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View Structure Prediction Details

Protein: SWC3
Organism: Saccharomyces cerevisiae
Length: 638 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SWC3.

Description E-value Query
Range
Subject
Range
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
2.0E-68 [88..633] [837..1404]
MYH2_BOVIN - Myosin-2 OS=Bos taurus GN=MYH2 PE=2 SV=1
4.0E-67 [88..633] [840..1407]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-67 [88..633] [51..618]
gi|179508, gi|10... - sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta), gi|4557773|ref|NP...
6.0E-67 [88..633] [835..1402]
gi|14250231, gi|... - ref|NP_659210.1| myosin, heavy polypeptide 2, skeletal muscle, adult [Mus musculus], gi|14250231|gb...
2.0E-66 [88..633] [842..1409]

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Predicted Domain #1
Region A:
Residues: [1-52]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFGSNARRR QVRMPAVLRT RSKESSIEQK PASRTRTRSR RGKRGRDDDD DD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [53-444]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDEESDDAYD EVGNDYDEYA SRAKLATNRP FEIVAGLPAS VELPNYNSSL THPQSIKNSG  60
   61 VLYDSLVSSR RTWVQGEMFE LYWRRPKKIV SESTPAATES PTSGTIPLIR DKMQKMCDCV 120
  121 MSGGPHTFKV RLFILKNDKI EQKWQDEQEL KKKEKELKRK NDAEAKRLRM EERKRQQMQK 180
  181 KIAKEQKLQL QKENKAKQKL EQEALKLKRK EEMKKLKEQN KNKQGSPSSS MHDPRMIMNL 240
  241 NLMAQEDPKL NTLMETVAKG LANNSQLEEF KKFIEIAKKR SLEENPVNKR PSVTTTRPAP 300
  301 PSKAKDVAED HRLNSITLVK SSKTAATEPE PKKADDENAE KQQSKEAKTT AESTQVDVKK 360
  361 EEEDVKEKGV KSEDTQKKED NQVVPKRKRR KN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.69897
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [445-638]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIKEDKDMQL TAFQQKYVQG AEIILEYLEF THSRYYLPKK SVVEFLEDTD EIIISWIVIH  60
   61 NSKEIEKFKT KKIKAKLKAD QKLNKEDAKP GSDVEKEVSF NPLFEADCPT PLYTPMTMKL 120
  121 SGIHKRFNQI IRNSVSPMEE VVKEMEKILQ IGTRLSGYNL WYQLDGYDDE ALSESLRFEL 180
  181 NEWEHAMRSR RHKR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle