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View Structure Prediction Details

Protein: SYP1
Organism: Saccharomyces cerevisiae
Length: 870 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SYP1.

Description E-value Query
Range
Subject
Range
SYP1_YEAST - Suppressor of yeast profilin deletion OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SY...
SYP1 - Protein of unknown function that is involved in endocytic site formation; may regulate assembly and ...
0.0 [1..870] [1..870]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
4.0E-86 [207..870] [5..668]
SYP1_SCHPO - Cytoskeletal protein syp1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=syp1 PE=1 SV=1
SPBC4C3.06 - actin cytoskeletal protein Syp1
4.0E-50 [5..799] [6..742]
SLP1_CLOTM, SLAP... - (Q06852) Cell surface glycoprotein 1 precursor (Outer layer protein B) (S-layer protein 1), Cell sur...
1.0E-49 [66..659] [761..1367]
gi|16554449, gi|... - gi|16554449|ref|NP_003377.1| zonadhesin isoform 3 [Homo sapiens], gi|12667414|gb|AAK01433.1|AF332977...
1.0E-45 [157..722] [471..1029]

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Predicted Domain #1
Region A:
Residues: [1-150]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEQRTKYAD SILTTKSPYE ATETIRIRLS QVKLLNKDFY LLFKELANLK RNYAQQLRKI  60
   61 IAENEDITKI LNAQMIESNV LTPQEMSAFR FNSLGELRNV WDTVIEELKS DLKSSTEYYN 120
  121 TLDQQVVREL KESVENNTSW RESKDLHSKL 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [151-377]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKNAASIEHY SKNNENSSHL EEARRQWDQQ SPYLFELFET IDYNRLDTLK NCMLRFQTSF  60
   61 SDYLLNTTKE CETVMTKFLA FEPQSEIDRF AKDASQYNFQ LSSSSKEVVP NNASPASATG 120
  121 ARPVSVSNGA ANTEREKKSP QKDKRKSAFG NIGHRLASAS SSLTHNDLMN NEFSDSTNNS 180
  181 SLKSKKSSHT LRSKVGSIFG RNKTKNKRQQ QSSSNSHIQA SITETPN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [378-604]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSSTRVSSTA TSSIYQKQRR PTYSSSKSNN WTPGEASDTP PLPPHATPKN VDAPVTADTP  60
   61 PAQTFTPSEV PPSTPQQSSP PTAKEPDSSN LPKTVPISIS QPPLQPQSKT KPLPVEPASP 120
  121 SISLPTATVD NQPSGQVDSR PLHIRAPALP PSRKQNFIHN RDSQLYDSLP NHGSGATPTS 180
  181 SSLSSIPQER PVSTLSSQIT GELRELNPQA TGSSTSLVGQ SLFQHSS

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.75
Match: 1deqA
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [605-730]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDTSQFGLNA SIAEVLNASF KDGMLQNSQL IGEIALNYLP NSVMNSPLPI GINLRINNGA  60
   61 KFEKVILNQA FIERVAPEEF KVNPSFIDSR TLGAIKYSIK EPIAPIVIHP VWRFESHQAS 120
  121 VVLTVK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [731-870]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPSLPDEIS QIVIEDLVVF VNIDGANATS ALSKPQGSFS KEKKRITWRF KEPVVLTRNG  60
   61 EGQRLIARFI TDGLAHESAK GVITKFTISE TDNVALPHSG AGSGITLTCQ ELDENNPFGG 120
  121 EWLDVNTKRT LTTGNYHGLA 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle