YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: COQ1
Organism: Saccharomyces cerevisiae
Length: 473 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COQ1.

Description E-value Query
Range
Subject
Range
COQ1 - Hexaprenyl pyrophosphate synthetase, catalyzes the first step in ubiquinone (coenzyme Q) biosynthesi...
COQ1_YEAST - Hexaprenyl pyrophosphate synthase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S...
0.0 [1..473] [1..473]
gi|6277254 - gi|6277254|dbj|BAA86284.1| geranylgeranyl pyrophosphate synthase [Croton sublyratus]
3.0E-83 [37..432] [20..365]
GGPPS_CATRO - Geranylgeranyl pyrophosphate synthase, chloroplastic OS=Catharanthus roseus GN=GGPS1 PE=3 SV=1
2.0E-81 [42..432] [2..354]
GGPP1_ARATH - Heterodimeric geranylgeranyl pyrophosphate synthase large subunit 1, chloroplastic OS=Arabidopsis th...
1.0E-80 [32..432] [20..368]
gi|17352451 - gi|17352451|gb|AAL17614.2|AF425235_1 geranylgeranyl diphosphate synthase [Abies grandis]
3.0E-78 [22..431] [18..379]
GGPPS_HEVBR - Geranylgeranyl pyrophosphate synthase, chloroplastic OS=Hevea brasiliensis GN=GGPS PE=1 SV=1
1.0E-77 [37..432] [20..367]
GGPPS_SINAL - Geranylgeranyl pyrophosphate synthase, chloroplastic/chromoplastic OS=Sinapis alba GN=GGPS1 PE=1 SV=...
1.0E-76 [32..431] [18..362]

Back

Predicted Domain #1
Region A:
Residues: [1-101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFQRSGAAHH IKLISSRRCR FKSSFAVALN AASKLVTPKI LWNNPISLVS KEMNTLAKNI  60
   61 VALIGSGHPV LNKVTSYYFE TEGKKVRPLL VLLLSRALSE I

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.580 d.26.1 FKBP-like
View Download 0.618 a.40.1 Calponin-homology domain, CH-domain
View Download 0.556 a.74.1 Cyclin-like
View Download 0.762 a.158.1 F-box domain
View Download 0.577 a.24.17 Group V grass pollen allergen
View Download 0.550 a.70.1 N-terminal domain of the delta subunit of the F1F0-ATP synthase
View Download 0.545 a.7.6 Ribosomal protein S20
View Download 0.543 a.118.1 ARM repeat
View Download 0.540 a.24.3 Cytochromes
View Download 0.512 a.4.5 "Winged helix" DNA-binding domain
View Download 0.509 d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.509 a.4.1 Homeodomain-like
View Download 0.493 a.39.1 EF-hand
View Download 0.486 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.482 a.74.1 Cyclin-like
View Download 0.482 d.56.1 GroEL-intermediate domain like
View Download 0.476 a.21.1 HMG-box
View Download 0.465 a.47.2 t-snare proteins
View Download 0.452 a.39.1 EF-hand
View Download 0.447 a.7.5 Tubulin chaperone cofactor A
View Download 0.434 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.417 a.2.3 Chaperone J-domain
View Download 0.415 a.71.2 Helical domain of Sec23/24
View Download 0.412 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.410 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.406 a.24.17 Group V grass pollen allergen
View Download 0.400 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.386 d.26.1 FKBP-like
View Download 0.385 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.384 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.383 a.118.8 TPR-like
View Download 0.382 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.380 a.134.1 Fungal elicitin
View Download 0.379 a.130.1 Chorismate mutase II
View Download 0.372 a.4.5 "Winged helix" DNA-binding domain
View Download 0.371 a.142.1 PTS-regulatory domain, PRD
View Download 0.367 a.29.2 Bromodomain
View Download 0.366 c.55.4 Translational machinery components
View Download 0.366 a.61.1 Retroviral matrix proteins
View Download 0.363 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.344 a.4.5 "Winged helix" DNA-binding domain
View Download 0.343 d.80.1 Tautomerase/MIF
View Download 0.337 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.324 a.68.1 Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
View Download 0.321 a.4.5 "Winged helix" DNA-binding domain
View Download 0.319 a.4.1 Homeodomain-like
View Download 0.312 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.312 d.195.1 YopH tyrosine phosphatase N-terminal domain
View Download 0.311 a.74.1 Cyclin-like
View Download 0.308 a.29.2 Bromodomain
View Download 0.307 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.302 a.40.1 Calponin-homology domain, CH-domain
View Download 0.296 a.4.5 "Winged helix" DNA-binding domain
View Download 0.296 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.296 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.295 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.283 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.281 a.28.1 ACP-like
View Download 0.281 a.39.4 Hypothetical protein MTH865
View Download 0.281 a.26.1 4-helical cytokines
View Download 0.272 a.4.5 "Winged helix" DNA-binding domain
View Download 0.269 c.78.2 Aspartate/glutamate racemase
View Download 0.266 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.259 a.7.1 Spectrin repeat
View Download 0.250 a.85.1 Hemocyanin, N-terminal domain
View Download 0.248 a.1.1 Globin-like
View Download 0.247 a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.243 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.242 a.77.1 DEATH domain
View Download 0.240 d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.236 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.235 a.91.1 Regulator of G-protein signalling, RGS
View Download 0.235 a.60.1 SAM/Pointed domain
View Download 0.235 a.2.3 Chaperone J-domain
View Download 0.234 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.232 a.90.1 Transcription factor STAT-4 N-domain
View Download 0.229 a.39.1 EF-hand
View Download 0.227 d.26.1 FKBP-like
View Download 0.227 a.39.1 EF-hand
View Download 0.227 a.4.5 "Winged helix" DNA-binding domain
View Download 0.224 a.7.1 Spectrin repeat
View Download 0.223 a.16.1 S15/NS1 RNA-binding domain
View Download 0.219 a.24.4 Hemerythrin
View Download 0.212 a.60.11 Hypothetical protein YjbJ
View Download 0.211 d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.209 a.28.2 Colicin E immunity proteins
View Download 0.209 a.4.1 Homeodomain-like
View Download 0.204 a.4.5 "Winged helix" DNA-binding domain
View Download 0.204 a.4.1 Homeodomain-like

Predicted Domain #2
Region A:
Residues: [102-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PMTERNHLKI DKSDVPEDPI YSKPSQNQLF QRPASSISPL HILHGIKPLN PLTKGPEPLP  60
   61 EETFDKQRGI LPKQRRLAEI VEMIHTASLL HDDVIDHSDT RRGRPSGNAA FTNKMAVLAG 120
  121 DFLLGRATVS ISRLHNPEVV ELMSNSIANL VEGEFMQLKN TSIDADIDTI ENGHKLLPVP 180
  181 SKKLEVKEHD FRVP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [321-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YLKTAALISK SCRCAAILSG ASPAVI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.39794
Match: 1ubx__
Description: Farnesyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [296-320]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRQQGLQLSH DQIIETAFEY YIHKT

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [347-473]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DECYDFGRNL GICFQLVDDM LDFTVSGKDL GKPSGADLKL GIATAPVLFA WKEDPSLGPL  60
   61 ISRNFSERGD VEKTIDSVRL HNGIAKTKIL AEEYRDKALQ NLRDSLPESD ARSALEFLTN 120
  121 SILTRRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.39794
Match: 1ubx__
Description: Farnesyl diphosphate synthase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle