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View Structure Prediction Details

Protein: SNX12_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 1010 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SNX12_SCHPO.

Description E-value Query
Range
Subject
Range
gi|11359651 - gi|11359651|pir||T49735 related to MDM1 protein [imported] - Neurospora crassa
597.0 [0..18] [983..21]
gi|83766381 - gi|83766381|dbj|BAE56524.1| unnamed protein product [Aspergillus oryzae]
gi|169768110 - gi|169768110|ref|XP_001818526.1| hypothetical protein [Aspergillus oryzae RIB40]
561.0 [0..7] [1001..8]
MDM1 - Intermediate filament protein, required for nuclear and mitochondrial transmission to daughter buds;...
MDM1_YEAST - Structural protein MDM1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MDM1 PE=1 SV=3
481.0 [0..9] [998..4]
gi|46440090, gi|... - gi|68475220|ref|XP_718328.1| possible intermediate filament protein Mdm1p [Candida albicans SC5314],...
orf19.10097 - orf19.2565 CGDID:CAL0002505 Assembly 19, Contig19-20151 (70043, 73141) CDS, translated using codon t...
479.0 [0..5] [1004..6]
gi|27451613 - gi|27451613|gb|AAO15004.1| sorting nexin 13 [Takifugu rubripes]
456.0 [0..6] [1002..63]
CG1514-PA, FBpp0... - This gene is referred to in FlyBase by the symbol Dmel\CG1514 (CG1514, FBgn0029976). It is a protein...
435.0 [0..6] [1007..63]
gi|47222254 - gi|47222254|emb|CAG11133.1| unnamed protein product [Tetraodon nigroviridis]
429.0 [0..6] [1004..15]
gi|109503354 - gi|109503354|ref|XP_224863.4| PREDICTED: similar to sorting nexin 25 [Rattus norvegicus]
420.0 [0..58] [1004..114]

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Predicted Domain #1
Region A:
Residues: [1-83]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYQQHIFYFI TGGIFILWIL AHSFFVKIIY LWASGCLLWY CLETRTFENK NNLGTSEPFL  60
   61 VNPAIFQKRA RQLALSKLLL RQP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [84-305]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LYPGIPEISE EIESIISHFM QKYIKVWSYQ IIPEPTISNS IESHLRKCLM VLLSRVDEID  60
   61 LADVLVKTVL PLITKHLRLF VEAEQLVVGN KAVSFTDHSE LSREVAAKYD HGRLHEAVLL 120
  121 SGNPMVAQKR YLRNWTTQVL SIILPNYYET SPLVLSLVTE VIINTTLLPL VSYISDPDFF 180
  181 NYLIIQASGS IIQRRRKIRR LKRAIRKQSN HFQVGARRLR LK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 7.552842
Match: PF02194.6
Description: No description for PF02194.6 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [306-550]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSQHSFEQYI HEIKKISNIS DARRLRSELM VQRRQLEQTE AFDFEFKQYR ERLQIAIITA  60
   61 EKRISLLSGT PFQHKEAVLF EQVQSLLQIL SDSAAVSCFL EFMERKNRSR YLHFWLVVEG 120
  121 LKESQDDPLN AHMIAPFSDI VSDHTDFTAI VKSYFESVDN PLDIPKPLTN TINKFVNQSK 180
  181 DNLNPDLWVE ARNAMLMAQE HVFDIMQNSD YSEFVNSEIY YRFLAQDVVS DHKSTNSSAT 240
  241 FSRLE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.39794
Match: 1agrE
Description: Regulator of G-protein signalling 4, RGS4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.56462084128628 bayes_pls_golite062009
protein binding 1.55542857306536 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 1.13899380938509 bayes_pls_golite062009
GTPase regulator activity 1.11716566045476 bayes_pls_golite062009
enzyme regulator activity 0.930307440055454 bayes_pls_golite062009
GTPase activator activity 0.845105141539921 bayes_pls_golite062009
enzyme activator activity 0.830104847091967 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [551-691]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELGENIPAIS KQPSYLSISS SSKSINSSPS PSIQLSVSSS ISRDKNLSPL DLELDDPTYS  60
   61 DEEEVLFAPP GDLQLSESID ELNNNIEELK AQLNAINTLI KKAELVADQK QLKSLTKNHQ 120
  121 EIEKAIHRKE RQRDQYMSQE E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [692-1010]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSKLFNRSRV SIDSFKISKE ENTPDFAVYT IRIERLENGH VRSGWMVARR YREFAELHKQ  60
   61 LKQTYPGVRS LKFPQKSIIT SLNKNVLEYR RGALEEYLQS LFRMPEVCDS KMLRMFLSQQ 120
  121 NITAPQMFNP KEVGKKWKQL LEVLGFEVNN SFNASNVNTN SSFSGPISEF LVELFSPNDD 180
  181 AKQQWLPKKT YISILEQLFG GALEKRIRLQ LFQLFTPEKI YRKLREFRRG LEGKSNHDHS 240
  241 KDRRHSRARK PAYADRNQLK AEAGILLASM FPGYTPDIAV KRIFRILQNQ SLNAHVIYTL 300
  301 LDEILLALKK HARSTNKAT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.30103
Match: 2dybA
Description: No description for 2dybA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle