YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: DER1
Organism: Saccharomyces cerevisiae
Length: 211 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DER1.

Description E-value Query
Range
Subject
Range
DERL2_MOUSE - Derlin-2 OS=Mus musculus GN=Derl2 PE=1 SV=2
gi|149053255, gi... - gi|149053255|gb|EDM05072.1| rCG34415, isoform CRA_c [Rattus norvegicus], gi|109491204|ref|XP_0010799...
2.0E-56 [3..201] [4..202]
gi|220949568, gi... - gi|220958434|gb|ACL91760.1| CG14899-PA [synthetic construct], gi|220949568|gb|ACL87327.1| CG14899-PA...
CG14899-PA - This gene is referred to in FlyBase by the symbol Dmel\CG14899 (CG14899, FBgn0038438). It is a prote...
2.0E-53 [4..202] [3..201]
DER22_ARATH - Derlin-2.2 OS=Arabidopsis thaliana GN=DER2.2 PE=2 SV=1
4.0E-52 [1..201] [1..211]
gi|1352236, gi|1... - gi|1352236|sp|P38307.2|DER1_YEAST RecName: Full=Degradation in the endoplasmic reticulum protein 1, ...
gi|190408646 - gi|190408646|gb|EDV11911.1| degradation in the endoplasmic reticulum protein 1 [Saccharomyces cerevi...
gi|207347564 - gi|207347564|gb|EDZ73691.1| YBR201Wp-like protein [Saccharomyces cerevisiae AWRI1631]
2.0E-51 [1..211] [1..211]
gi|15777933, gi|... - gi|15777933|dbj|BAB68409.1| putative NADH oxidoreductase complex I subunit homolog. [Homo sapiens], ...
2.0E-49 [3..201] [4..202]

Back

Predicted Domain #1
Region A:
Residues: [1-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDAVILNLLG DIPLVTRLWT IGCLVLSGLT SLRIVDPGKV VYSYDLVFKK GQYGRLLYSI  60
   61 FDYGAFNWIS MINIFVSANH LSTLENSFNL RRKFCWIIFL LLVILVKMTS IEQPAASLGV 120
  121 LLHENLVYYE LKKN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
catalytic activity 0.545407789079971 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [135-211]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNQMNVRFFG AIDVSPSIFP IYMNAVMYFV YKRSWLEIAM NFMPGHVIYY MDDIIGKIYG  60
   61 IDLCKSPYDW FRNTETP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.792 0.070 ER-associated protein catabolic process a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.578 0.015 ER-associated protein catabolic process a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.694 0.012 ER-associated protein catabolic process a.50.1 Anaphylotoxins (complement system)
View Download 0.519 N/A N/A a.50.1 Anaphylotoxins (complement system)
View Download 0.516 N/A N/A a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.500 N/A N/A d.6.1 Prion-like
View Download 0.486 N/A N/A a.4.1 Homeodomain-like
View Download 0.485 N/A N/A a.4.12 TrpR-like
View Download 0.472 N/A N/A a.144.1 PABC (PABP) domain
View Download 0.460 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.460 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.437 N/A N/A a.4.1 Homeodomain-like
View Download 0.433 N/A N/A a.74.1 Cyclin-like
View Download 0.429 N/A N/A a.74.1 Cyclin-like
View Download 0.428 N/A N/A a.50.1 Anaphylotoxins (complement system)
View Download 0.426 N/A N/A a.4.1 Homeodomain-like
View Download 0.407 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.405 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.398 N/A N/A a.64.1 Saposin
View Download 0.397 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.395 N/A N/A a.64.1 Saposin
View Download 0.376 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.366 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.365 N/A N/A a.23.5 Hemolysin expression modulating protein HHA
View Download 0.353 N/A N/A a.74.1 Cyclin-like
View Download 0.346 N/A N/A a.4.8 Ribosomal protein S18
View Download 0.343 N/A N/A a.4.1 Homeodomain-like
View Download 0.341 N/A N/A a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.331 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.331 N/A N/A a.4.12 TrpR-like
View Download 0.328 N/A N/A a.64.1 Saposin
View Download 0.327 N/A N/A a.64.1 Saposin
View Download 0.323 N/A N/A a.4.1 Homeodomain-like
View Download 0.322 N/A N/A a.77.1 DEATH domain
View Download 0.318 N/A N/A a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.313 N/A N/A d.58.11 EF-G/eEF-2 domains III and V
View Download 0.313 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.308 N/A N/A a.16.1 S15/NS1 RNA-binding domain
View Download 0.307 N/A N/A a.4.1 Homeodomain-like
View Download 0.305 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.304 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.304 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.304 N/A N/A a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.302 N/A N/A a.74.1 Cyclin-like
View Download 0.302 N/A N/A a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.300 N/A N/A a.23.5 Hemolysin expression modulating protein HHA
View Download 0.299 N/A N/A d.68.3 SirA-like
View Download 0.296 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.295 N/A N/A a.4.8 Ribosomal protein S18
View Download 0.293 N/A N/A a.85.1 Hemocyanin, N-terminal domain
View Download 0.292 N/A N/A d.68.3 SirA-like
View Download 0.291 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.284 N/A N/A a.60.2 RuvA domain 2-like
View Download 0.284 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.284 N/A N/A a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.283 N/A N/A a.74.1 Cyclin-like
View Download 0.282 N/A N/A a.144.2 Ribosomal protein L20
View Download 0.279 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.278 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.274 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.273 N/A N/A d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.266 N/A N/A d.54.1 Enolase N-terminal domain-like
View Download 0.263 N/A N/A a.4.1 Homeodomain-like
View Download 0.255 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.255 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.254 N/A N/A c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.247 N/A N/A a.4.8 Ribosomal protein S18
View Download 0.246 N/A N/A a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.243 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.240 N/A N/A a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.239 N/A N/A a.4.1 Homeodomain-like
View Download 0.239 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.239 N/A N/A d.58.17 Metal-binding domain
View Download 0.237 N/A N/A a.51.1 Cytochrome c oxidase subunit h
View Download 0.236 N/A N/A d.74.2 C-terminal domain of arginine repressor
View Download 0.233 N/A N/A d.58.48 MTH1187-like
View Download 0.233 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.232 N/A N/A a.3.1 Cytochrome c
View Download 0.230 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.229 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.228 N/A N/A d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.226 N/A N/A d.58.49 YajQ-like
View Download 0.223 N/A N/A a.4.12 TrpR-like
View Download 0.222 N/A N/A d.58.17 Metal-binding domain
View Download 0.221 N/A N/A a.77.1 DEATH domain
View Download 0.221 N/A N/A a.23.5 Hemolysin expression modulating protein HHA
View Download 0.220 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.218 N/A N/A a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.217 N/A N/A a.4.12 TrpR-like
View Download 0.216 N/A N/A a.4.12 TrpR-like
View Download 0.211 N/A N/A d.146.1 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
View Download 0.210 N/A N/A a.4.1 Homeodomain-like
View Download 0.208 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.208 N/A N/A a.60.2 RuvA domain 2-like
View Download 0.206 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.205 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.205 N/A N/A a.29.4 RecG, N-terminal domain
View Download 0.204 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.204 N/A N/A a.130.1 Chorismate mutase II
View Download 0.203 N/A N/A a.4.1 Homeodomain-like
View Download 0.203 N/A N/A a.60.2 RuvA domain 2-like
View Download 0.203 N/A N/A a.50.1 Anaphylotoxins (complement system)
View Download 0.201 N/A N/A a.4.11 RNA polymerase subunit RPB10
View Download 0.200 N/A N/A a.74.1 Cyclin-like
View Download 0.200 N/A N/A a.2.7 tRNA-binding arm
View Download 0.200 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle