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View Structure Prediction Details

Protein: ATS1
Organism: Saccharomyces cerevisiae
Length: 333 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATS1.

Description E-value Query
Range
Subject
Range
gi|15229409 - gi|15229409|ref|NP_188968.1| regulator of chromosome condensation (RCC1) family protein [Arabidopsis...
4.0E-84 [1..331] [210..588]
gi|15088545 - gi|15088545|gb|AAK84081.1|AF326781_2 putative chromosome condensation factor [Triticum monococcum]
6.0E-80 [1..331] [34..414]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-79 [5..314] [6..346]
HERC3 - hect domain and RLD 3
gi|7657152 - ref|NP_055421.1| hect domain and RLD 3 [Homo sapiens]
gi|187252515, gi... - gi|187252515|gb|AAI66672.1| Hect domain and RLD 3 [synthetic construct], gi|168274306|dbj|BAG09573.1...
2.0E-79 [5..314] [2..342]

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Predicted Domain #1
Region A:
Residues: [1-333]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSCVYAFGSN GQRQLGLGHD EDMDTPQRSV PGDDGAIVRK IACGGNHSVM LTNDGNLVGC  60
   61 GDNRRGELDS AQALRQVHDW RPVEVPAPVV DVACGWDTTV IVDADGRVWQ RGGGCYEFTQ 120
  121 QHVPLNSNDE RIAVYGCFQN FVVVQGTRVY GWGSNTKCQL QEPKSRSLKE PVLVYDTGSV 180
  181 AVDYVAMGKD FMVIVDEGGR IVHASGRLPT GFELKQQQKR HNLVVLCMWT SIHLWNARLN 240
  241 TVESFGRGTH SQLFPQERLD FPIVGVATGS EHGILTTANQ EGKSHCYNVY CWGWGEHGNC 300
  301 GPQKASQPGL QLVGQYSGKP RVFGGCATTW IVL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 96.0
Match: 1a12A_
Description: Regulator of chromosome condensation RCC1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.79978015066238 bayes_pls_golite062009
Ran guanyl-nucleotide exchange factor activity 1.12611051197363 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 1.05993294531818 bayes_pls_golite062009
GTPase regulator activity 1.03758696380346 bayes_pls_golite062009
ligase activity 0.957134518791255 bayes_pls_golite062009
guanyl-nucleotide exchange factor activity 0.947267197207143 bayes_pls_golite062009
small GTPase regulator activity 0.882132361980766 bayes_pls_golite062009
protein binding 0.775788303004353 bayes_pls_golite062009
Ras guanyl-nucleotide exchange factor activity 0.642436223706285 bayes_pls_golite062009
catalytic activity 0.261970921089142 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle