YRC Public Data Repository - Protein Structure Prediction

Protein:	TAE1
Organism:	Saccharomyces cerevisiae
Length:	232 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAE1.

Description	E-value	Query Range	Subject Range
gi\|190408588 - gi\|190408588\|gb\|EDV11853.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] NTM1_YEAST - Alpha N-terminal protein methyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c... TAE1 - AdoMet-dependent proline methyltransferase; catalyzes the dimethylation of ribosomal proteins Rpl12 ...	4.0E-47	[1..232]	[1..232]
gi\|6523567 - gi\|6523567\|emb\|CAB62288.1\| hypothetical protein [Zygosaccharomyces rouxii]	3.0E-45	[6..229]	[7..230]
CG1675-PA - This gene is referred to in FlyBase by the symbol Dmel\CG1675 (CG1675, FBgn0033457). It is a protein... gi\|220951056, gi... - gi\|220960510\|gb\|ACL92791.1\| CG1675-PA [synthetic construct], gi\|220951056\|gb\|ACL88071.1\| CG1675-PA [...	8.0E-40	[3..230]	[55..273]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-38	[3..216]	[65..280]
gi\|3560531 - gi\|3560531\|gb\|AAC34988.1\| cycloartenol-C24-methyltransferase [Oryza sativa subsp. japonica]	5.0E-38	[10..225]	[54..267]
UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... UBIE_VIBCM - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... gi\|229508366, gi... - gi\|229508366\|ref\|ZP_04397870.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229346129, gi... - gi\|229517066\|ref\|ZP_04406512.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229520118, gi... - gi\|229520118\|ref\|ZP_04409546.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229527169, gi... - gi\|229527169\|ref\|ZP_04416563.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229369296, gi... - gi\|229606641\|ref\|YP_002877289.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vi... gi\|121587669, gi... - gi\|121587669\|ref\|ZP_01677432.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|124115249, gi... - gi\|153214643\|ref\|ZP_01949519.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|254851469, gi... - gi\|75829374\|ref\|ZP_00758679.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|153222877, gi... - gi\|153222877\|ref\|ZP_01953501.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|153801700, gi... - gi\|153801700\|ref\|ZP_01956286.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|116216422, gi... - gi\|75823221\|ref\|ZP_00752740.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|153818222, gi... - gi\|153818222\|ref\|ZP_01970889.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... UBIE_VIBC3 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... gi\|126520347, gi... - gi\|229508952\|ref\|ZP_04398442.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|121727801, gi... - gi\|75816414\|ref\|ZP_00746885.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|254291829, gi... - gi\|254291829\|ref\|ZP_04962613.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|153829106, gi... - gi\|153829106\|ref\|ZP_01981773.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Vibrio cholerae GN=ubiE PE=3 SV=1 gi\|149739586, gi... - gi\|153826648\|ref\|ZP_01979315.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c...	5.0E-38	[7..200]	[35..208]
gi\|17229295, gi\|... - gi\|17229295\|ref\|NP_485843.1\| gamma-tocopherol methyltransferase [Nostoc sp. PCC 7120], gi\|17130893\|d... gi\|25532225 - pir\|\|AE2031 gamma-tocopherol methyltransferase [imported] - Nostoc sp. (strain PCC 7120)	1.0E-37	[9..214]	[11..223]
gi\|3560474 - gi\|3560474\|gb\|AAC34951.1\| S-adenosyl-methionine-sterol-C- methyltransferase [Nicotiana tabacum]	2.0E-37	[10..225]	[54..267]

Back

Predicted Domain #1

Region A:
Residues: [1-232]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVPADSHIK YEDAIDYWTD VDATVDGVLG GYGEGTVVPT MDVLGSNNFL RKLKSRMLPQ  60
   61 ENNVKYAVDI GAGIGRVSKT MLHKHAAKID LVEPVKPFIE QMHVELAELK DKGQIGQIYE 120
  121 VGMQDWTPDA GKYWLIWCQW CVGHLPDAEL VAFLKRCIVG LQPNGTIVVK ENNTPTDTDD 180
  181 FDETDSSVTR SDAKFRQIFE EAGLKLIASE RQRGLPRELY PVRMYALKPM PN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	24.522879
Match:	1l1eA_
Description:	PccA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methyltransferase activity	3.57681394097837	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	3.49392219433935	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	3.39429041855776	bayes_pls_golite062009
RNA methyltransferase activity	3.07428840534971	bayes_pls_golite062009
transferase activity	2.926540904444	bayes_pls_golite062009
rRNA methyltransferase activity	2.5924681776558	bayes_pls_golite062009
tRNA methyltransferase activity	1.76571145896453	bayes_pls_golite062009
N-methyltransferase activity	1.57269280784007	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
protein methyltransferase activity	0.94499223839747	bayes_pls_golite062009
transcription regulator activity	0.914549843668268	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	0.794703281700029	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	0.716476158062361	bayes_pls_golite062009
DNA binding	0.71058003448013	bayes_pls_golite062009
nucleic acid binding	0.698509190696763	bayes_pls_golite062009
binding	0.383237930789959	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	0.0854264678700428	bayes_pls_golite062009
histone methyltransferase activity	0.0408000230099101	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: