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View Structure Prediction Details

Protein: SYP1_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 818 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SYP1_SCHPO.

Description E-value Query
Range
Subject
Range
gi|109077552 - gi|109077552|ref|XP_001099245.1| PREDICTED: similar to FCH domain only 2 [Macaca mulatta]
457.0 [0..25] [783..20]
gi|58743367 - gi|58743367|ref|NP_620137.1| FCH domain only 2 [Homo sapiens]
gi|117645406 - gi|117645406|emb|CAL38169.1| hypothetical protein [synthetic construct]
456.0 [0..25] [783..20]
gi|109464277 - gi|109464277|ref|XP_219503.4| PREDICTED: similar to FCH domain only 2 [Rattus norvegicus]
455.0 [0..25] [783..66]
gi|114599723 - gi|114599723|ref|XP_526898.2| PREDICTED: FCH domain only 2 isoform 3 [Pan troglodytes]
454.0 [0..25] [783..20]
FCHO2_MOUSE - F-BAR domain only protein 2 OS=Mus musculus GN=Fcho2 PE=1 SV=1
454.0 [0..25] [783..20]
FCHO2_PONPY - FCH domain only protein 2 - Pongo pygmaeus (Orangutan)
FCHO2_PONAB - F-BAR domain only protein 2 OS=Pongo abelii GN=FCHO2 PE=2 SV=1
454.0 [0..25] [783..20]
gi|73950242 - gi|73950242|ref|XP_535271.2| PREDICTED: similar to FCH domain only 2 [Canis familiaris]
447.0 [0..25] [783..127]
gi|76646175 - gi|76646175|ref|XP_869976.1| PREDICTED: similar to FCH domain only 2 isoform 2 [Bos taurus]
434.0 [0..25] [783..20]

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Predicted Domain #1
Region A:
Residues: [1-243]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESLTKTEYV DAFLSNYSPN DSMSIFRQRL EQVRLDNDML SQWIRERMDI ERQYSDQLHK  60
   61 LAMNMQEKNN SSFAFNYAWK QLEGETLEIS RYHSQIIGQI ASQVYKPLID YYTSSPQTAT 120
  121 LRRLAERLST VAEEMASSSV PGLKGLKKKG RDADTKSQND LTASRATWDS DAPLAFEKLQ 180
  181 IVDEERLLIL KQVYLTIASL ETDTALKQQE FFSKSMAVYS DLPIEGEIRQ FMNSTSKVMS 240
  241 SAS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.69897
Match: 2v0oA
Description: No description for 2v0oA was found.

Predicted Domain #2
Region A:
Residues: [244-508]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANKPSKSSGF HINNGKSKEE KSHGENESGG KLKNKMSTLF RRKTIMPKKD KKPSHKSNGR  60
   61 PNKLTAFFNK NSKASSISSA EEHPSNIDDS SIERRHYDSN HSSQIRDHPS TNNNASSYQN 120
  121 FNETSDEGED NDATIRANNV RSSFLEAPLP VQPNVQAETV TPKISSKASP FNKPNSVHSE 180
  181 ASRNTPSSID RENASHSNPI MMHGNDFGGN FNNMQSRSTT TSPTSAVASP APTENEDSNA 240
  241 AIERVANTLR KNPTISRRTR RAGTM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [509-818]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRYATASSDY MESNLGSLPN LSTLSLQSGP DSTATWHPEF PNSSGLSASI VEKYSGELSE  60
   61 DGLLHPSCSG HIFMKYTSDF NTPPPEMGVR VASEFPMSFT HLNDHAVKYG PSENTLSLIP 120
  121 ELLLSPIKVT DFNLHLDSIN GASCIPLTVV QKWKHDESSS SMIAFVKPNP VWRNLGSSLH 180
  181 IEKLVIIVYL GENVLVKSCQ SSPAGEFSRK TSKLKLHLSN INISSSGFKI LAKFAISPSA 240
  241 AIRKPVIEFR IRMVDSSNNP GLTKLFLKPD MFDTTSSSGG SQLESAYEET KVPTSYGIHV 300
  301 RECSVFADMS 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.74
Match: 1gw5M
Description: Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; Mu2 adaptin (clathrin coat assembly protein AP50)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.47443303633602 bayes_pls_golite062009
protein binding 1.05973889460624 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle