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View Structure Prediction Details

Protein: MRPS5
Organism: Saccharomyces cerevisiae
Length: 307 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MRPS5.

Description E-value Query
Range
Subject
Range
gi|207347484 - gi|207347484|gb|EDZ73638.1| YBR251Wp-like protein [Saccharomyces cerevisiae AWRI1631]
MRPS5 - Mitochondrial ribosomal protein of the small subunit
gi|151946637 - gi|151946637|gb|EDN64859.1| mitochondrial ribosomal protein [Saccharomyces cerevisiae YJM789]
gi|190408599 - gi|190408599|gb|EDV11864.1| ribosomal protein S5 [Saccharomyces cerevisiae RM11-1a]
RT05_YEAST - 37S ribosomal protein S5, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...
3.0E-97 [1..307] [1..307]
gi|2920833 - gi|2920833|gb|AAC04625.1| ribosomal protein S2 [Rattus norvegicus]
5.0E-75 [97..291] [11..215]
RS2_MOUSE - 40S ribosomal protein S2 OS=Mus musculus GN=Rps2 PE=1 SV=3
gi|57718 - gi|57718|emb|CAA40679.1| ribosomal protein S2 [Rattus rattus]
gi|55249864 - gb|AAH86024.1| Unknown (protein for MGC:98099) [Xenopus laevis]
gi|223975107 - gi|223975107|gb|ACN31741.1| unknown [Zea mays]
RS2_RAT - 40S ribosomal protein S2 OS=Rattus norvegicus GN=Rps2 PE=1 SV=1
5.0E-75 [97..291] [54..258]
RS2_BOVIN - (O18789) 40S ribosomal protein S2 (Fragment)
2.0E-74 [97..291] [47..251]
RS2_ICTPU - 40S ribosomal protein S2 OS=Ictalurus punctatus GN=rps2 PE=2 SV=1
4.0E-74 [97..291] [39..243]
RR5_ARATH - 30S ribosomal protein S5, chloroplastic OS=Arabidopsis thaliana GN=rps5 PE=2 SV=1
7.0E-74 [7..302] [25..303]
RS2_CRIGR - 40S ribosomal protein S2 (Fragment) OS=Cricetulus griseus GN=RPS2 PE=2 SV=1
6.0E-73 [105..291] [2..198]

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Predicted Domain #1
Region A:
Residues: [1-136]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKRQLSTSV RYLQHYDESL LSRYYPESLL KSIKLAQQTI PEDTKFRVSR NVEFAPPYLD  60
   61 DFTKIHPFWD YKPGMPHLHA QEENNNFSIF RWDQVQQPLP GEGNILPPGV SLPNDGGRKS 120
  121 KSADVAAGLH KQTGVD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [137-307]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDYITRKLTM KPLVMKRVSN QTGKGKIASF YALVVVGDKN GMVGLGEGKS REEMSKAIFK  60
   61 AHWDAVRNLK EIPRYENRTI YGDIDFRYHG VKLHLRSAKP GFGLRVNHVI FEICECAGIK 120
  121 DLSGKVYKSR NDMNIAKGTI EAFTKAQKTL DEVALGRGKK LVDVRKVYYS S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 204.9794
Match: 1fjgE_
Description: Ribosomal protein S5, C-terminal domain; Ribosomal S5 protein, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural constituent of ribosome 6.7575603459566 bayes_pls_golite062009
structural molecule activity 6.24187874355454 bayes_pls_golite062009
RNA binding 3.5405508156591 bayes_pls_golite062009
nucleic acid binding 3.06806242310926 bayes_pls_golite062009
binding 2.86619976447436 bayes_pls_golite062009
DNA binding 1.59400162385296 bayes_pls_golite062009
3'-5'-exoribonuclease activity 1.56111033008721 bayes_pls_golite062009
protein binding 1.43319050998069 bayes_pls_golite062009
transcription regulator activity 1.36103792167395 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 1.35935222635763 bayes_pls_golite062009
exoribonuclease activity 1.31205157616894 bayes_pls_golite062009
3'-5' exonuclease activity 1.10842504252923 bayes_pls_golite062009
double-stranded RNA binding 0.967560318725736 bayes_pls_golite062009
mRNA binding 0.625703291171316 bayes_pls_golite062009
transcription factor activity 0.442070779997034 bayes_pls_golite062009
cytoskeletal protein binding 0.403469167264307 bayes_pls_golite062009
RNA helicase activity 0.222896865667011 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle