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View Structure Prediction Details

Protein: COQ1
Organism: Saccharomyces cerevisiae
Length: 473 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COQ1.

Description E-value Query
Range
Subject
Range
COQ1 - Hexaprenyl pyrophosphate synthetase, catalyzes the first step in ubiquinone (coenzyme Q) biosynthesi...
COQ1_YEAST - Hexaprenyl pyrophosphate synthase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S...
0.0 [1..473] [1..473]
gi|6277254 - gi|6277254|dbj|BAA86284.1| geranylgeranyl pyrophosphate synthase [Croton sublyratus]
3.0E-83 [37..432] [20..365]
GGPPS_CATRO - Geranylgeranyl pyrophosphate synthase, chloroplastic OS=Catharanthus roseus GN=GGPS1 PE=3 SV=1
2.0E-81 [42..432] [2..354]
GGPP1_ARATH - Heterodimeric geranylgeranyl pyrophosphate synthase large subunit 1, chloroplastic OS=Arabidopsis th...
1.0E-80 [32..432] [20..368]
gi|17352451 - gi|17352451|gb|AAL17614.2|AF425235_1 geranylgeranyl diphosphate synthase [Abies grandis]
3.0E-78 [22..431] [18..379]
GGPPS_HEVBR - Geranylgeranyl pyrophosphate synthase, chloroplastic OS=Hevea brasiliensis GN=GGPS PE=1 SV=1
1.0E-77 [37..432] [20..367]
GGPPS_SINAL - Geranylgeranyl pyrophosphate synthase, chloroplastic/chromoplastic OS=Sinapis alba GN=GGPS1 PE=1 SV=...
1.0E-76 [32..431] [18..362]

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Predicted Domain #1
Region A:
Residues: [1-101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFQRSGAAHH IKLISSRRCR FKSSFAVALN AASKLVTPKI LWNNPISLVS KEMNTLAKNI  60
   61 VALIGSGHPV LNKVTSYYFE TEGKKVRPLL VLLLSRALSE I

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [102-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PMTERNHLKI DKSDVPEDPI YSKPSQNQLF QRPASSISPL HILHGIKPLN PLTKGPEPLP  60
   61 EETFDKQRGI LPKQRRLAEI VEMIHTASLL HDDVIDHSDT RRGRPSGNAA FTNKMAVLAG 120
  121 DFLLGRATVS ISRLHNPEVV ELMSNSIANL VEGEFMQLKN TSIDADIDTI ENGHKLLPVP 180
  181 SKKLEVKEHD FRVP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [321-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YLKTAALISK SCRCAAILSG ASPAVI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.39794
Match: 1ubx__
Description: Farnesyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [296-320]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRQQGLQLSH DQIIETAFEY YIHKT

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [347-473]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DECYDFGRNL GICFQLVDDM LDFTVSGKDL GKPSGADLKL GIATAPVLFA WKEDPSLGPL  60
   61 ISRNFSERGD VEKTIDSVRL HNGIAKTKIL AEEYRDKALQ NLRDSLPESD ARSALEFLTN 120
  121 SILTRRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.39794
Match: 1ubx__
Description: Farnesyl diphosphate synthase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle