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View Structure Prediction Details

Protein: NRP1
Organism: Saccharomyces cerevisiae
Length: 719 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NRP1.

Description E-value Query
Range
Subject
Range
gi|288590 - gi|288590|emb|CAA48159.1| ARP [Saccharomyces cerevisiae]
0.0 [1..719] [1..719]
YE04_SCHPO - Uncharacterized RNA-binding protein C17H9.04c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)...
SPAC17H9.04c - RNA-binding protein
0.0 [21..457] [39..432]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-52 [373..600] [2246..2460]
SUA_ARATH - SUPPRESSOR OF ABI3-5 OS=Arabidopsis thaliana GN=SUA PE=1 SV=2
1.0E-37 [204..387] [250..410]
gi|2642500 - gi|2642500|gb|AAC47842.1| CG2 [Plasmodium falciparum]
3.0E-33 [376..611] [2190..2411]
gi|7494203 - pir||T18435 hypothetical protein C0390w - malaria parasite (Plasmodium falciparum)
gi|16805183, gi|... - gi|3649764|emb|CAB11113.1| N2227-like protein, putative [Plasmodium falciparum 3D7], gi|16805183|ref...
1.0E-32 [379..619] [236..481]
gi|9988773 - gi|9988773|gb|AAG10785.1| carbamoyl phosphate synthetase II [Plasmodium berghei]
1.0E-29 [384..637] [1051..1315]

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Predicted Domain #1
Region A:
Residues: [1-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHYVVLELQV AHLPDTPKDQ CRIANIAFQI VNAETLVCHY GTNSLPSIEV NGTTKSLESA  60
   61 MVQLDKDIHD VIGNDDFVLV SLYSTWHIRV TLPRQARDDG FILTSYLQHP KVFDLWKEFD 120
  121 RWCVNHPEIL GQKKAISNNN CNTKSISINA AKNTKDLDEI VRILEVSIPT EEA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.396 d.19.1 MHC antigen-recognition domain
View Download 0.373 d.95.2 Homing endonucleases
View Download 0.396 c.55.4 Translational machinery components
View Download 0.316 d.112.1 Phoshotransferase/anion transport protein
View Download 0.481 d.58.22 TRADD, N-terminal domain
View Download 0.276 b.51.1 ValRS/IleRS/LeuRS editing domain
View Download 0.272 d.202.1 Transcription factor NusA, N-terminal domain
View Download 0.246 d.110.4 SNARE-like
View Download 0.244 d.3.1 Cysteine proteinases
View Download 0.241 d.58.26 GHMP Kinase, C-terminal domain

Predicted Domain #2
Region A:
Residues: [174-317]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSVPEIYSLL KRTTDILIQL HKKCTSPEDM ESVLTKPYDS HTDIRAFLQE KSKILYMNNL  60
   61 PPDTTQSELE SWFTQYGVRP VGFWTVKNIV EDTSNVNNNW SLNNSPYVED QDSISGFVVF 120
  121 QTHEEATEVL ALNGRSILSN LANT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.69897
Match: 1fxlA_
Description: Hu antigen D (Hud)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [318-463]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQPRVVEHVL ELQPSSTGVL DKAQEILSPF PQSKNKPRPG DWNCPSCGFS NFQRRTACFR  60
   61 CSFPAPSNSQ IHTANSNNNV NSSRNNLNNR VNSGSSSNIS NTAANHPYGA PEFNMIANNT 120
  121 PAALTYNRAH FPAITPLSRQ NSLNMA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.262 0.000 cytoplasm d.190.1 Chorismate lyase

Predicted Domain #4
Region A:
Residues: [464-582]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSNSGSPIII ADHFSGNNNI APNYRYNNNI NNNNNNINNM TNNRYNINNN INGNGNGNGN  60
   61 NSNNNNNHNN NHNNNHHNGS INSNSNTNNN NNNNNGNNSN NCNSNIGMGG CGSNMPFRA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [583-719]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDWKCSTCTY HNFAKNVVCL RCGGPKSISG DASETNHYID SSTFGPASRT PSNNNISVNT  60
   61 NGGSNAGRTD GNDNKGRDIS LMEFMSPPLS MATKSMKEGD GNGSSFNEFK SDKANVNFSN 120
  121 VGDNSAFGNG FNSSIRW

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle