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View Structure Prediction Details

Protein: ALG7
Organism: Saccharomyces cerevisiae
Length: 448 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ALG7.

Description E-value Query
Range
Subject
Range
gi|151946629 - gi|151946629|gb|EDN64851.1| UDP-N-acetylglucosamine-1-P transferase [Saccharomyces cerevisiae YJM789...
GPT_YEAST - UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Saccharomyces c...
ALG7 - UDP-N-acetyl-glucosamine-1-P transferase, transfers Glc-Nac-P from UDP-GlcNac to Dol-P in the ER in ...
gi|190408607 - gi|190408607|gb|EDV11872.1| UDP-N-acetyl-glucosamine-1-P transferase [Saccharomyces cerevisiae RM11-...
gi|207347499 - gi|207347499|gb|EDZ73650.1| YBR243Cp-like protein [Saccharomyces cerevisiae AWRI1631]
2.0E-99 [1..448] [1..448]
gi|145231987 - gi|145231987|ref|XP_001399460.1| hypothetical protein An02g03240 [Aspergillus niger]
gi|18677129, gi|... - gi|18677129|gb|AAL78196.1|AF126048_1 UDP-N-acetylglucosamine:dolichyl phosphate N-acetylglucosamine-...
8.0E-86 [3..444] [16..462]
gpt2 - UDP-N-acetylglucosamine--dolichyl-phosphateN-acetylglucosaminephosphotransferase
GPT_SCHPO - UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Schizosaccharom...
2.0E-84 [5..444] [6..446]
GPT_CRIGR - UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Cricetulus gris...
8.0E-83 [17..440] [3..407]
GPT_CRILO - UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Cricetulus long...
gi|109413 - pir||A37813 UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7...
9.0E-83 [17..440] [3..407]
gi|12002052 - gi|12002052|gb|AAG43168.1| GlcNAc-1-P transferase [Homo sapiens]
3.0E-82 [17..440] [3..407]
GPT_MOUSE - UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Mus musculus GN...
3.0E-82 [20..440] [8..409]
gi|2569954 - gi|2569954|emb|CAA67366.1| UDP-N-acetylglucosamine--dolichyl- phosphateN-acetylglucosaminephosphotra...
7.0E-74 [25..442] [52..482]

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Predicted Domain #1
Region A:
Residues: [1-115]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRLFSLALI TCLIYYSKNQ GPSALVAAVG FGIAGYLATD MLIPRVGKSF IKIGLFGKDL  60
   61 SKPGRPVLPE TIGAIPAAVY LFVMFIYIPF IFYKYMVITT SGGGHRDVSV VEDNG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.467 a.1.1 Globin-like
View Download 0.467 a.1.1 Globin-like
View Download 0.386 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.401 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.401 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.661 d.79.2 Tubulin/Dihydroxyacetone kinase C-terminal domain
View Download 0.661 d.79.2 Tubulin/Dihydroxyacetone kinase C-terminal domain
View Download 0.642 d.79.2 Tubulin/Dihydroxyacetone kinase C-terminal domain
View Download 0.629 d.79.2 Tubulin/Dihydroxyacetone kinase C-terminal domain
View Download 0.629 d.79.2 Tubulin/Dihydroxyacetone kinase C-terminal domain
View Download 0.384 f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.375 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.360 a.4.5 "Winged helix" DNA-binding domain
View Download 0.349 a.1.1 Globin-like
View Download 0.340 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.330 a.142.1 PTS-regulatory domain, PRD
View Download 0.323 f.14.1 Voltage-gated potassium channels
View Download 0.308 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.298 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.293 a.71.2 Helical domain of Sec23/24
View Download 0.289 d.58.8 Viral DNA-binding domain
View Download 0.288 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.287 a.24.3 Cytochromes
View Download 0.287 a.64.1 Saposin
View Download 0.281 d.13.1 HIT-like
View Download 0.280 d.58.9 RuBisCO, large subunit, small (N-terminal) domain
View Download 0.279 a.24.9 alpha-catenin/vinculin
View Download 0.273 a.24.3 Cytochromes
View Download 0.247 a.47.2 t-snare proteins
View Download 0.240 c.49.1 Pyruvate kinase, C-terminal domain
View Download 0.239 a.24.9 alpha-catenin/vinculin
View Download 0.237 a.2.7 tRNA-binding arm
View Download 0.236 d.202.1 Transcription factor NusA, N-terminal domain
View Download 0.234 a.19.1 Fertilization protein
View Download 0.226 a.47.2 t-snare proteins
View Download 0.225 i.11.1 Computational models partly based on NMR data
View Download 0.222 d.56.1 GroEL-intermediate domain like
View Download 0.220 d.58.21 Molybdenum cofactor biosynthesis protein C, MoaC
View Download 0.220 a.7.1 Spectrin repeat
View Download 0.217 d.224.1 SufE-like
View Download 0.211 d.111.1 PR-1-like
View Download 0.210 d.52.2 GMP synthetase C-terminal dimerisation domain
View Download 0.209 a.61.1 Retroviral matrix proteins
View Download 0.206 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.206 d.58.16 Poly(A) polymerase, C-terminal domain
View Download 0.204 d.164.1 SMAD MH1 domain
View Download 0.204 d.52.3 Prokaryotic type KH domain (KH-domain type II)

Predicted Domain #2
Region A:
Residues: [116-339]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSNIFPHDK LSEYLSAILC LESTVLLGIA DDLFDLRWRH KFFLPAIAAI PLLMVYYVDF  60
   61 GVTHVLIPGF MERWLKKTSV DLGLWYYVYM ASMAIFCPNS INILAGVNGL EVGQCIVLAI 120
  121 LALLNDLLYF SMGPLATRDS HRFSAVLIIP FLGVSLALWK WNRWPATVFV GDTYCYFAGM 180
  181 VFAVVGILGH FSKTMLLLFI PQIVNFIYSC PQLFKLVPCP RHRL

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 84.356547
Match: PF00953
Description: Glycosyl transferase family 4

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [340-448]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKFNEKDGLM YPSRANLKEE PPKSIFKPIL KLLYCLHLID LEFDENNEII STSNMTLINL  60
   61 TLVWFGPMRE DKLCNTILKL QFCIGILALL GRHAIGAIIF GHDNLWTVR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.675 0.268 protein amino acid N-linked glycosylation b.55.1 PH domain-like
View Download 0.592 0.183 protein amino acid N-linked glycosylation a.25.1 Ferritin-like
View Download 0.675 0.158 aerobic respiration b.55.1 PH domain-like
View Download 0.592 0.108 aerobic respiration a.25.1 Ferritin-like
View Download 0.679 0.074 aerobic respiration a.35.1 lambda repressor-like DNA-binding domains
View Download 0.565 0.020 protein amino acid N-linked glycosylation a.24.4 Hemerythrin
View Download 0.534 0.009 protein amino acid N-linked glycosylation d.82.2 Frataxin-like
View Download 0.636 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.588 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.565 N/A N/A d.204.1 Ribosome binding protein Y (YfiA homologue)
View Download 0.515 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.495 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.489 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.487 N/A N/A c.15.1 BRCT domain
View Download 0.475 N/A N/A a.46.1 Methionine synthase domain
View Download 0.441 N/A N/A a.24.3 Cytochromes
View Download 0.439 N/A N/A a.29.2 Bromodomain
View Download 0.407 N/A N/A d.198.1 Type III secretory system chaperone
View Download 0.396 N/A N/A a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.385 N/A N/A c.48.1 TK C-terminal domain-like
View Download 0.385 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.385 N/A N/A a.77.1 DEATH domain
View Download 0.385 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.381 N/A N/A a.130.1 Chorismate mutase II
View Download 0.375 N/A N/A d.58.21 Molybdenum cofactor biosynthesis protein C, MoaC
View Download 0.367 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.364 N/A N/A a.7.1 Spectrin repeat
View Download 0.356 N/A N/A a.24.3 Cytochromes
View Download 0.352 N/A N/A d.137.1 Monooxygenase (hydroxylase) regulatory protein
View Download 0.342 N/A N/A a.133.1 Phospholipase A2, PLA2
View Download 0.340 N/A N/A a.74.1 Cyclin-like
View Download 0.338 N/A N/A c.50.1 Macro domain-like
View Download 0.336 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.335 N/A N/A a.40.1 Calponin-homology domain, CH-domain
View Download 0.334 N/A N/A a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.319 N/A N/A c.52.2 tRNA splicing endonuclease, C-terminal domain
View Download 0.318 N/A N/A a.7.8 GAT domain
View Download 0.317 N/A N/A b.59.1 XRCC4, N-terminal domain
View Download 0.316 N/A N/A a.72.1 Functional domain of the splicing factor Prp18
View Download 0.311 N/A N/A d.82.2 Frataxin-like
View Download 0.307 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.305 N/A N/A a.74.1 Cyclin-like
View Download 0.304 N/A N/A d.58.13 Anticodon-binding domain of PheRS
View Download 0.304 N/A N/A a.4.1 Homeodomain-like
View Download 0.303 N/A N/A a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.302 N/A N/A d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.293 N/A N/A a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.291 N/A N/A c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.289 N/A N/A c.44.2 Enzyme IIB-cellobiose
View Download 0.287 N/A N/A a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.284 N/A N/A a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.277 N/A N/A c.48.1 TK C-terminal domain-like
View Download 0.274 N/A N/A c.47.1 Thioredoxin-like
View Download 0.273 N/A N/A c.23.12 Formate/glycerate dehydrogenase catalytic domain-like
View Download 0.265 N/A N/A a.1.1 Globin-like
View Download 0.263 N/A N/A d.26.1 FKBP-like
View Download 0.262 N/A N/A d.131.1 DNA clamp
View Download 0.256 N/A N/A a.24.3 Cytochromes
View Download 0.256 N/A N/A b.61.3 D-aminopeptidase, middle and C-terminal domains
View Download 0.256 N/A N/A a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.254 N/A N/A d.58.17 Metal-binding domain
View Download 0.249 N/A N/A d.58.3 Protease propeptides/inhibitors
View Download 0.243 N/A N/A d.79.1 YjgF-like
View Download 0.238 N/A N/A a.8.2 Plasmid maintenance system epsilon/zeta, antidote epsilon subunit
View Download 0.236 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.235 N/A N/A a.24.2 Aspartate receptor, ligand-binding domain
View Download 0.231 N/A N/A d.54.1 Enolase N-terminal domain-like
View Download 0.231 N/A N/A d.94.1 HPr-like
View Download 0.228 N/A N/A a.64.1 Saposin
View Download 0.220 N/A N/A d.93.1 SH2 domain
View Download 0.215 N/A N/A d.109.1 Actin depolymerizing proteins
View Download 0.214 N/A N/A d.131.1 DNA clamp
View Download 0.214 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.213 N/A N/A d.58.48 MTH1187-like
View Download 0.210 N/A N/A c.95.1 Thiolase-like
View Download 0.209 N/A N/A d.80.1 Tautomerase/MIF
View Download 0.207 N/A N/A a.64.1 Saposin
View Download 0.203 N/A N/A d.9.1 Interleukin 8-like chemokines


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle