| Protein: | TBS1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1094 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TBS1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..952] | [1..952] |
|
|
7.0E-82 | [47..780] | [1..628] |
|
|
8.0E-81 | [75..862] | [41..736] |
|
|
8.0E-79 | [63..763] | [8..597] |
|
|
2.0E-77 | [71..732] | [3..607] |
|
Region A: Residues: [1-57] |
1 11 21 31 41 51
| | | | | |
1 MNMDSGITSS HGSMDKTQKQ SSEWAANQKH NQRVENTRVL MGPAVPAMPP VPSNFPP
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.731 | 0.853 | nucleus | a.4.1 | Homeodomain-like |
| View | Download | 0.558 | 0.853 | nucleus | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.444 | 0.853 | nucleus | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.731 | 0.853 | nucleus | a.4.1 | Homeodomain-like |
| View | Download | 0.558 | 0.853 | nucleus | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.554 | 0.853 | nucleus | a.4.1 | Homeodomain-like |
| View | Download | 0.444 | 0.853 | nucleus | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.437 | 0.853 | nucleus | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.437 | 0.853 | nucleus | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.404 | 0.853 | nucleus | a.4.1 | Homeodomain-like |
| View | Download | 0.358 | 0.853 | nucleus | a.4.1 | Homeodomain-like |
| View | Download | 0.335 | 0.853 | nucleus | a.159.1 | Protein serine/threonine phosphatase 2C, C-terminal domain |
| View | Download | 0.317 | 0.853 | nucleus | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.305 | 0.853 | nucleus | d.48.1 | RecA protein, C-terminal domain |
| View | Download | 0.282 | 0.853 | nucleus | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.274 | 0.853 | nucleus | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.270 | 0.853 | nucleus | d.7.1 | LysM domain |
| View | Download | 0.246 | 0.853 | nucleus | a.38.1 | Helix-loop-helix DNA-binding domain |
| View | Download | 0.241 | 0.853 | nucleus | g.58.1 | Pheromone ER-23 |
| View | Download | 0.227 | 0.853 | nucleus | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.219 | 0.853 | nucleus | a.126.1 | Serum albumin-like |
| View | Download | 0.214 | 0.853 | nucleus | a.60.5 | Barrier-to-autointegration factor, BAF |
|
Region A: Residues: [58-178] |
1 11 21 31 41 51
| | | | | |
1 VPTGTIMSPQ LSPFPDHRLR HHPLAHMMPA DKNFLAYNME SFKSRVTKAC DYCRKRKIRC 60
61 TEIEPISGKC RNCIKYNKDC TFHFHEELKR RREEALNNKG NGKSVKKPRL DKENKFKDEN 120
121 F
|
| Detection Method: | |
| Confidence: | 44.512579 |
| Match: | 1cld__ |
| Description: | CD2-Lac9 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nucleic acid binding | 2.55832554210202 | bayes_pls_golite062009 |
| DNA binding | 2.48009340951204 | bayes_pls_golite062009 |
| transcription regulator activity | 2.39344671016496 | bayes_pls_golite062009 |
| binding | 2.32645838605286 | bayes_pls_golite062009 |
| transcription factor activity | 1.25308658158845 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.75311920044374 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.68524247899289 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 0.53107237892739 | bayes_pls_golite062009 |
|
Region A: Residues: [179-338] |
1 11 21 31 41 51
| | | | | |
1 DIAVRSRNTS STDSSPKLHT NLSQEYIGVS AGKSASDKED TWPDFVPIDR TVLEKIELNH 60
61 TKVAGKVFVL EEICKNMKGT IEKLAEKSKI DVIDKEYMKR PKRKQYSKAL LTKQKMFHFR 120
121 QNVLSHLTDE EFLSPINEMF TTTFKYSILQ TKLVLDFSFR
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.587 | a.7.4 | Smac/diablo |
| View | Download | 0.600 | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.586 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.793 | a.26.1 | 4-helical cytokines |
| View | Download | 0.695 | f.31.1 | Photosystem I reaction center subunit XI, PsaL |
| View | Download | 0.581 | a.148.1 | Arp2/3 complex 21 kDa subunit ARPC3 |
| View | Download | 0.576 | a.24.3 | Cytochromes |
| View | Download | 0.566 | a.63.1 | Apolipophorin-III |
| View | Download | 0.560 | a.7.1 | Spectrin repeat |
| View | Download | 0.556 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.551 | a.7.4 | Smac/diablo |
| View | Download | 0.549 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.533 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.514 | a.24.5 | TMV-like viral coat proteins |
| View | Download | 0.507 | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.506 | d.19.1 | MHC antigen-recognition domain |
| View | Download | 0.504 | a.1.1 | Globin-like |
| View | Download | 0.494 | a.25.1 | Ferritin-like |
| View | Download | 0.491 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.472 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.462 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.459 | a.124.1 | Phospholipase C/P1 nuclease |
| View | Download | 0.452 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.448 | a.149.1 | RNase III endonuclease catalytic domain |
| View | Download | 0.446 | a.7.4 | Smac/diablo |
| View | Download | 0.446 | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.443 | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.441 | a.7.4 | Smac/diablo |
| View | Download | 0.441 | a.26.1 | 4-helical cytokines |
| View | Download | 0.437 | a.26.1 | 4-helical cytokines |
| View | Download | 0.432 | a.63.1 | Apolipophorin-III |
| View | Download | 0.430 | a.25.1 | Ferritin-like |
| View | Download | 0.430 | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.426 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.422 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.420 | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
| View | Download | 0.420 | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.414 | a.87.1 | DBL homology domain (DH-domain) |
| View | Download | 0.407 | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.398 | a.24.3 | Cytochromes |
| View | Download | 0.385 | a.26.1 | 4-helical cytokines |
| View | Download | 0.384 | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.383 | a.24.2 | Aspartate receptor, ligand-binding domain |
| View | Download | 0.383 | a.24.1 | Apolipoprotein |
| View | Download | 0.374 | a.24.3 | Cytochromes |
| View | Download | 0.370 | a.63.1 | Apolipophorin-III |
| View | Download | 0.368 | a.24.1 | Apolipoprotein |
| View | Download | 0.362 | a.1.1 | Globin-like |
| View | Download | 0.359 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.347 | a.26.1 | 4-helical cytokines |
| View | Download | 0.346 | f.35.1 | Multidrug efflux transporter AcrB transmembrane domain |
| View | Download | 0.345 | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.344 | a.24.3 | Cytochromes |
| View | Download | 0.343 | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.342 | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.342 | a.22.1 | Histone-fold |
| View | Download | 0.338 | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.336 | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.334 | f.35.1 | Multidrug efflux transporter AcrB transmembrane domain |
| View | Download | 0.331 | a.1.1 | Globin-like |
| View | Download | 0.331 | a.24.1 | Apolipoprotein |
| View | Download | 0.325 | f.25.1 | Cytochrome c oxidase subunit III-like |
| View | Download | 0.316 | c.49.1 | Pyruvate kinase, C-terminal domain |
| View | Download | 0.312 | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.309 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.308 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.308 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.304 | a.91.1 | Regulator of G-protein signalling, RGS |
| View | Download | 0.300 | a.185.1 | Gametocyte protein Pfg27 |
| View | Download | 0.300 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.290 | a.1.1 | Globin-like |
| View | Download | 0.288 | a.25.1 | Ferritin-like |
| View | Download | 0.288 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.282 | a.24.1 | Apolipoprotein |
| View | Download | 0.281 | f.1.2 | Diphtheria toxin, middle domain |
| View | Download | 0.280 | d.19.1 | MHC antigen-recognition domain |
| View | Download | 0.274 | a.22.1 | Histone-fold |
| View | Download | 0.270 | c.23.1 | CheY-like |
| View | Download | 0.269 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.267 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.266 | a.24.1 | Apolipoprotein |
| View | Download | 0.266 | a.62.1 | Hepatitis B viral capsid (hbcag) |
| View | Download | 0.262 | a.4.1 | Homeodomain-like |
| View | Download | 0.257 | a.2.3 | Chaperone J-domain |
| View | Download | 0.255 | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.252 | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.252 | a.123.1 | Nuclear receptor ligand-binding domain |
| View | Download | 0.251 | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.249 | a.118.10 | Phosphoinositide-binding clathrin adaptor, N-terminal domain |
| View | Download | 0.249 | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.248 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.247 | a.123.1 | Nuclear receptor ligand-binding domain |
| View | Download | 0.244 | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.242 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.240 | a.24.4 | Hemerythrin |
| View | Download | 0.237 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.236 | d.91.1 | N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 |
| View | Download | 0.235 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.232 | a.26.1 | 4-helical cytokines |
| View | Download | 0.231 | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.229 | f.35.1 | Multidrug efflux transporter AcrB transmembrane domain |
| View | Download | 0.226 | d.109.2 | C-terminal, gelsolin-like domain of Sec23/24 |
| View | Download | 0.225 | a.47.2 | t-snare proteins |
| View | Download | 0.225 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.223 | a.7.8 | GAT domain |
| View | Download | 0.222 | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.221 | d.124.1 | Ribonuclease Rh-like |
| View | Download | 0.221 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.217 | a.19.1 | Fertilization protein |
| View | Download | 0.214 | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.213 | f.1.3 | delta-Endotoxin (insectocide), N-terminal domain |
| View | Download | 0.212 | d.13.1 | HIT-like |
| View | Download | 0.209 | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.208 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.207 | f.35.1 | Multidrug efflux transporter AcrB transmembrane domain |
| View | Download | 0.206 | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.205 | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.203 | a.1.1 | Globin-like |
| View | Download | 0.201 | c.23.16 | Class I glutamine amidotransferase-like |
| Term | Confidence | Notes |
| nucleic acid binding | 2.36440811505803 | bayes_pls_golite062009 |
| DNA binding | 2.25848660128916 | bayes_pls_golite062009 |
| binding | 2.23525969523197 | bayes_pls_golite062009 |
| transcription regulator activity | 2.17762225700059 | bayes_pls_golite062009 |
| transcription factor activity | 1.07713564675134 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.523017357555093 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.479128525355337 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 0.176810808981692 | bayes_pls_golite062009 |
|
Region A: Residues: [339-624] |
1 11 21 31 41 51
| | | | | |
1 SASSPSSDNI LYPLPRLAIA KRLLKNIKCP SLASLLHIVD VDQCLQFADV HFDPAKGRLT 60
61 SSQAFLLNIC LCLGATVTNF EEKQELVDED NHETYYFEKF ELWRLRSFTF LNSVYYYHKL 120
121 SVARADMTAL KALLLLAKFA QQKISASSAV KVLSVAIKVA LDLRLNLHST YEDLELDEII 180
181 KRRRLWCYCF STDKFFSVVL SRPPFLKEEN TDVLTDESYV ELFRDKILPN LSIKYDDSKL 240
241 EGVKDIVSVV NLLANHLEYV PYIQSYFLSR LSLIESQIYY SCFSIR
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [625-915] |
1 11 21 31 41 51
| | | | | |
1 TTLDDTLDEI IENVLENQKA LDRMRDDLPT ILSLENYKEN MRILSLDSSK LDFEVSCCTT 60
61 ILLHLRWYHQ KITLSLFVIS IIGDNLDQRE SSRHDIAEII RRSRLDFKRN CIEVLNILKD 120
121 FEYYPTVQNE FLYFSLTTVF SMFLYLSEIM VNDEHAMETG YIIGLLRDTH TRMLGSEERC 180
181 LSVHNLKWQT SLFFYTFFLR STMEKFNLTS KYAKFYAFDS NYYEGVLNRL VKHTRESKDD 240
241 MVELLKTSFI NKEKMAAFGS FVTEDQEKME VSFNIFNEIT IQDLNFLQFS S
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [916-975] |
1 11 21 31 41 51
| | | | | |
1 IPKLWENKTL EPGEEYHHSN GTNTDNNETT GADDTDDNNN NNNNNNKNGN NSSSTINNNN 60
61
|
| Detection Method: | |
| Confidence: | 7.16 |
| Match: | 1l8mA |
| Description: | No description for 1l8mA was found. |
|
Region A: Residues: [976-1094] |
1 11 21 31 41 51
| | | | | |
1 NNYSNSNNND NDNNINDDDD DDDDDDDDDD DDDDDDDNDD DYSNNGADDD EEDDDYDRSL 60
61 FPTGLASLLD ASYPERTAND YRDENEQSNK LFEKIEGHLE HGVFFYDRDF FFKNVCVKM
|
| Detection Method: | |
| Confidence: | 7.16 |
| Match: | 1l8mA |
| Description: | No description for 1l8mA was found. |
