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View Structure Prediction Details

Protein: UBP13
Organism: Saccharomyces cerevisiae
Length: 688 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBP13.

Description E-value Query
Range
Subject
Range
UBP9 - Ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease that cleaves ubiquitin-protein fu...
UBP9_YEAST - Ubiquitin carboxyl-terminal hydrolase 9 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...
2.0E-98 [1..674] [1..673]
gi|6492126, gi|5... - gi|6492126|gb|AAF14190.1|AF106659_1 deubiquitinating enzyme Ubp69 [Rattus norvegicus], gi|51592088|r...
9.0E-84 [99..670] [56..614]
gi|3800764 - gi|3800764|gb|AAC68865.1| ubiquitin specific protease 66 [Gallus gallus]
2.0E-82 [318..670] [38..380]
gi|34874937, gi|... - gi|74218334|dbj|BAE23782.1| unnamed protein product [Mus musculus], gi|34874937|gb|AAQ83304.1| deubi...
3.0E-82 [99..670] [56..615]
gi|16552833, gi|... - gi|21361712|ref|NP_004196.3| ubiquitin specific peptidase 2 isoform a [Homo sapiens], gi|16552833|db...
9.0E-82 [100..670] [57..601]

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Predicted Domain #1
Region A:
Residues: [1-132]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRRWLTISK SGKKKKAVND TITEEVEKVD FKPVNHDIND ELCYSESSDN PSSSLFVSNL  60
   61 DTKETFLNED NNLQISSGLD YSSETCNQGS NYSQDGIFYI SNAKAINAYG GIITQGPEAP 120
  121 ILAMKVSDSM PY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.341 0.308 ubiquitin-specific protease activity a.1.1 Globin-like
View Download 0.306 0.102 ubiquitin-specific protease activity c.23.1 CheY-like
View Download 0.404 0.015 ubiquitin-specific protease activity a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.341 0.013 ubiquitin-specific protease activity c.121.1 Ribose/Galactose isomerase RpiB/AlsB
View Download 0.283 0.011 ubiquitin-specific protease activity c.78.2 Aspartate/glutamate racemase
View Download 0.267 N/A N/A a.118.9 ENTH/VHS domain

Predicted Domain #2
Region A:
Residues: [133-188]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDGSNKVFGY ENFGNTCYCN SVLQCLYNLS SLRENILQFP KKSRESDHPR KKEMRG

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 12.69897
Match: PF00442
Description: No description for PF00442 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [189-531]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKPRIFTEAS FEKSIAGTNG HLPNPKPQSV DDGKPTPVNS VNSNTAGPSE KKSKFFKSFS  60
   61 AKHVQDNNKK EGSPAILTTG KPSSRPQDAP PLIVETPNEP GAPSRLSFEN VTDRPPDVPR 120
  121 KIIVGRVLNY ENPSRGSSNS NNLDLKGESN SSLSTPLDKK DTRRSSSSSQ ISPEHRKKSA 180
  181 LIRGPVLNID HSLNGSDKAT LYSSLRDIFE CITENTYLTG VVSPSSFVDV LKRENVLFNT 240
  241 TMHQDAHEFF NFLLNELSEY IERENKKIAA SDINSDSEPS KSKNFISDLF QGTLTNQIKC 300
  301 LTCDNITSRD EPFLDFPIEV QGDEETDIQE ILKSYHQREM LNG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [532-597]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNKFYCDECC GLQEAERLVG LKQLPDTLTL HLKRFKYSEK QNCNIKLFNN IHYPLTLNVC  60
   61 SSINSK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.704 b.38.1 Sm-like ribonucleoproteins
View Download 0.672 d.17.1 Cystatin/monellin
View Download 0.656 d.95.1 Glucose permease domain IIB
View Download 0.679 b.38.1 Sm-like ribonucleoproteins
View Download 0.653 d.17.1 Cystatin/monellin
View Download 0.575 b.38.1 Sm-like ribonucleoproteins
View Download 0.556 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.530 b.38.1 Sm-like ribonucleoproteins
View Download 0.529 b.38.1 Sm-like ribonucleoproteins
View Download 0.518 b.38.1 Sm-like ribonucleoproteins
View Download 0.514 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.508 b.38.1 Sm-like ribonucleoproteins
View Download 0.501 b.38.1 Sm-like ribonucleoproteins
View Download 0.487 b.38.1 Sm-like ribonucleoproteins
View Download 0.473 b.38.1 Sm-like ribonucleoproteins
View Download 0.450 b.38.1 Sm-like ribonucleoproteins
View Download 0.428 d.17.1 Cystatin/monellin
View Download 0.417 b.38.1 Sm-like ribonucleoproteins
View Download 0.415 b.38.1 Sm-like ribonucleoproteins
View Download 0.375 b.71.1 Glycosyl hydrolase domain
View Download 0.361 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.357 b.71.1 Glycosyl hydrolase domain
View Download 0.330 b.34.1 C-terminal domain of transcriptional repressors
View Download 0.329 d.17.1 Cystatin/monellin
View Download 0.327 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.320 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.301 b.1.2 Fibronectin type III
View Download 0.292 d.17.1 Cystatin/monellin
View Download 0.285 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.281 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.274 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.273 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.256 b.40.2 Bacterial enterotoxins
View Download 0.251 d.17.1 Cystatin/monellin
View Download 0.243 b.36.1 PDZ domain-like
View Download 0.242 b.40.4 Nucleic acid-binding proteins
View Download 0.241 d.17.1 Cystatin/monellin
View Download 0.232 d.17.1 Cystatin/monellin
View Download 0.231 b.1.1 Immunoglobulin
View Download 0.231 d.17.1 Cystatin/monellin
View Download 0.229 b.1.7 Actinoxanthin-like
View Download 0.218 d.17.1 Cystatin/monellin
View Download 0.216 b.40.4 Nucleic acid-binding proteins
View Download 0.211 b.55.1 PH domain-like
View Download 0.206 d.17.1 Cystatin/monellin
View Download 0.206 d.17.1 Cystatin/monellin
View Download 0.204 b.89.1 Cyanovirin-N
View Download 0.204 d.105.1 Clathrin adaptor appendage, alpha and beta chain-specific domain
View Download 0.200 d.129.1 TATA-box binding protein-like

Predicted Domain #5
Region A:
Residues: [598-688]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VCQKYELAGI VVHMGGGPQH GHYVSLCKHE KFGWLLFDDE TVEAVKEETV LEFTGESPNM  60
   61 ATAYVCFIKR CIQTLLKRMI VKIWQKNKMI I

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 23.657577
Match: PF00443
Description: Ubiquitin carboxyl-terminal hydrolase

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
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