YRC Public Data Repository - Protein Structure Prediction

Protein:	ESF2_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	334 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ESF2_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|50759870 - gi\|50759870\|ref\|XP_417821.1\| PREDICTED: similar to PABPC4 protein [Gallus gallus]	221.0	[0..11]	[328..507]
gi\|48734702 - gi\|48734702\|gb\|AAH71591.1\| PABPC4 protein [Homo sapiens]	217.0	[0..11]	[329..100]
gi\|55959639, gi\|... - gi\|66267552\|gb\|AAH94755.1\| PABPC4 protein [Homo sapiens], gi\|55962217\|emb\|CAI12298.1\| poly(A) bindin... gi\|114555673 - gi\|114555673\|ref\|XP_001170937.1\| PREDICTED: poly A binding protein, cytoplasmic 4 isoform 1 [Pan tro...	216.0	[0..11]	[329..100]
gi\|73976775 - gi\|73976775\|ref\|XP_539581.2\| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...	216.0	[0..11]	[329..100]
gi\|76633763 - gi\|76633763\|ref\|XP_882246.1\| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...	216.0	[0..15]	[329..100]

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Predicted Domain #1

Region A:
Residues: [1-108]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTAEQLFGA EEEEKYVDQD LSEDEEDERF LKAIRSSRST KPVVDVLKVK SESSADELEE  60
   61 RDAHLDRFRR DSTFESETSD HEDFSGGSEN ELDEETTKNA NSIKKISL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	19.522879
Match:	1fnxH
Description:	Hu antigen C (Huc)
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [109-334]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEVEKQRKAI KRSGVIYLSR IPPYMAPNKL RQILSQYGKI GRVYLTPESS AKRAQRLRNG  60
   61 GNKRVMYEEG WIEFESKRVA KSVAELLNTN QIGGKKSSWY HDDIWNMKYL PKFKWHHLTE 120
  121 QIAAENAARE SRLKVEIEQG RKQLKQYMRN VENAKMIEGI RKKRSERDTL NVSTEFPEET 180
  181 KDLSEDTKPS KQARRFFGQK SIVSNRNMPT DNAKQQKVEN VLRRVF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.69897
Match:	1l3kA
Description:	Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA binding	4.46119712758726	bayes_pls_golite062009
nucleic acid binding	3.81920018903278	bayes_pls_golite062009
mRNA binding	3.05425904007847	bayes_pls_golite062009
binding	3.05116833253954	bayes_pls_golite062009
	2.36751082234253	bayes_pls_golite062009
transcription regulator activity	1.07788694919471	bayes_pls_golite062009
DNA binding	0.978604858165557	bayes_pls_golite062009
protein binding	0.89093640300829	bayes_pls_golite062009
single-stranded RNA binding	0.852368751354665	bayes_pls_golite062009
snoRNA binding	0.80067755623586	bayes_pls_golite062009
poly-pyrimidine tract binding	0.56829350502235	bayes_pls_golite062009
transcription factor activity	0.234742017105535	bayes_pls_golite062009
structural molecule activity	0.0823205596024605	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: