YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: RSC6
Organism: Saccharomyces cerevisiae
Length: 483 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RSC6.

Description E-value Query
Range
Subject
Range
RSC6 - Component of the RSC chromatin remodeling complex; essential for mitotic growth; homolog of SWI/SNF ...
RSC6_YEAST - Chromatin structure-remodeling complex protein RSC6 OS=Saccharomyces cerevisiae (strain ATCC 204508 ...
0.0 [1..483] [1..483]
gi|114644841, gi... - gi|114644841|ref|XP_001155587.1| PREDICTED: SWI/SNF-related matrix-associated actin-dependent regula...
gi|4566530 - gi|4566530|gb|AAD23390.1|AF109733_1 SWI/SNF-related, matrix-associated, actin-dependent regulator of...
gi|109096590 - gi|109096590|ref|XP_001110916.1| PREDICTED: similar to SWI/SNF-related matrix-associated actin-depen...
tr|G3HX65|G3HX65... - SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 OS=Cri...
0.0 [14..473] [67..432]
gi|1549249, gi|1... - gi|1549249|gb|AAC52794.1| SWI/SNF complex 60 KDa subunit [Mus musculus], gi|13937377|ref|NP_114030.1...
0.0 [14..473] [90..454]
SMRD2_RAT - SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 OS=Rat...
0.0 [6..474] [126..511]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [6..474] [126..511]
gi|195566518, gi... - gi|195566518|ref|XP_002106827.1| GD15903 [Drosophila simulans], gi|194204219|gb|EDX17795.1| GD15903 ...
Bap60-PA - The gene Brahma associated protein 60kD is referred to in FlyBase by the symbol Dmel\Bap60 (CG4303, ...
0.0 [8..473] [125..494]

Back

Predicted Domain #1
Region A:
Residues: [1-266]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTQTNPVPV TYPTDAYIPT YLPDDKVSNL ADLKKLIEMD SRLDLYLTRR RLDTSINLPT  60
   61 NTKTKDHPPN KEMLRIYVYN TTESSPRSDS GTPADSGKTT WTLRIEGKLL HESANGKHPF 120
  121 SEFLEGVAVD FKRLKPLGMG KKRKRDSSLS LPLNLQQPEY NDQDSTMGDN DNGEDEDSAE 180
  181 AESREEIVDA LEWNYDENNV VEFDGIDIKR QGKDNLRCSI TIQLRGVDGG KVQYSPNLAT 240
  241 LIGMQTGSVN DAVYSIYKYI LINNLF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [267-326]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTEQTEAQDG SNDAEDSSNE NNNKNGAGDD DGVEGSTPKD KPELGEVKLD SLLQKVLDTN  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [327-483]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAHLPLMNVV QTVNKLVSPL PPIILDYTID LSKDTTYGAT TLDVDVSHIL HQPQPQPNLQ  60
   61 KEEETDAEDT AKLREITKLA LQLNSSAQKY QFFHELSLHP RETLTHYLWS SKQNELVLQG 120
  121 DQYFNEDAAR TSDIYSNNNN DRSLMGNISL LYSQGRL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [214-378]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNLRCSITIQ LRGVDGGKVQ YSPNLATLIG MQTGSVNDAV YSIYKYILIN NLFVTEQTEA  60
   61 QDGSNDAEDS SNENNNKNGA GDDDGVEGST PKDKPELGEV KLDSLLQKVL DTNAAHLPLM 120
  121 NVVQTVNKLV SPLPPIILDY TIDLSKDTTY GATTLDVDVS HILHQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.69897
Match: 1uhrA
Description: Solution structure of the SWIB domain of mouse BRG1-associated factor 60a
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.01592136607858 bayes_pls_golite062009
basal transcription repressor activity 3.09418413549897 bayes_pls_golite062009
binding 2.67987108623459 bayes_pls_golite062009
transcription coactivator activity 2.58234407051051 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 2.32480271621458 bayes_pls_golite062009
transcription repressor activity 1.98538788872171 bayes_pls_golite062009
transcription activator activity 1.83085389017135 bayes_pls_golite062009
transcription factor binding 1.73032563380905 bayes_pls_golite062009
transcription cofactor activity 1.60414428986898 bayes_pls_golite062009
protein binding 1.58138506346812 bayes_pls_golite062009
structural molecule activity 1.28917299936669 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.06026105710513 bayes_pls_golite062009
catalytic activity 0.121624777548864 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [379-483]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQPQPNLQKE EETDAEDTAK LREITKLALQ LNSSAQKYQF FHELSLHPRE TLTHYLWSSK  60
   61 QNELVLQGDQ YFNEDAARTS DIYSNNNNDR SLMGNISLLY SQGRL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle