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View Structure Prediction Details

Protein: ERT1
Organism: Saccharomyces cerevisiae
Length: 529 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ERT1.

Description E-value Query
Range
Subject
Range
ERT1 - Transcriptional regulator of nonfermentable carbon utilization; GFP-fusion protein localizes to cyto...
ERT1_YEAST - Transcription activator of gluconeogenesis ERT1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2...
0.0 [1..529] [1..529]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
8.0E-53 [3..455] [30..522]
gi|18376338 - gi|18376338|emb|CAD21084.1| conserved hypothetical protein [Neurospora crassa]
gi|164427437, gi... - gi|164427437|ref|XP_955876.2| hypothetical protein NCU03489 [Neurospora crassa OR74A], gi|157071742|...
7.0E-48 [13..229] [8..227]
gi|1706177 - sp|P52959|CT1B_FUSSO CUTINASE TRANSCRIPTION FACTOR 1 BETA
CTF1B_FUSSO - Cutinase transcription factor 1 beta OS=Fusarium solani subsp. pisi GN=CTF1-BETA PE=2 SV=1
3.0E-43 [3..191] [14..231]
SPAC139.03 - transcription factor, zf-fungal binuclear cluster type
YII3_SCHPO - Uncharacterized transcriptional regulatory protein C139.03 OS=Schizosaccharomyces pombe (strain 972 ...
8.0E-38 [21..199] [4..183]
gi|166488 - gi|166488|gb|AAA32686.1| regulatory protein
4.0E-21 [39..168] [18..153]
AMDR_EMENI - Acetamidase regulatory protein OS=Emericella nidulans GN=amdR PE=4 SV=1
5.0E-21 [39..162] [19..150]

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Predicted Domain #1
Region A:
Residues: [1-171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCTPDENDYK TSTDPDTSAN TNHTLEKKKR KKRKNTNVAC VNCSRLHVSC EAKRPCLRCI  60
   61 SKGLTATCVD APRKKSKYLA GIPNRELPMN IQPDLPPRKI MIPIYNNSSN SSLNVNNMGE 120
  121 QQKFTSPQHI VHKAKFLSNA ADSEYSILSN IIYQDTLSNK IPIDILYSNT N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.0
Match: 1hwtC_
Description: Hap1 (Cyp1); HAP1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.46021754022299 bayes_pls_golite062009
nucleic acid binding 3.26455198324141 bayes_pls_golite062009
DNA binding 3.25588366587125 bayes_pls_golite062009
binding 2.32645838605286 bayes_pls_golite062009
transcription factor activity 2.20574348407066 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.54700248976411 bayes_pls_golite062009
sequence-specific DNA binding 1.34348800608209 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.28573362149629 bayes_pls_golite062009
transcription activator activity 0.335097584119319 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [172-353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STSNSTIGNS SNNSPTGTNT SPEETEMEKI RQLYSEQRAN IPPHPYPSSN QNVYSILLGP  60
   61 NSAKIVASQV NLFANHFPLV PVDSADNSLN FKRLLPRDPS EKSSQINWDS SINQYYLNSE 120
  121 TVTFPELAIP LKRRKNHLVS VSLESCSPDA ANIKSNVEWE HSLRYSTPME IYTSINAPFS 180
  181 HT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [354-529]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGFHHLLVYL KHRFNQQDLV KMCRSIAEFR PIFIACSVTL TEEDMIFMEQ CYQRTLLEYV  60
   61 KFIAQIGTPT CIWRRNGQIS YVNEEFEILC GWTREELLNK MTFIVEIMDD ESVRDYFKTL 120
  121 SKVAYRDFRG SEKMKVCRLL SPIKGKIIHC CCMWTLKRDV SGLPLMILGN FMPILN

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 13.346787
Match: PF00989
Description: PAS fold

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle