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View Structure Prediction Details

Protein: YRO2
Organism: Saccharomyces cerevisiae
Length: 344 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YRO2.

Description E-value Query
Range
Subject
Range
MRH1 - Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the aut...
gi|190404995 - gi|190404995|gb|EDV08262.1| protein YRO2 [Saccharomyces cerevisiae RM11-1a]
MRH1_YEAST - Protein MRH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MRH1 PE=1 SV=1
gi|151942019 - gi|151942019|gb|EDN60375.1| Hsp30p-like membrane protein [Saccharomyces cerevisiae YJM789]
4.0E-89 [1..294] [1..295]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-66 [13..305] [8..284]
F123_CORVE - (O74631) Protein FDD123 (CvHSP30/1)
FD123_TRAVE - Protein FDD123 OS=Trametes versicolor GN=FDD123 PE=2 SV=1
5.0E-62 [12..296] [2..277]
gi|13924710 - gi|13924710|gb|AAK49108.1| opsin 1 [Coccidioides posadasii]
1.0E-56 [20..270] [19..267]
gi|9858875 - gi|9858875|gb|AAG01180.1|AF290180_1 opsin [Leptosphaeria maculans]
2.0E-55 [20..264] [39..285]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDYVELLKR GGNEAIKINP PTGADFHITS RGSDWLFTVF CVNLLFGVIL VPLMFRKPVK  60
   61 DRFVYYTAIA PNLFMSIAYF TMASNL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 96.626727
Match: 1gu8A_
Description: Sensory rhodopsin II
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor activity 5.1157224036515 bayes_pls_golite062009
transmembrane receptor activity 4.85722830910254 bayes_pls_golite062009
signal transducer activity 4.75286640345932 bayes_pls_golite062009
molecular transducer activity 4.75286640345932 bayes_pls_golite062009
G-protein coupled receptor activity 4.35314551656946 bayes_pls_golite062009
peptide receptor activity 2.68526520969168 bayes_pls_golite062009
peptide receptor activity, G-protein coupled 2.66975845749013 bayes_pls_golite062009
binding 2.36534865182258 bayes_pls_golite062009
neurotransmitter receptor activity 2.27610825294925 bayes_pls_golite062009
neurotransmitter binding 2.21173097508311 bayes_pls_golite062009
peptide binding 1.89527944834672 bayes_pls_golite062009
photoreceptor activity 1.79236208142167 bayes_pls_golite062009
G-protein coupled photoreceptor activity 1.68412761754563 bayes_pls_golite062009
neuropeptide receptor activity 1.58990466088334 bayes_pls_golite062009
neuropeptide binding 1.58990466088334 bayes_pls_golite062009
transcription regulator activity 1.31009205588407 bayes_pls_golite062009
G-protein coupled amine receptor activity 1.2298526499749 bayes_pls_golite062009
protein binding 0.516440306486999 bayes_pls_golite062009
opioid receptor activity 0.470988413972081 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [87-344]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GWIPVRAKYN HVQTSTQKEH PGYRQIFYAR YVGWFLAFPW PIIQMSLLGG TPLWQIAFNV  60
   61 GMTEIFTVCW LIAACVHSTY KWGYYTIGIG AAIVVCISLM TTTFNLVKAR GKDVSNVFIT 120
  121 FMSVIMFLWL IAYPTCFGIT DGGNVLQPDS ATIFYGIIDL LILSILPVLF MPLANYLGIE 180
  181 RLGLIFDEEP AEHVGPVAEK KMPSPASFKS SDSDSSIKEK LKLKKKHKKD KKKAKKAKKA 240
  241 KKAKKAQEEE EDVATDSE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 96.626727
Match: 1gu8A_
Description: Sensory rhodopsin II
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle