YRC Public Data Repository - Protein Structure Prediction

Protein:	HMRA2
Organism:	Saccharomyces cerevisiae
Length:	119 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HMRA2.

Description	E-value	Query Range	Subject Range
gi\|4589880 - gi\|4589880\|dbj\|BAA76903.1\| homeobox 9 [Nicotiana tabacum]	4.0E-32	[6..110]	[211..315]
gi\|8920427, gi\|1... - gi\|8920427\|emb\|CAB96425.1\| OCL5 protein [Zea mays], gi\|162462636\|ref\|NP_001105127.1\| OCL5 protein [Z...	6.0E-31	[7..116]	[74..179]
gi\|19072102 - gi\|19072102\|dbj\|BAB85750.1\| Roc1 [Oryza sativa]	7.0E-31	[7..116]	[76..181]
MEIS3 - Meis homeobox 3	1.0E-30	[1..106]	[232..337]
gi\|42542926, gi\|... - gi\|42542926\|gb\|AAH66375.1\| Myeloid ecotropic viral integration site 2.1 [Danio rerio], gi\|11877245\|e...	2.0E-30	[3..113]	[243..350]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-30	[13..113]	[221..321]
gi\|195330083, gi... - gi\|195330083\|ref\|XP_002031738.1\| GM26167 [Drosophila sechellia], gi\|194120681\|gb\|EDW42724.1\| GM26167... gi\|195499804, gi... - gi\|195499804\|ref\|XP_002097102.1\| GE24684 [Drosophila yakuba], gi\|194183203\|gb\|EDW96814.1\| GE24684 [D... gi\|194740910, gi... - gi\|194740910\|ref\|XP_001952933.1\| GF17520 [Drosophila ananassae], gi\|190625992\|gb\|EDV41516.1\| GF17520... gi\|190652371, gi... - gi\|194902305\|ref\|XP_001980668.1\| GG17283 [Drosophila erecta], gi\|190652371\|gb\|EDV49626.1\| GG17283 [D... hth-PC - The gene homothorax is referred to in FlyBase by the symbol Dmel\hth (CG17117, FBgn0001235). It is a... gi\|195571977, gi... - gi\|195571977\|ref\|XP_002103977.1\| GD20718 [Drosophila simulans], gi\|194199904\|gb\|EDX13480.1\| GD20718 ...	2.0E-30	[3..116]	[330..443]
HXA10_MOUSE, HXA... - (P31310) Homeobox protein Hox-A10 (Hox-1.8), (P31310) Homeobox protein Hox-A10 (Hox-1.8)	3.0E-30	[3..110]	[290..394]

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Predicted Domain #1

Region A:
Residues: [1-119]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSIENDRSN YQLTQKNKSA DGLVFNVVTQ DMINKSTKPY RGHRFTKENV RILESWFAKN  60
   61 IENPYLDTKG LENLMKNTSL SRIQIKNWVS NRRRKEKTIT IAPELADLLS GEPLAKKKE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	387.54902
Match:	1mnmC_
Description:	mat alpha2 Homeodomain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.747931031167827	bayes_pls_golite062009
transcription regulator activity	0.252872110309073	bayes_pls_golite062009
nucleic acid binding	0.245470553570125	bayes_pls_golite062009
DNA binding	0.209111028952582	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: