N/A a.24.4 Hemerythrin
View Download 0.322 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.312 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.307 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.300 N/A N/A a.25.1 Ferritin-like
View Download 0.293 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.280 N/A N/A a.74.1 Cyclin-like
View Download 0.278 N/A N/A a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.274 N/A N/A a.69.1 C-terminal domain of alpha and beta subunits of F1 ATP synthase
View Download 0.263 N/A N/A a.47.2 t-snare proteins
View Download 0.260 N/A N/A a.182.1 GatB/YqeY domain
View Download 0.255 N/A N/A a.74.1 Cyclin-like
View Download 0.243 N/A N/A a.70.1 N-terminal domain of the delta subunit of the F1F0-ATP synthase
View Download 0.243 N/A N/A a.24.2 Aspartate receptor, ligand-binding domain
View Download 0.235 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.226 N/A N/A a.7.1 Spectrin repeat
View Download 0.224 N/A N/A a.7.5 Tubulin chaperone cofactor A
View Download 0.222 N/A N/A d.2.1 Lysozyme-like
View Download 0.222 N/A N/A a.21.1 HMG-box
View Download 0.213 N/A N/A a.22.1 Histone-fold
View Download 0.213 N/A N/A a.61.1 Retroviral matrix proteins
View Download 0.209 N/A N/A a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.205 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.204 N/A N/A a.7.7 BAG domain
View Download 0.204 N/A N/A a.118.8 TPR-like
View Download 0.200 N/A N/A a.47.1 STAT
View Download 0.200 N/A N/A e.34.1 NSP3 homodimer


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle