YRC Public Data Repository - Protein Structure Prediction

Protein:	YCL001W-B
Organism:	Saccharomyces cerevisiae
Length:	84 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YCL001W-B.

Description	E-value	Query Range	Subject Range
gi\|19387279 - gi\|19387279\|gb\|AAL87190.1\|AF480497_18 putative pelota [Oryza sativa (japonica cultivar-group)]	8.0E-23	[1..79]	[346..424]
PEL2_ARATH - Protein PELOTA 2 OS=Arabidopsis thaliana GN=PEL2 PE=3 SV=1	1.0E-22	[1..79]	[295..373]
erf1 - translation release factor eRF1 DOM34_SCHPO - Protein dom34 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dom34 PE=1 SV=1	1.0E-21	[1..79]	[278..356]
ETF1 - eukaryotic translation termination factor 1 ERF1_MOUSE - Eukaryotic peptide chain release factor subunit 1 OS=Mus musculus GN=Etf1 PE=1 SV=4 ERF1_MESAU - Eukaryotic peptide chain release factor subunit 1 OS=Mesocricetus auratus GN=ETF1 PE=1 SV=3 gi\|118097222 - gi\|118097222\|ref\|XP_414511.2\| PREDICTED: similar to C11 protein [Gallus gallus] ERF1_RABIT - Eukaryotic peptide chain release factor subunit 1 OS=Oryctolagus cuniculus GN=ETF1 PE=1 SV=3 gi\|114601971, gi... - gi\|114601971\|ref\|XP_001171542.1\| PREDICTED: eukaryotic translation termination factor 1 isoform 3 [P... gi\|126290367 - gi\|126290367\|ref\|XP_001368222.1\| PREDICTED: similar to C11 protein [Monodelphis domestica] tr\|M3WU44\|M3WU44... - Uncharacterized protein OS=Felis catus GN=ETF1 PE=4 SV=1 ERF1_RAT - Eukaryotic peptide chain release factor subunit 1 OS=Rattus norvegicus GN=Etf1 PE=2 SV=3 gi\|73970878, gi\|... - gi\|73978635\|ref\|XP_531922.2\| PREDICTED: similar to eukaryotic translation termination factor 1 (pred... ENSCJAT00000013296 - null gi\|109078786 - gi\|109078786\|ref\|XP_001113021.1\| PREDICTED: similar to eukaryotic translation termination factor 1 (... ERF1_BOVIN - Eukaryotic peptide chain release factor subunit 1 OS=Bos taurus GN=ETF1 PE=2 SV=3	6.0E-21	[1..80]	[287..403]
gi\|15489222 - gi\|15489222\|gb\|AAH13717.1\| Eukaryotic translation termination factor 1 [Mus musculus]	7.0E-21	[1..80]	[287..403]
ERF1_XENLA - Eukaryotic peptide chain release factor subunit 1 OS=Xenopus laevis GN=etf1 PE=2 SV=1	2.0E-20	[1..80]	[287..403]
gi\|13094940 - gi\|13094940\|gb\|AAK12090.1\|AF317832_1 eukaryotic release factor 1 [Sterkiella histriomuscorum]	2.0E-20	[1..80]	[292..408]
gi\|220944832, gi... - gi\|220954670\|gb\|ACL89878.1\| eRF1-PA [synthetic construct], gi\|220944832\|gb\|ACL84959.1\| eRF1-PA [synt... gi\|194118161, gi... - gi\|195160369\|ref\|XP_002021048.1\| GL25132 [Drosophila persimilis], gi\|194118161\|gb\|EDW40204.1\| GL2513... eRF1-PC, eRF1-PB... - The gene eukaryotic release factor 1 is referred to in FlyBase by the symbol Dmel\eRF1 (CG5605, FBgn...	2.0E-20	[1..80]	[287..404]

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Predicted Domain #1

Region A:
Residues: [1-84]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDFLEHLSK DDNKAWYGAE ETERAAKLDA IETLLITDSV LKRNDVKKRE KYLDLIENSG  60
   61 NNNGKIFVLS TSKITVSNLT NQQI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.0
Match:	1dt9A_
Description:	Middle domain of eukaryotic peptide chain release factor subunit 1, ERF1; C-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1; N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.0620088599292285	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: