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View Structure Prediction Details

Protein: YBL036C
Organism: Saccharomyces cerevisiae
Length: 257 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YBL036C.

Description E-value Query
Range
Subject
Range
YBD6_YEAST - UPF0001 protein YBL036C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YBL036C PE=1 SV=...
YBL036C - Putative non-specific single-domain racemase based on structural similarity; binds pyridoxal 5'-phos...
6.0E-90 [1..257] [1..257]
gi|17978899, gi|... - gi|240256085|ref|NP_567760.4| pyridoxal phosphate binding [Arabidopsis thaliana], gi|21536981|gb|AAM...
6.0E-87 [9..254] [4..243]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-84 [9..254] [4..261]
gi|190689559, gi... - gi|190690923|gb|ACE87236.1| proline synthetase co-transcribed homolog (bacterial) protein [synthetic...
PROSC - proline synthetase co-transcribed homolog (bacterial)
2.0E-82 [11..253] [9..255]
PROSC_MOUSE - Proline synthase co-transcribed bacterial homolog protein OS=Mus musculus GN=Prosc PE=1 SV=1
2.0E-82 [10..253] [8..255]
gi|124526149, gi... - gi|124526149|ref|ZP_01698154.1| alanine racemase domain protein [Escherichia coli B], gi|124502253|g...
EG12979 - UPF0001 family protein, PLP-binding / UPF0001 family protein, PLP-binding; mutant has perturbed isol...
YGGS_ECOL6 - UPF0001 protein YggS OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=yggS PE=3 SV=...
gi|12517497, gi|... - gi|15803490|ref|NP_289523.1| hypothetical protein Z4296 [Escherichia coli O157:H7 EDL933], gi|125174...
gi|89109728, gi|... - gi|89109728|ref|AP_003508.1| hypothetical protein [Escherichia coli str. K-12 substr. W3110], gi|856...
gi|82778278, gi|... - gi|82778278|ref|YP_404626.1| hypothetical protein SDY_3122 [Shigella dysenteriae Sd197], gi|81242426...
gi|81246838, gi|... - gi|82545427|ref|YP_409373.1| hypothetical protein SBO_3040 [Shigella boydii Sb227], gi|81246838|gb|A...
gi|157068092, gi... - gi|75196900|ref|ZP_00706970.1| COG0325: Predicted enzyme with a TIM-barrel fold [Escherichia coli HS...
gi|194426432, gi... - gi|75212427|ref|ZP_00712451.1| COG0325: Predicted enzyme with a TIM-barrel fold [Escherichia coli B1...
gi|187731481, gi... - gi|75178851|ref|ZP_00698887.1| COG0325: Predicted enzyme with a TIM-barrel fold [Shigella boydii BS5...
gi|157155954, gi... - gi|75187675|ref|ZP_00700942.1| COG0325: Predicted enzyme with a TIM-barrel fold [Escherichia coli E2...
gi|75258559, gi|... - gi|75258559|ref|ZP_00729981.1| COG0325: Predicted enzyme with a TIM-barrel fold [Escherichia coli E2...
gi|74313507, gi|... - gi|74313507|ref|YP_311927.1| hypothetical protein SSON_3104 [Shigella sonnei Ss046], gi|73856984|gb|...
gi|75228907, gi|... - gi|75228907|ref|ZP_00715504.1| COG0325: Predicted enzyme with a TIM-barrel fold [Escherichia coli B7...
gi|192959420, gi... - gi|75239479|ref|ZP_00723450.1| COG0325: Predicted enzyme with a TIM-barrel fold [Escherichia coli E1...
gi|195937089 - gi|195937089|ref|ZP_03082471.1| hypothetical protein EscherichcoliO157_11651 [Escherichia coli O157:...
gi|208726015, gi... - gi|208806214|ref|ZP_03248551.1| pyridoxal phosphate enzyme, YggS family [Escherichia coli O157:H7 st...
gi|208733113, gi... - gi|208811836|ref|ZP_03253165.1| pyridoxal phosphate enzyme, YggS family [Escherichia coli O157:H7 st...
gi|208820717, gi... - gi|208820717|ref|ZP_03261037.1| pyridoxal phosphate enzyme, YggS family [Escherichia coli O157:H7 st...
gi|209157268, gi... - gi|209395868|ref|YP_002272431.1| pyridoxal phosphate enzyme, YggS family [Escherichia coli O157:H7 s...
gi|209920410, gi... - gi|209920410|ref|YP_002294494.1| hypothetical protein ECSE_3219 [Escherichia coli SE11], gi|20991366...
gi|215266321, gi... - gi|215488249|ref|YP_002330680.1| predicted enzyme [Escherichia coli O127:H6 str. E2348/69], gi|21526...
gi|217319447, gi... - gi|217327080|ref|ZP_03443163.1| pyridoxal phosphate enzyme, YggS family [Escherichia coli O157:H7 st...
gi|168773410, gi... - gi|187770778|gb|EDU34622.1| alanine racemase family [Escherichia coli O157:H7 str. EC4196], gi|16877...
gi|168781810, gi... - gi|189000521|gb|EDU69507.1| alanine racemase family [Escherichia coli O157:H7 str. EC4076], gi|16878...
gi|168785809, gi... - gi|189374066|gb|EDU92482.1| alanine racemase family [Escherichia coli O157:H7 str. EC869], gi|168785...
gi|189379642, gi... - gi|189379642|gb|EDU98058.1| alanine racemase family [Escherichia coli O157:H7 str. EC508], gi|168797...
gi|170018808, gi... - gi|170018808|ref|YP_001723762.1| alanine racemase domain-containing protein [Escherichia coli ATCC 8...
gi|170082503, gi... - gi|170082503|ref|YP_001731823.1| hypothetical protein ECDH10B_3126 [Escherichia coli str. K-12 subst...
gi|170521101, gi... - gi|170683383|ref|YP_001745112.1| alanine racemase [Escherichia coli SMS-3-5], gi|170521101|gb|ACB192...
gi|194431672, gi... - gi|194431672|ref|ZP_03063963.1| pyridoxal phosphate enzyme, YggS family [Shigella dysenteriae 1012],...
gi|238902073, gi... - gi|238902073|ref|YP_002927869.1| putative enzyme [Escherichia coli BW2952], gi|238862357|gb|ACR64355...
gi|218362278, gi... - gi|218555510|ref|YP_002388423.1| putative enzyme [Escherichia coli IAI1], gi|218362278|emb|CAQ99899....
gi|242378477, gi... - gi|251786204|ref|YP_003000508.1| hypothetical protein B21_02744 [Escherichia coli BL21], gi|24237847...
gi|218696549, gi... - gi|218696549|ref|YP_002404216.1| putative enzyme [Escherichia coli 55989], gi|218353281|emb|CAU99241...
gi|254289621, gi... - gi|254289621|ref|YP_003055369.1| predicted enzyme [Escherichia coli BL21(DE3)], gi|253978928|gb|ACT4...
gi|218371647, gi... - gi|218701661|ref|YP_002409290.1| putative enzyme [Escherichia coli IAI39], gi|218371647|emb|CAR19486...
gi|254038000, gi... - gi|254038000|ref|ZP_04872058.1| pyridoxal phosphate enzyme [Escherichia sp. 1_1_43], gi|226839624|gb...
gi|195183144 - gi|195183144|dbj|BAG66689.1| predicted protein [Escherichia coli O111:H-]
gi|253974762, gi... - gi|254162861|ref|YP_003045969.1| predicted enzyme [Escherichia coli B str. REL606], gi|253974762|gb|...
YGGS_ECOL6 - UPF0001 protein yggS OS=Escherichia coli O6 GN=yggS PE=3 SV=1
gi|254594303, gi... - gi|254794903|ref|YP_003079740.1| predicted enzyme [Escherichia coli O157:H7 str. TW14359], gi|254594...
YGGS_ECO57 - UPF0001 protein YggS OS=Escherichia coli O157:H7 GN=yggS PE=3 SV=1
YGGS_ECOLI - UPF0001 protein yggS - Escherichia coli
EG12979 - UPF0001 family protein, PLP-binding / UPF0001 family protein, PLP-binding; mutant has perturbed isol...
gi|110806859, gi... - gi|110806859|ref|YP_690379.1| hypothetical protein SFV_3005 [Shigella flexneri 5 str. 8401], gi|1106...
gi|168747557, gi... - gi|188017916|gb|EDU56038.1| alanine racemase family [Escherichia coli O157:H7 str. EC4113], gi|16874...
gi|189358401, gi... - gi|189358401|gb|EDU76820.1| alanine racemase family [Escherichia coli O157:H7 str. EC4401], gi|16875...
gi|189369217, gi... - gi|189369217|gb|EDU87633.1| alanine racemase family [Escherichia coli O157:H7 str. EC4501], gi|16876...
gi|13363299, gi|... - gi|15833081|ref|NP_311854.1| hypothetical protein ECs3826 [Escherichia coli O157:H7 str. Sakai], gi|...
gi|168766958, gi... - gi|189363749|gb|EDU82168.1| alanine racemase family [Escherichia coli O157:H7 str. EC4486], gi|16876...
2.0E-79 [14..253] [3..234]

