| Protein: | STE50 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 346 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for STE50.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..346] | [1..346] |
|
|
6.0E-57 | [154..325] | [80..242] |
|
|
3.0E-28 | [232..325] | [157..262] |
|
|
6.0E-26 | [220..327] | [380..490] |
|
|
3.0E-24 | [199..324] | [177..297] |
|
Region A: Residues: [1-196] |
1 11 21 31 41 51
| | | | | |
1 MEDGKQAINE GSNDASPDLD VNGTILMNNE DFSQWSVDDV ITWCISTLEV EETDPLCQRL 60
61 RENDIVGDLL PELCLQDCQD LCDGDLNKAI KFKILINKMR DSKLEWKDDK TQEDMITVLK 120
121 NLYTTTSAKL QEFQSQYTRL RMDVLDVMKT SSSSSPINTH GVSTTVPSSN NTIIPSSDGV 180
181 SLSQTDYFDT VHNRQS
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| binding | 2.68693141392111 | bayes_pls_golite062009 |
| protein binding | 2.12913758162323 | bayes_pls_golite062009 |
| SAM domain binding | 2.00592266938182 | bayes_pls_golite062009 |
| transcription regulator activity | 0.48507851856487 | bayes_pls_golite062009 |
| DNA binding | 0.100984195487788 | bayes_pls_golite062009 |
| nucleic acid binding | 0.0714547564567439 | bayes_pls_golite062009 |
|
Region A: Residues: [197-346] |
1 11 21 31 41 51
| | | | | |
1 PSRRESPVTV FRQPSLSHSK SLHKDSKNKV PQISTNQSHP SAVSTANTPG PSPNEALKQL 60
61 RASKEDSCER ILKNAMKRHN LADQDWRQYV LVICYGDQER LLELNEKPVI IFKNLKQQGL 120
121 HPAIMLRRRG DFEEVAMMNG SDNVTPGGRL
|
| Detection Method: | |
| Confidence: | 27.744727 |
| Match: | PF00788 |
| Description: | Ras association (RalGDS/AF-6) domain |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [213-346] |
1 11 21 31 41 51
| | | | | |
1 SHSKSLHKDS KNKVPQISTN QSHPSAVSTA NTPGPSPNEA LKQLRASKED SCERILKNAM 60
61 KRHNLADQDW RQYVLVICYG DQERLLELNE KPVIIFKNLK QQGLHPAIML RRRGDFEEVA 120
121 MMNGSDNVTP GGRL
|
| Detection Method: | |
| Confidence: | 1.78 |
| Match: | 1wxaA |
| Description: | Solution Structure of Ras-binding Domain in Mouse AF-6 Protein |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.0688320293797 | bayes_pls_golite062009 |
| protein binding | 1.72968950672856 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.172760623576326 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.156922202244152 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.0437862640556833 | bayes_pls_golite062009 |
