YRC Public Data Repository - Protein Structure Prediction

Protein:	DER1
Organism:	Saccharomyces cerevisiae
Length:	211 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DER1.

Description	E-value	Query Range	Subject Range
DERL2_MOUSE - Derlin-2 OS=Mus musculus GN=Derl2 PE=1 SV=2 gi\|149053255, gi... - gi\|149053255\|gb\|EDM05072.1\| rCG34415, isoform CRA_c [Rattus norvegicus], gi\|109491204\|ref\|XP_0010799...	2.0E-56	[3..201]	[4..202]
gi\|220949568, gi... - gi\|220958434\|gb\|ACL91760.1\| CG14899-PA [synthetic construct], gi\|220949568\|gb\|ACL87327.1\| CG14899-PA... CG14899-PA - This gene is referred to in FlyBase by the symbol Dmel\CG14899 (CG14899, FBgn0038438). It is a prote...	2.0E-53	[4..202]	[3..201]
DER22_ARATH - Derlin-2.2 OS=Arabidopsis thaliana GN=DER2.2 PE=2 SV=1	4.0E-52	[1..201]	[1..211]
gi\|1352236, gi\|1... - gi\|1352236\|sp\|P38307.2\|DER1_YEAST RecName: Full=Degradation in the endoplasmic reticulum protein 1, ... gi\|190408646 - gi\|190408646\|gb\|EDV11911.1\| degradation in the endoplasmic reticulum protein 1 [Saccharomyces cerevi... gi\|207347564 - gi\|207347564\|gb\|EDZ73691.1\| YBR201Wp-like protein [Saccharomyces cerevisiae AWRI1631]	2.0E-51	[1..211]	[1..211]
gi\|15777933, gi\|... - gi\|15777933\|dbj\|BAB68409.1\| putative NADH oxidoreductase complex I subunit homolog. [Homo sapiens], ...	2.0E-49	[3..201]	[4..202]

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Predicted Domain #1

Region A:
Residues: [1-134]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDAVILNLLG DIPLVTRLWT IGCLVLSGLT SLRIVDPGKV VYSYDLVFKK GQYGRLLYSI  60
   61 FDYGAFNWIS MINIFVSANH LSTLENSFNL RRKFCWIIFL LLVILVKMTS IEQPAASLGV 120
  121 LLHENLVYYE LKKN

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.545407789079971	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [135-211]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNQMNVRFFG AIDVSPSIFP IYMNAVMYFV YKRSWLEIAM NFMPGHVIYY MDDIIGKIYG  60
   61 IDLCKSPYDW FRNTETP