Back

Predicted Domain #1
Region A:
Residues: [1-257]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTGITYDED RKTQLIAQYE SVREVVNAEA KNVHVNENAS KILLLVVSKL KPASDIQILY  60
   61 DHGVREFGEN YVQELIEKAK LLPDDIKWHF IGGLQTNKCK DLAKVPNLYS VETIDSLKKA 120
  121 KKLNESRAKF QPDCNPILCN VQINTSHEDQ KSGLNNEAEI FEVIDFFLSE ECKYIKLNGL 180
  181 MTIGSWNVSH EDSKENRDFA TLVEWKKKID AKFGTSLKLS MGMSADFREA IRQGTAEVRI 240
  241 GTDIFGARPP KNEARII

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1540.69897
Match: 1b54__
Description: "Hypothetical" protein ybl036c
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
alanine racemase activity 2.62362449847897 bayes_pls_golite062009
amino-acid racemase activity 2.31165775898309 bayes_pls_golite062009
racemase and epimerase activity, acting on amino acids and derivatives 2.17003836264776 bayes_pls_golite062009
catalytic activity 1.23611818854966 bayes_pls_golite062009
diaminopimelate decarboxylase activity 0.492894938678183 bayes_pls_golite062009
binding 0.349413451832348 bayes_pls_golite062009
racemase and epimerase activity 0.328743179708914 bayes_pls_golite062009
lyase activity 0.320782640542698 bayes_pls_golite062009
protein binding 0.20402482036521 bayes_pls_golite062009
carboxy-lyase activity 0.14065879331273 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle