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View Structure Prediction Details

Protein: REI1
Organism: Saccharomyces cerevisiae
Length: 393 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for REI1.

Description E-value Query
Range
Subject
Range
gi|38382750, gi|... - gi|38382750|gb|AAH62309.1| Zinc finger protein 79 [Homo sapiens], gi|24307937|ref|NP_009066.1| zinc ...
gi|208968181 - gi|208968181|dbj|BAG73929.1| zinc finger protein 79 [synthetic construct]
0.0 [5..289] [191..486]
Z287_MOUSE, ZN28... - Zinc finger protein 287 OS=Mus musculus GN=Znf287 PE=2 SV=1, (Q9EQB9) Zinc finger protein 287 (Zfp-2...
0.0 [2..318] [417..739]

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Predicted Domain #1
Region A:
Residues: [1-94]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSGVYTCN SCVLTFDSSD EQRAHMKSDW HRYNLKRRVA QLPPISFETF DSKVSAAAAS  60
   61 TSKSAEKEKP VTKKELKRRE KQALLEKKKK LLEI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.69897
Match: 1meyG_
Description: Designed zinc finger protein
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [95-290]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ARANMLENMQ KSQEGNTPDL SKLSLQENEE NKEKEEPKKE EPEQLTEEEM AERVMQENVR  60
   61 NRVDIPLEQC LFCEHNKHFK DVEENLEHMF RTHGFYIPEQ KYLVDKIGLV KYMSEKIGLG 120
  121 NICIVCNYQG RTLTAVRQHM LAKRHCKIPY ESEDERLEIS EFYDFTSSYA NFNSNTTPDN 180
  181 EDDWEDVGSD EAGSDD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.522879
Match: 1tf6A_
Description: Transcription factor IIIA, TFIIIA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.22788923931596 bayes_pls_golite062009
RNA binding 1.74380511533595 bayes_pls_golite062009
protein binding 1.40325872764913 bayes_pls_golite062009
nucleic acid binding 1.34680997308743 bayes_pls_golite062009
DNA binding 1.1931409893677 bayes_pls_golite062009
transcription regulator activity 0.956307663356759 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.61308065188272 bayes_pls_golite062009
transcription factor activity 0.136882694830461 bayes_pls_golite062009
chromatin binding 0.0298489654874197 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [291-393]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDLPQEYLYN DGIELHLPTG IKVGHRSLQR YYKQDLKPEV ILTEGQGTLV AAETRSFLPA  60
   61 FDKKGVQTQQ RVWQTERFDK KRLDKRSAKF VNNQPHYRDQ LLQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle